Dithiothreitol
"Dithiothreitol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols.
Descriptor ID |
D004229
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MeSH Number(s) |
D02.033.800.196 D02.886.740.224 D09.853.196
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Concept/Terms |
Dithiothreitol- Dithiothreitol
- Cleland's Reagent
- Clelands Reagent
- Reagent, Cleland's
- Cleland Reagent
- Reagent, Cleland
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Below are MeSH descriptors whose meaning is more general than "Dithiothreitol".
Below are MeSH descriptors whose meaning is more specific than "Dithiothreitol".
This graph shows the total number of publications written about "Dithiothreitol" by people in this website by year, and whether "Dithiothreitol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1982 | 0 | 1 | 1 | 1988 | 0 | 1 | 1 | 1992 | 0 | 1 | 1 | 1993 | 0 | 1 | 1 | 1994 | 0 | 2 | 2 | 1995 | 0 | 2 | 2 | 1997 | 0 | 2 | 2 | 1998 | 0 | 2 | 2 | 2001 | 0 | 1 | 1 | 2003 | 0 | 1 | 1 | 2004 | 0 | 1 | 1 | 2007 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2010 | 0 | 1 | 1 | 2013 | 0 | 1 | 1 | 2016 | 0 | 1 | 1 | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dithiothreitol" by people in Profiles.
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Wang J, Meade JR, Brown NK, Weidner JG, Marino SR. EDTA is superior to DTT treatment for overcoming the prozone effect in HLA antibody testing. HLA. 2017 02; 89(2):82-89.
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Poellmann MJ, Sosnick TR, Meredith SC, Lee RC. The Pentablock Amphiphilic Copolymer T1107 Prevents Aggregation of Denatured and Reduced Lysozyme. Macromol Biosci. 2017 02; 17(2).
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Parlato M, Johnson A, Hudalla GA, Murphy WL. Adaptable poly(ethylene glycol) microspheres capable of mixed-mode degradation. Acta Biomater. 2013 Dec; 9(12):9270-80.
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McNeer JL, Goussetis DJ, Sassano A, Dolniak B, Kroczynska B, Glaser H, Altman JK, Platanias LC. Arsenic trioxide-dependent activation of thousand-and-one amino acid kinase 2 and transforming growth factor-beta-activated kinase 1. Mol Pharmacol. 2010 May; 77(5):828-35.
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Hudalla GA, Eng TS, Murphy WL. An approach to modulate degradation and mesenchymal stem cell behavior in poly(ethylene glycol) networks. Biomacromolecules. 2008 Mar; 9(3):842-9.
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Maresso AW, Wu R, Kern JW, Zhang R, Janik D, Missiakas DM, Duban ME, Joachimiak A, Schneewind O. Activation of inhibitors by sortase triggers irreversible modification of the active site. J Biol Chem. 2007 Aug 10; 282(32):23129-39.
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Dai Q, Piccirilli JA. Efficient synthesis of 2',3'-dideoxy-2'-amino-3'-thiouridine. Org Lett. 2004 Jun 24; 6(13):2169-72.
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Curcio-Morelli C, Gereben B, Zavacki AM, Kim BW, Huang S, Harney JW, Larsen PR, Bianco AC. In vivo dimerization of types 1, 2, and 3 iodothyronine selenodeiodinases. Endocrinology. 2003 Mar; 144(3):937-46.
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Reeve HL, Tolarova S, Nelson DP, Archer S, Weir EK. Redox control of oxygen sensing in the rabbit ductus arteriosus. J Physiol. 2001 May 15; 533(Pt 1):253-61.
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Qi PX, Sosnick TR, Englander SW. The burst phase in ribonuclease A folding and solvent dependence of the unfolded state. Nat Struct Biol. 1998 Oct; 5(10):882-4.
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