 Ergosterol
"Ergosterol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in ERGOCALCIFEROL.
| Descriptor ID |
D004875
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| MeSH Number(s) |
D04.808.247.222.537 D04.808.247.808.756.287
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| Concept/Terms |
Ergosterol- Ergosterol
- Pro-Vitamin D2
- D2, Pro-Vitamin
- Pro Vitamin D2
- Provitamin D 2
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Below are MeSH descriptors whose meaning is more general than "Ergosterol".
Below are MeSH descriptors whose meaning is more specific than "Ergosterol".
This graph shows the total number of publications written about "Ergosterol" by people in this website by year, and whether "Ergosterol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ergosterol" by people in Profiles.
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Steck TL, Lange Y. Transverse distribution of plasma membrane bilayer cholesterol: Picking sides. Traffic. 2018 10; 19(10):750-760.
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Poklepovich TJ, Rinaldi MA, Tomazic ML, Favale NO, Turkewitz AP, Nudel CB, Nusblat AD. The cytochrome b5 dependent C-5(6) sterol desaturase DES5A from the endoplasmic reticulum of Tetrahymena thermophila complements ergosterol biosynthesis mutants in Saccharomyces cerevisiae. Steroids. 2012 Nov; 77(13):1313-20.
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Gray KC, Palacios DS, Dailey I, Endo MM, Uno BE, Wilcock BC, Burke MD. Amphotericin primarily kills yeast by simply binding ergosterol. Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7):2234-9.
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Palacios DS, Dailey I, Siebert DM, Wilcock BC, Burke MD. Synthesis-enabled functional group deletions reveal key underpinnings of amphotericin B ion channel and antifungal activities. Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17):6733-8.
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Sargis RM, Subbaiah PV. Protection of membrane cholesterol by sphingomyelin against free radical-mediated oxidation. Free Radic Biol Med. 2006 Jun 15; 40(12):2092-102.
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Rebsamen MC, Sun J, Norman AW, Liao JK. 1alpha,25-dihydroxyvitamin D3 induces vascular smooth muscle cell migration via activation of phosphatidylinositol 3-kinase. Circ Res. 2002 Jul 12; 91(1):17-24.
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