"Thyroxine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
| Descriptor ID |
D013974
|
| MeSH Number(s) |
D06.472.931.812 D12.125.072.050.767
|
| Concept/Terms |
Thyroxine- Thyroxine
- T4 Thyroid Hormone
- Thyroid Hormone, T4
- Thyroxin
- O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine
- L-3,5,3',5'-Tetraiodothyronine
- Levothyroxine
- L-Thyroxine
- L Thyroxine
- 3,5,3',5'-Tetraiodothyronine
- O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine
Levothyroxin Deladande- Levothyroxin Deladande
- Deladande, Levothyroxin
- Levothyroxin Delalande
- Delalande, Levothyroxin
|
Below are MeSH descriptors whose meaning is more general than "Thyroxine".
Below are MeSH descriptors whose meaning is more specific than "Thyroxine".
This graph shows the total number of publications written about "Thyroxine" by people in this website by year, and whether "Thyroxine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1997 | 1 | 3 | 4 |
| 1998 | 1 | 4 | 5 |
| 1999 | 0 | 3 | 3 |
| 2000 | 2 | 7 | 9 |
| 2001 | 0 | 4 | 4 |
| 2002 | 1 | 10 | 11 |
| 2003 | 0 | 5 | 5 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 5 | 6 |
| 2006 | 2 | 3 | 5 |
| 2007 | 1 | 3 | 4 |
| 2008 | 1 | 3 | 4 |
| 2009 | 2 | 3 | 5 |
| 2010 | 2 | 4 | 6 |
| 2011 | 2 | 4 | 6 |
| 2012 | 0 | 4 | 4 |
| 2013 | 3 | 4 | 7 |
| 2014 | 1 | 3 | 4 |
| 2015 | 5 | 3 | 8 |
| 2016 | 2 | 2 | 4 |
| 2017 | 2 | 2 | 4 |
| 2018 | 1 | 4 | 5 |
| 2019 | 3 | 3 | 6 |
| 2020 | 6 | 3 | 9 |
| 2021 | 2 | 3 | 5 |
| 2022 | 4 | 6 | 10 |
| 2023 | 5 | 4 | 9 |
| 2024 | 4 | 3 | 7 |
| 2025 | 5 | 2 | 7 |
| 2026 | 8 | 2 | 10 |
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Below are the most recent publications written about "Thyroxine" by people in Profiles.
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A Longitudinal, Real-World Study of the Relationship between Levothyroxine Dose and Suboptimal Hypothyroidism Treatment. Thyroid. 2026 08; 36(8):832-839.
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A Phase 2 Study of XP-8121: Once-Weekly Subcutaneous Levothyroxine Sodium for the Treatment of Hypothyroidism in Adults. Thyroid. 2026 08; 36(8):853-861.
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Suboptimal Levothyroxine Treatment is Associated with Increases in Mean Blood Pressure and Blood Pressure Variability. J Clin Endocrinol Metab. 2026 May 19; 111(6):e1626-e1633.
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Overnutrition in mice impairs thyroid hormone biosynthesis and utilization, causing hypothyroidism, despite remarkable thyroidal adaptations. J Clin Invest. 2026 Apr 15; 136(8).
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Real or Not Real? An Elevated TSH. J Investig Med High Impact Case Rep. 2026 Jan-Dec; 14:23247096261430087.
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Thyroid Hormone Synthesis Without Thyroglobulin. Thyroid. 2026 04; 36(4):441-450.
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The Incidence of Cardiovascular Disease Events in Women with Hypothyroidism: The Study of Women's Health Across the Nation. Thyroid. 2026 03; 36(3):251-258.
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Treatment of Hypothyroidism That Contains Liothyronine is Associated With Reduced Risk of Dementia and Mortality. J Clin Endocrinol Metab. 2026 Jan 21; 111(2):561-571.
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Measuring Hypothyroidism Disease Control Using a TSH-based "Time-in-range". J Clin Endocrinol Metab. 2026 Jan 21; 111(2):e484-e492.
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Cross-sectional association of arsenic exposure with thyroid function in Bangladeshi children aged 5 to 7 years. Environ Health. 2026 Jan 07; 25(1):9.