 gamma-Glutamyltransferase
"gamma-Glutamyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme, sometimes called GGT, with a key role in the synthesis and degradation of GLUTATHIONE; (GSH, a tripeptide that protects cells from many toxins). It catalyzes the transfer of the gamma-glutamyl moiety to an acceptor amino acid.
| Descriptor ID |
D005723
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| MeSH Number(s) |
D08.811.913.050.200.500
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| Concept/Terms |
gamma-Glutamyltransferase- gamma-Glutamyltransferase
- gamma Glutamyltransferase
- Glutamyl Transpeptidase
- Transpeptidase, Glutamyl
- GGTP
- gamma-Glutamyl Transpeptidase
- Transpeptidase, gamma-Glutamyl
- gamma Glutamyl Transpeptidase
- gammaglutamyltransferase
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Below are MeSH descriptors whose meaning is more general than "gamma-Glutamyltransferase".
Below are MeSH descriptors whose meaning is more specific than "gamma-Glutamyltransferase".
This graph shows the total number of publications written about "gamma-Glutamyltransferase" by people in this website by year, and whether "gamma-Glutamyltransferase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 0 | 1 | | 1985 | 0 | 1 | 1 | | 1986 | 0 | 2 | 2 | | 1987 | 1 | 0 | 1 | | 1991 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1999 | 1 | 2 | 3 | | 2003 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "gamma-Glutamyltransferase" by people in Profiles.
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Saag KG, Becker MA, Whelton A, Hunt B, Castillo M, Kisfalvi K, Gunawardhana L. Efficacy and Safety of Febuxostat Extended and Immediate Release in Patients With Gout and Renal Impairment: A Phase III Placebo-Controlled Study. Arthritis Rheumatol. 2019 01; 71(1):143-153.
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Garassino MC, Cho BC, Kim JH, Mazières J, Vansteenkiste J, Lena H, Corral Jaime J, Gray JE, Powderly J, Chouaid C, Bidoli P, Wheatley-Price P, Park K, Soo RA, Huang Y, Wadsworth C, Dennis PA, Rizvi NA. Durvalumab as third-line or later treatment for advanced non-small-cell lung cancer (ATLANTIC): an open-label, single-arm, phase 2 study. Lancet Oncol. 2018 04; 19(4):521-536.
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Abe H, Ochi H, Maekawa T, Hayes CN, Tsuge M, Miki D, Mitsui F, Hiraga N, Imamura M, Takahashi S, Ohishi W, Arihiro K, Kubo M, Nakamura Y, Chayama K. Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients. J Hepatol. 2010 Sep; 53(3):439-43.
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Wu R, Richter S, Zhang RG, Anderson VJ, Missiakas D, Joachimiak A. Crystal structure of Bacillus anthracis transpeptidase enzyme CapD. J Biol Chem. 2009 Sep 04; 284(36):24406-14.
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Saito S, Iida A, Sekine A, Kawauchi S, Higuchi S, Ogawa C, Nakamura Y. Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population. J Hum Genet. 2003; 48(5):249-270.
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Rudin CM, Yang Z, Schumaker LM, VanderWeele DJ, Newkirk K, Egorin MJ, Zuhowski EG, Cullen KJ. Inhibition of glutathione synthesis reverses Bcl-2-mediated cisplatin resistance. Cancer Res. 2003 Jan 15; 63(2):312-8.
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Lipton AJ, Johnson MA, Macdonald T, Lieberman MW, Gozal D, Gaston B. S-nitrosothiols signal the ventilatory response to hypoxia. Nature. 2001 Sep 13; 413(6852):171-4.
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Wallin C, Weber SG, Sandberg M. Glutathione efflux induced by NMDA and kainate: implications in neurotoxicity? J Neurochem. 1999 Oct; 73(4):1566-72.
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Sisley AC, Desai TR, Hynes KL, Gewertz BL, Dudeja PK. Decrease in mucosal alkaline phosphatase: a potential marker of intestinal reperfusion injury. J Lab Clin Med. 1999 Apr; 133(4):335-41.
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Li X, Wallin C, Weber SG, Sandberg M. Net efflux of cysteine, glutathione and related metabolites from rat hippocampal slices during oxygen/glucose deprivation: dependence on gamma-glutamyl transpeptidase. Brain Res. 1999 Jan 02; 815(1):81-8.
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