"Multiple Sclerosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Descriptor ID |
D009103
|
| MeSH Number(s) |
C10.114.375.500 C10.314.350.500 C20.111.258.250.500
|
| Concept/Terms |
Multiple Sclerosis- Multiple Sclerosis
- Sclerosis, Multiple
- Sclerosis, Disseminated
- Disseminated Sclerosis
- MS (Multiple Sclerosis)
|
Below are MeSH descriptors whose meaning is more general than "Multiple Sclerosis".
Below are MeSH descriptors whose meaning is more specific than "Multiple Sclerosis".
This graph shows the total number of publications written about "Multiple Sclerosis" by people in this website by year, and whether "Multiple Sclerosis" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 8 | 0 | 8 |
| 1997 | 2 | 0 | 2 |
| 1998 | 7 | 1 | 8 |
| 1999 | 3 | 0 | 3 |
| 2000 | 1 | 0 | 1 |
| 2002 | 4 | 0 | 4 |
| 2003 | 2 | 0 | 2 |
| 2004 | 3 | 0 | 3 |
| 2005 | 3 | 0 | 3 |
| 2006 | 2 | 0 | 2 |
| 2007 | 5 | 0 | 5 |
| 2008 | 2 | 1 | 3 |
| 2009 | 4 | 0 | 4 |
| 2010 | 4 | 2 | 6 |
| 2011 | 6 | 1 | 7 |
| 2012 | 8 | 1 | 9 |
| 2013 | 7 | 1 | 8 |
| 2014 | 4 | 0 | 4 |
| 2015 | 2 | 1 | 3 |
| 2016 | 2 | 0 | 2 |
| 2017 | 5 | 1 | 6 |
| 2018 | 6 | 0 | 6 |
| 2019 | 4 | 0 | 4 |
| 2020 | 4 | 1 | 5 |
| 2021 | 7 | 0 | 7 |
| 2022 | 7 | 0 | 7 |
| 2023 | 7 | 0 | 7 |
| 2024 | 6 | 2 | 8 |
| 2025 | 5 | 1 | 6 |
| 2026 | 3 | 1 | 4 |
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Below are the most recent publications written about "Multiple Sclerosis" by people in Profiles.
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Ventricular-vascular coupling at rest and immediately following maximal exercise in adults with and without multiple sclerosis. Physiol Rep. 2026 Aug; 14(15):e71044.
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Long-Term IFN-ß Therapy Enhances and Prolongs IFN Responses in Multiple Sclerosis. J Interferon Cytokine Res. 2026 Sep; 46(9):253-263.
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Depression severity and discordance between fatigue patient-reported outcomes in people with multiple sclerosis. Mult Scler Relat Disord. 2026 Jun; 110:107192.
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Myelin sheaths in the central nervous system can withstand damage and dynamically remodel. Science. 2026 Feb 12; 391(6786):eadr4661.
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Impaired inactive limb blood flow regulation in adults with multiple sclerosis during sympathoexcitatory stimuli. Physiol Rep. 2025 12; 13(23):e70694.
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IFN-ß therapy rescues dysregulated IFN-stimulated proteins, serum cytokines, and neurotrophic factors in multiple sclerosis: Multiplex analysis of short-term and long-term IFN responses. PLoS One. 2025; 20(9):e0330867.
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Central and peripheral fatigue indices following resistance exercise with and without blood flow restriction among people with multiple sclerosis. J Neurophysiol. 2025 Sep 01; 134(3):843-855.
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Activity-attenuated serum albumin-fused interleukin-33 suppresses experimental autoimmune encephalomyelitis. Cell Rep Med. 2025 Jul 15; 6(7):102231.
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SMAD2 S-palmitoylation promotes its linker region phosphorylation and TH17 cell differentiation in a mouse model of multiple sclerosis. Sci Signal. 2025 05 27; 18(888):eadr2008.
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Validation of retroactively derived T1 relaxation values from 3D T1-weighted images with clinical and MRI measures of disability in multiple sclerosis. PLoS One. 2025; 20(5):e0323898.