"Concanavalin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A MANNOSE/GLUCOSE binding lectin isolated from the jack bean (Canavalia ensiformis). It is a potent mitogen used to stimulate cell proliferation in lymphocytes, primarily T-lymphocyte, cultures.
| Descriptor ID |
D003208
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| MeSH Number(s) |
D12.776.503.499.500 D12.776.765.678.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Concanavalin A".
Below are MeSH descriptors whose meaning is more specific than "Concanavalin A".
This graph shows the total number of publications written about "Concanavalin A" by people in this website by year, and whether "Concanavalin A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 2 | 0 | 2 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Concanavalin A" by people in Profiles.
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Kupffer cells contribute to concanavalin A-induced hepatic injury through a Th1 but not Th17 type response-dependent pathway in mice. Hepatobiliary Pancreat Dis Int. 2011 Apr; 10(2):171-8.
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Essential role of neutrophil mobilization in concanavalin A-induced hepatitis is based on classic IL-6 signaling but not on IL-6 trans-signaling. Biochim Biophys Acta. 2011 Mar; 1812(3):290-301.
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Microtubule-mediated transport of the tumor-suppressor protein Merlin and its mutants. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7311-6.
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Cutting edge: B and T lymphocyte attenuator signaling on NKT cells inhibits cytokine release and tissue injury in early immune responses. J Immunol. 2009 Jul 01; 183(1):32-6.
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Phosphorylation of FADD at serine 194 by CKIalpha regulates its nonapoptotic activities. Mol Cell. 2005 Aug 05; 19(3):321-32.
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The role of herpesvirus entry mediator as a negative regulator of T cell-mediated responses. J Clin Invest. 2005 Mar; 115(3):711-7.
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Histamine: its novel role as an endogenous regulator of Con A-dependent T cell proliferation. Inflamm Res. 2004 Jul; 53(7):324-8.
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Regulation of Con A-dependent cytokine production from CD4+ and CD8+ T lymphocytes by autosecretion of histamine. Inflamm Res. 2004 Mar; 53(3):87-92.
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Identification, purification and partial characterization of tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in bovine pulmonary artery smooth muscle. Mol Cell Biochem. 2003 Dec; 254(1-2):145-55.
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Dynamics in the Mn2+ binding site in single crystals of concanavalin A revealed by high-field EPR spectroscopy. Biochemistry. 2003 Jul 01; 42(25):7863-70.