 Estradiol
"Estradiol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Generally refers to the 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids. In humans, it is produced primarily by the cyclic ovaries and the PLACENTA. It is also produced by the adipose tissue of men and postmenopausal women. The 17-alpha-isomer of estradiol binds weakly to estrogen receptors (RECEPTORS, ESTROGEN) and exhibits little estrogenic activity in estrogen-responsive tissues. Various isomers can be synthesized.
| Descriptor ID |
D004958
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| MeSH Number(s) |
D04.808.365.415.248 D06.472.334.851.437.500
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| Concept/Terms |
Estradiol- Estradiol
- 17 beta-Oestradiol
- 17 beta Oestradiol
- Estradiol-17beta
- Estradiol 17beta
- Oestradiol
- 17 beta-Estradiol
- 17 beta Estradiol
- Estradiol-17 beta
- Estradiol 17 beta
Ovocyclin- Ovocyclin
- Orion Brand of Estradiol
- Estradiol Orion Brand
Vivelle- Vivelle
- Novartis Pharmaceuticals Brand of Estradiol
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Below are MeSH descriptors whose meaning is more general than "Estradiol".
Below are MeSH descriptors whose meaning is more specific than "Estradiol".
This graph shows the total number of publications written about "Estradiol" by people in this website by year, and whether "Estradiol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 3 | 4 | | 1981 | 2 | 2 | 4 | | 1982 | 0 | 3 | 3 | | 1983 | 2 | 2 | 4 | | 1984 | 3 | 2 | 5 | | 1985 | 1 | 4 | 5 | | 1986 | 2 | 2 | 4 | | 1987 | 0 | 2 | 2 | | 1988 | 3 | 3 | 6 | | 1989 | 1 | 2 | 3 | | 1990 | 0 | 6 | 6 | | 1991 | 0 | 2 | 2 | | 1992 | 4 | 0 | 4 | | 1993 | 2 | 5 | 7 | | 1994 | 1 | 2 | 3 | | 1995 | 1 | 2 | 3 | | 1996 | 2 | 6 | 8 | | 1997 | 3 | 2 | 5 | | 1998 | 4 | 2 | 6 | | 1999 | 2 | 2 | 4 | | 2000 | 4 | 6 | 10 | | 2001 | 1 | 2 | 3 | | 2002 | 2 | 3 | 5 | | 2003 | 8 | 1 | 9 | | 2004 | 0 | 3 | 3 | | 2005 | 3 | 2 | 5 | | 2006 | 1 | 1 | 2 | | 2007 | 4 | 4 | 8 | | 2008 | 0 | 3 | 3 | | 2009 | 6 | 4 | 10 | | 2010 | 1 | 2 | 3 | | 2011 | 2 | 0 | 2 | | 2012 | 1 | 3 | 4 | | 2013 | 1 | 4 | 5 | | 2014 | 0 | 2 | 2 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 2 | 2 | | 2017 | 2 | 1 | 3 | | 2018 | 1 | 2 | 3 |
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Below are the most recent publications written about "Estradiol" by people in Profiles.
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Sharma A, Toy W, Guillen VS, Sharma N, Min J, Carlson KE, Mayne CG, Lin S, Sabio M, Greene G, Katzenellenbogen BS, Chandarlapaty S, Katzenellenbogen JA. Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain. ACS Chem Biol. 2018 12 21; 13(12):3374-3384.
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Grant JE, Chamberlain SR. Salivary sex hormones in adolescent females with trichotillomania. Psychiatry Res. 2018 07; 265:221-223.
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Veetil AT, Jani MS, Krishnan Y. Chemical control over membrane-initiated steroid signaling with a DNA nanocapsule. Proc Natl Acad Sci U S A. 2018 09 18; 115(38):9432-9437.
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Pang RD, Liautaud MM, Kirkpatrick MG, Huh J, Monterosso J, Leventhal AM. Ovarian Hormones and Transdermal Nicotine Administration Independently and Synergistically Suppress Tobacco Withdrawal Symptoms and Smoking Reinstatement in the Human Laboratory. Neuropsychopharmacology. 2018 03; 43(4):828-837.
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McAuley EM, Mustafi D, Simons BW, Valek R, Zamora M, Markiewicz E, Lamperis S, Williams A, Roman BB, Vezina C, Karczmar G, Oto A, Vander Griend DJ. Magnetic Resonance Imaging and Molecular Characterization of a Hormone-Mediated Murine Model of Prostate Enlargement and Bladder Outlet Obstruction. Am J Pathol. 2017 Nov; 187(11):2378-2387.
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Greeley SA, Littlejohn E, Husain AN, Waggoner D, Gundeti M, Rosenfield RL. The Effect of the Testis on the Ovary: Structure-Function Relationships in a Neonate with a Unilateral Ovotestis (Ovotesticular Disorder of Sex Development)?. Horm Res Paediatr. 2017; 87(3):205-212.
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Toy W, Weir H, Razavi P, Lawson M, Goeppert AU, Mazzola AM, Smith A, Wilson J, Morrow C, Wong WL, De Stanchina E, Carlson KE, Martin TS, Uddin S, Li Z, Fanning S, Katzenellenbogen JA, Greene G, Baselga J, Chandarlapaty S. Activating ESR1 Mutations Differentially Affect the Efficacy of ER Antagonists. Cancer Discov. 2017 03; 7(3):277-287.
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Eclov RJ, Kim MJ, Smith RP, Liang X, Ahituv N, Kroetz DL. In Vivo Hepatic Enhancer Elements in the Human ABCG2 Locus. Drug Metab Dispos. 2017 02; 45(2):208-215.
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Carpenter RS, Iwuchukwu I, Hinkson CL, Reitz S, Lee W, Kukino A, Zhang A, Pike MM, Ardelt AA. High-dose estrogen treatment at reperfusion reduces lesion volume and accelerates recovery of sensorimotor function after experimental ischemic stroke. Brain Res. 2016 05 15; 1639:200-13.
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Bellet M, Gray KP, Francis PA, Láng I, Ciruelos E, Lluch A, Climent MA, Catalán G, Avella A, Bohn U, González-Martin A, Ferrer R, Catalán R, Azaro A, Rajasekaran A, Morales J, Vázquez J, Fleming GF, Price KN, Regan MM. Twelve-Month Estrogen Levels in Premenopausal Women With Hormone Receptor-Positive Breast Cancer Receiving Adjuvant Triptorelin Plus Exemestane or Tamoxifen in the Suppression of Ovarian Function Trial (SOFT): The SOFT-EST Substudy. J Clin Oncol. 2016 05 10; 34(14):1584-93.
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