 Exons
"Exons" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The parts of a transcript of a split GENE remaining after the INTRONS are removed. They are spliced together to become a MESSENGER RNA or other functional RNA.
| Descriptor ID |
D005091
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| MeSH Number(s) |
G05.360.340.024.340.137.232
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Exons".
Below are MeSH descriptors whose meaning is more specific than "Exons".
This graph shows the total number of publications written about "Exons" by people in this website by year, and whether "Exons" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 0 | 1 | 1 | | 1988 | 0 | 1 | 1 | | 1989 | 0 | 4 | 4 | | 1990 | 1 | 2 | 3 | | 1991 | 1 | 6 | 7 | | 1992 | 0 | 10 | 10 | | 1993 | 1 | 8 | 9 | | 1994 | 0 | 10 | 10 | | 1995 | 1 | 6 | 7 | | 1996 | 0 | 13 | 13 | | 1997 | 2 | 9 | 11 | | 1998 | 0 | 10 | 10 | | 1999 | 2 | 12 | 14 | | 2000 | 1 | 17 | 18 | | 2001 | 2 | 7 | 9 | | 2002 | 3 | 15 | 18 | | 2003 | 2 | 17 | 19 | | 2004 | 2 | 10 | 12 | | 2005 | 2 | 11 | 13 | | 2006 | 3 | 6 | 9 | | 2007 | 0 | 12 | 12 | | 2008 | 0 | 9 | 9 | | 2009 | 0 | 13 | 13 | | 2010 | 3 | 12 | 15 | | 2011 | 2 | 14 | 16 | | 2012 | 3 | 10 | 13 | | 2013 | 1 | 4 | 5 | | 2014 | 0 | 7 | 7 | | 2015 | 3 | 6 | 9 | | 2016 | 4 | 6 | 10 | | 2017 | 2 | 4 | 6 | | 2018 | 2 | 3 | 5 | | 2019 | 3 | 2 | 5 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Exons" by people in Profiles.
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Salgia R, Sattler M, Scheele J, Stroh C, Felip E. The promise of selective MET inhibitors in non-small cell lung cancer with MET exon 14 skipping. Cancer Treat Rev. 2020 Jul; 87:102022.
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Demonbreun AR, Wyatt EJ, Fallon KS, Oosterbaan CC, Page PG, Hadhazy M, Quattrocelli M, Barefield DY, McNally EM. A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping. Dis Model Mech. 2019 11 04; 13(2).
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Zhou KI, Shi H, Lyu R, Wylder AC, Matuszek Z, Pan JN, He C, Parisien M, Pan T. Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG. Mol Cell. 2019 10 03; 76(1):70-81.e9.
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Osoegawa K, Mallempati KC, Gangavarapu S, Oki A, Gendzekhadze K, Marino SR, Brown NK, Bettinotti MP, Weimer ET, Montero-Martín G, Creary LE, Vayntrub TA, Chang CJ, Askar M, Mack SJ, Fernández-Viña MA. HLA alleles and haplotypes observed in 263 US families. Hum Immunol. 2019 Sep; 80(9):644-660.
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Kohli U, Aziz Z, Beaser AD, Nayak HM. A large deletion in RYR2 exon 3 is associated with nadolol and flecainide refractory catecholaminergic polymorphic ventricular tachycardia. Pacing Clin Electrophysiol. 2019 08; 42(8):1146-1154.
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Fica SM, Oubridge C, Wilkinson ME, Newman AJ, Nagai K. A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation. Science. 2019 02 15; 363(6428):710-714.
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Ritterhouse LL. Targeted RNA Sequencing in Non-Small Cell Lung Cancer. J Mol Diagn. 2019 03; 21(2):183-185.
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Park MJ, Shen H, Kim NH, Gao F, Failor C, Knudtson JF, McLaughlin J, Halder SK, Heikkinen TA, Vahteristo P, Al-Hendy A, Schenken RS, Boyer TG. Mediator Kinase Disruption in MED12-Mutant Uterine Fibroids From Hispanic Women of South Texas. J Clin Endocrinol Metab. 2018 11 01; 103(11):4283-4292.
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Krishnaswamy S, Bukhari I, Mohammed AK, Amer OE, Tripathi G, Alokail MS, Al-Daghri NM. Identification of the splice variants of Recepteur d'Origine nantais (RON) in lung cancer cell lines. Gene. 2018 Dec 30; 679:335-340.
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Wyatt EJ, Demonbreun AR, Kim EY, Puckelwartz MJ, Vo AH, Dellefave-Castillo LM, Gao QQ, Vainzof M, Pavanello RCM, Zatz M, McNally EM. Efficient exon skipping of SGCG mutations mediated by phosphorodiamidate morpholino oligomers. JCI Insight. 2018 05 03; 3(9).
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