Immunosuppressive Agents
"Immunosuppressive Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
Descriptor ID |
D007166
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MeSH Number(s) |
D27.505.696.477.656
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Immunosuppressive Agents".
Below are MeSH descriptors whose meaning is more specific than "Immunosuppressive Agents".
This graph shows the total number of publications written about "Immunosuppressive Agents" by people in this website by year, and whether "Immunosuppressive Agents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1981 | 1 | 0 | 1 | 1982 | 1 | 1 | 2 | 1984 | 0 | 1 | 1 | 1987 | 1 | 1 | 2 | 1988 | 0 | 3 | 3 | 1989 | 0 | 1 | 1 | 1990 | 15 | 1 | 16 | 1991 | 10 | 2 | 12 | 1992 | 2 | 3 | 5 | 1993 | 8 | 3 | 11 | 1994 | 11 | 3 | 14 | 1995 | 10 | 2 | 12 | 1996 | 23 | 14 | 37 | 1997 | 26 | 16 | 42 | 1998 | 36 | 14 | 50 | 1999 | 30 | 20 | 50 | 2000 | 15 | 12 | 27 | 2001 | 20 | 13 | 33 | 2002 | 9 | 7 | 16 | 2003 | 20 | 8 | 28 | 2004 | 16 | 16 | 32 | 2005 | 14 | 11 | 25 | 2006 | 23 | 13 | 36 | 2007 | 10 | 15 | 25 | 2008 | 9 | 14 | 23 | 2009 | 12 | 14 | 26 | 2010 | 15 | 13 | 28 | 2011 | 12 | 8 | 20 | 2012 | 14 | 10 | 24 | 2013 | 17 | 17 | 34 | 2014 | 18 | 9 | 27 | 2015 | 6 | 12 | 18 | 2016 | 13 | 9 | 22 | 2017 | 9 | 8 | 17 | 2018 | 8 | 6 | 14 | 2019 | 6 | 9 | 15 | 2020 | 3 | 9 | 12 |
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Below are the most recent publications written about "Immunosuppressive Agents" by people in Profiles.
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Melmed GY, Rubin DT, McGovern DPB. Winter Is Coming! Clinical, Immunologic, and Practical Considerations for Vaccinating Patients With Inflammatory Bowel Disease During the Coronavirus Disease-2019 Pandemic. Gastroenterology. 2021 02; 160(3):639-644.
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Lichtenstein GR, Rubin DT. Coronavirus and Patients With Inflammatory Bowel Disease: Management Strategies for the Practicing Clinician. Am J Gastroenterol. 2020 10; 115(10):1566-1569.
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Cravedi P, Schold JD, Safa K, Kates OS, Elfadawy N, Mannon RB, Shah MB, Hammond SP, Avery R, Guerrero Miranda C, Riella LV, Jowsey-Gregoire S, Akalin E, Camirand G, Alegre ML, Azzi J. The COVID-19 pandemic: A community approach. Clin Transplant. 2020 11; 34(11):e14059.
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Singhvi A, Barghash M, Lala A, Mitter SS, Parikh A, Oliveros E, Rollins BM, Brunjes DL, Alvarez-Garcia J, Johnston E, Ryan K, Itagaki S, Moss N, Pinney SP, Anyanwu A, Mancini D. Challenges in heart transplantation during COVID-19: A single-center experience. J Heart Lung Transplant. 2020 09; 39(9):894-903.
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Rosen MH, Axelrad J, Hudesman D, Rubin DT, Chang S. Management of Acute Severe Ulcerative Colitis in a Pregnant Woman With COVID-19 Infection: A Case Report and Review of the Literature. Inflamm Bowel Dis. 2020 06 18; 26(7):971-973.
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Gerstle K, Siddiqui A, Schulte JJ, Cohn SL. Paraneoplastic opsoclonus myoclonus syndrome associated with inflammatory myofibroblastic tumor in a pediatric patient. Pediatr Blood Cancer. 2020 08; 67(8):e28218.
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Holzhauser L, Lourenco L, Sarswat N, Kim G, Chung B, Nguyen AB. Early experience of COVID-19 in 2 heart transplant recipients: Case reports and review of treatment options. Am J Transplant. 2020 10; 20(10):2916-2922.
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He Y, Zuo C, Jia D, Bai P, Kong D, Chen D, Liu G, Li J, Wang Y, Chen G, Yan S, Xiao B, Zhang J, Piao L, Li Y, Deng Y, Li B, Roux PP, Andreasson KI, Breyer RM, Su Y, Wang J, Lyu A, Shen Y, Yu Y. Loss of DP1 Aggravates Vascular Remodeling in Pulmonary Arterial Hypertension via mTORC1 Signaling. Am J Respir Crit Care Med. 2020 05 15; 201(10):1263-1276.
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Wang J, Prenner J, Wang W, Sakuraba A, Hyman N, Dalal S, Hurst R, Cohen RD, Umanskiy K, Shogan BD, Alpert L, Rubin DT, Colwell J, Pekow J. Risk factors and treatment outcomes of peristomal pyoderma gangrenosum in patients with inflammatory bowel disease. Aliment Pharmacol Ther. 2020 06; 51(12):1365-1372.
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Sprague SM. Interventions for Preventing Bone Disease Following Kidney Transplantation: Is There Evidence for Specific Therapy? Am J Kidney Dis. 2020 05; 75(5):809-811.
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