Exons
"Exons" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The parts of a transcript of a split GENE remaining after the INTRONS are removed. They are spliced together to become a MESSENGER RNA or other functional RNA.
Descriptor ID |
D005091
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MeSH Number(s) |
G05.360.340.024.340.137.232
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Exons".
Below are MeSH descriptors whose meaning is more specific than "Exons".
This graph shows the total number of publications written about "Exons" by people in this website by year, and whether "Exons" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1987 | 0 | 1 | 1 | 1988 | 0 | 1 | 1 | 1989 | 0 | 4 | 4 | 1990 | 1 | 2 | 3 | 1991 | 1 | 7 | 8 | 1992 | 0 | 10 | 10 | 1993 | 1 | 8 | 9 | 1994 | 0 | 10 | 10 | 1995 | 3 | 6 | 9 | 1996 | 1 | 14 | 15 | 1997 | 3 | 10 | 13 | 1998 | 1 | 11 | 12 | 1999 | 2 | 13 | 15 | 2000 | 1 | 17 | 18 | 2001 | 2 | 8 | 10 | 2002 | 3 | 15 | 18 | 2003 | 2 | 18 | 20 | 2004 | 2 | 10 | 12 | 2005 | 2 | 11 | 13 | 2006 | 3 | 6 | 9 | 2007 | 0 | 12 | 12 | 2008 | 0 | 9 | 9 | 2009 | 0 | 13 | 13 | 2010 | 3 | 13 | 16 | 2011 | 2 | 14 | 16 | 2012 | 3 | 11 | 14 | 2013 | 1 | 4 | 5 | 2014 | 0 | 8 | 8 | 2015 | 3 | 7 | 10 | 2016 | 4 | 6 | 10 | 2017 | 2 | 6 | 8 | 2018 | 2 | 4 | 6 | 2019 | 3 | 2 | 5 | 2020 | 2 | 2 | 4 | 2021 | 2 | 5 | 7 | 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Exons" by people in Profiles.
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Halldorsson BV, Eggertsson HP, Moore KHS, Hauswedell H, Eiriksson O, Ulfarsson MO, Palsson G, Hardarson MT, Oddsson A, Jensson BO, Kristmundsdottir S, Sigurpalsdottir BD, Stefansson OA, Beyter D, Holley G, Tragante V, Gylfason A, Olason PI, Zink F, Asgeirsdottir M, Sverrisson ST, Sigurdsson B, Gudjonsson SA, Sigurdsson GT, Halldorsson GH, Sveinbjornsson G, Norland K, Styrkarsdottir U, Magnusdottir DN, Snorradottir S, Kristinsson K, Sobech E, Jonsson H, Geirsson AJ, Olafsson I, Jonsson P, Pedersen OB, Erikstrup C, Brunak S, Ostrowski SR. The sequences of 150,119 genomes in the UK Biobank. Nature. 2022 07; 607(7920):732-740.
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Le X, Sakai H, Felip E, Veillon R, Garassino MC, Raskin J, Cortot AB, Viteri S, Mazieres J, Smit EF, Thomas M, Iams WT, Cho BC, Kim HR, Yang JC, Chen YM, Patel JD, Bestvina CM, Park K, Griesinger F, Johnson M, Gottfried M, Britschgi C, Heymach J, Sikoglu E, Berghoff K, Schumacher KM, Bruns R, Otto G, Paik PK. Tepotinib Efficacy and Safety in Patients with MET Exon 14 Skipping NSCLC: Outcomes in Patient Subgroups from the VISION Study with Relevance for Clinical Practice. Clin Cancer Res. 2022 03 15; 28(6):1117-1126.
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Le X, Cornelissen R, Garassino M, Clarke JM, Tchekmedyian N, Goldman JW, Leu SY, Bhat G, Lebel F, Heymach JV, Socinski MA. Poziotinib in Non-Small-Cell Lung Cancer Harboring HER2 Exon 20 Insertion Mutations After Prior Therapies: ZENITH20-2 Trial. J Clin Oncol. 2022 03 01; 40(7):710-718.
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Castanza AS, Ramirez S, Tripathi PP, Daza RAM, Kalume FK, Ramirez JM, Hevner RF. AUTS2 Regulates RNA Metabolism and Dentate Gyrus Development in Mice. Cereb Cortex. 2021 08 26; 31(10):4808-4824.
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Zhang X, Zhang CM, Prokopenko D, Liang Y, Zhen SY, Weigle IQ, Han W, Aryal M, Tanzi RE, Sisodia SS. An APP ectodomain mutation outside of the Aß domain promotes Aß production in vitro and deposition in vivo. J Exp Med. 2021 06 07; 218(6).
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Kohli U, Sriram CS, Nayak HM. A novel familial SCN5A exon 20 deletion is associated with a heterogeneous phenotype. J Electrocardiol. 2021 May-Jun; 66:131-135.
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Prelaj A, Bottiglieri A, Proto C, Lo Russo G, Signorelli D, Ferrara R, Galli G, De Toma A, Viscardi G, Brambilla M, Lobefaro R, Nichetti F, Manglaviti S, Occhipinti M, Labianca A, Ganzinelli M, Gallucci R, Zilembo N, Greco GF, Torri V, de Braud F, Garassino MC. Poziotinib for EGFR and HER2 exon 20 insertion mutation in advanced NSCLC: Results from the expanded access program. Eur J Cancer. 2021 05; 149:235-248.
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Lapadat R, Anani WQ, Bensing KM, Aeschlimann J, Vege S, Lomas-Francis C, Westhoff CM, Fadeyi EA, Denomme GA. A pair of S-silencing single nucleotide variants cis-linked on GYPB. Transfusion. 2021 04; 61(4):E34-E36.
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Strittmatter LM, Capitanchik C, Newman AJ, Hallegger M, Norman CM, Fica SM, Oubridge C, Luscombe NM, Ule J, Nagai K. psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation. Nat Commun. 2021 03 05; 12(1):1488.
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Roth KG, Mambetsariev I, Salgia R. Prolonged survival and response to tepotinib in a non-small-cell lung cancer patient with brain metastases harboring MET exon 14 mutation: a research report. Cold Spring Harb Mol Case Stud. 2020 12; 6(6).
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