gamma-Glutamyltransferase
"gamma-Glutamyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme, sometimes called GGT, with a key role in the synthesis and degradation of GLUTATHIONE; (GSH, a tripeptide that protects cells from many toxins). It catalyzes the transfer of the gamma-glutamyl moiety to an acceptor amino acid.
| Descriptor ID |
D005723
|
| MeSH Number(s) |
D08.811.913.050.200.500
|
| Concept/Terms |
gamma-Glutamyltransferase- gamma-Glutamyltransferase
- gamma Glutamyltransferase
- GGTP
- gammaglutamyltransferase
- Glutamyl Transpeptidase
- Transpeptidase, Glutamyl
- gamma-Glutamyl Transpeptidase
- Transpeptidase, gamma-Glutamyl
- gamma Glutamyl Transpeptidase
|
Below are MeSH descriptors whose meaning is more general than "gamma-Glutamyltransferase".
Below are MeSH descriptors whose meaning is more specific than "gamma-Glutamyltransferase".
This graph shows the total number of publications written about "gamma-Glutamyltransferase" by people in this website by year, and whether "gamma-Glutamyltransferase" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1999 | 1 | 2 | 3 |
| 2003 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "gamma-Glutamyltransferase" by people in Profiles.
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Efficacy and Safety of Febuxostat Extended and Immediate Release in Patients With Gout and Renal Impairment: A Phase III Placebo-Controlled Study. Arthritis Rheumatol. 2019 01; 71(1):143-153.
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Durvalumab as third-line or later treatment for advanced non-small-cell lung cancer (ATLANTIC): an open-label, single-arm, phase 2 study. Lancet Oncol. 2018 04; 19(4):521-536.
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Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients. J Hepatol. 2010 Sep; 53(3):439-43.
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Crystal structure of Bacillus anthracis transpeptidase enzyme CapD. J Biol Chem. 2009 Sep 04; 284(36):24406-14.
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Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population. J Hum Genet. 2003; 48(5):249-270.
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Inhibition of glutathione synthesis reverses Bcl-2-mediated cisplatin resistance. Cancer Res. 2003 Jan 15; 63(2):312-8.
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S-nitrosothiols signal the ventilatory response to hypoxia. Nature. 2001 Sep 13; 413(6852):171-4.
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Glutathione efflux induced by NMDA and kainate: implications in neurotoxicity? J Neurochem. 1999 Oct; 73(4):1566-72.
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Decrease in mucosal alkaline phosphatase: a potential marker of intestinal reperfusion injury. J Lab Clin Med. 1999 Apr; 133(4):335-41.
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Net efflux of cysteine, glutathione and related metabolites from rat hippocampal slices during oxygen/glucose deprivation: dependence on gamma-glutamyl transpeptidase. Brain Res. 1999 Jan 02; 815(1):81-8.