The University of Chicago Header Logo

Chuan He

TitleProfessor
InstitutionUniversity of Chicago
DepartmentChemistry
AddressChicago IL 60637
Email
vCardDownload vCard

    Collapse Overview 
    Collapse overview
    Chuan He is the John T. Wilson Distinguished Service Professor in the Department of Chemistry and Department of Biochemistry and Molecular Biology at the University of Chicago.He received his B.S. (1994) from the University of Science and Technology of China. He received his Ph. D. degree from Massachusetts Institute of Technology in chemistry in 2000. After being trained as a Damon-Runyon postdoctoral fellow at Harvard University from 2000-2002, he joined the University of Chicago as an Assistant Professor, and was promoted to Associate Professor in 2008, Professor in 2010 and John T. Wilson Distinguished Service Professor in 2014. He is also a member of the Cancer Research Center at the University of Chicago. His research spans a broad range of chemical biology, RNA biology, epigenetics, biochemistry, molecular biology, and genomics. His recent research concerns reversible RNA and DNA methylation in biological regulation. His research group discovered the first RNA demethylase and showed that reversible RNA methylation significantly affects gene expression regulation.
    Collapse webpage

    Collapse Biography 
    Collapse education and training
    University of Sci. & Tech. China, Hefei/ChinaB.S.1994Chemistry
    MIT, CambridgePh.D.2000Chemistry
    Harvard, CambridgePostdoc2002Chemical Biology
    Collapse awards and honors
    2013HHMI Investigator
    2017Paul Marks Prize in Cancer Research
    2019ACS Chemical Biology Lectureship

    Collapse Research 
    Collapse research activities and funding
    RC2DK139552     (KULKARNI, ROHIT N.)Jul 1, 2024 - Jun 30, 2029
    NIH
    Epitranscriptomics in human obesity and type 2 diabetes
    Role: Co-Principal Investigator
    R01HL174477     (XU, MINGJIANG)Jul 1, 2024 - Jun 30, 2028
    NIH
    Critical roles of RNA m5C-MBD6-H2AK119ub deubiquitylation axis in TET2-mediated HSC regulation
    Role: Co-Principal Investigator
    R01HG012780     (PAN, TAO)Sep 22, 2022 - Jun 30, 2026
    NIH
    Targets and functions of the mammalian snoRNAome
    Role: Co-Principal Investigator
    R01HL155909     (HE, CHUAN)Dec 22, 2021 - Nov 30, 2025
    NIH
    Mechanosensitive M7G epitranscriptome in endothelial health and disease
    Role: Principal Investigator
    UC4DK116278     (KULKARNI, ROHIT N.)Sep 20, 2017 - Aug 31, 2021
    NIH
    Interrogation of dynamic RNA modifications in beta cells in type 1 diabetes
    Role: Co-Principal Investigator
    R21AI128469     (HE, CHUAN)Dec 1, 2016 - Nov 30, 2018
    NIH
    RNA methylation and regulatory T cells
    Role: Principal Investigator
    RM1HG008935     (HE, CHUAN)Sep 27, 2016 - Apr 30, 2026
    NIH
    Center for dynamic RNA epitranscriptomes - Renewal
    Role: Principal Investigator
    R01HG008688     (HE, CHUAN)Sep 10, 2015 - Jun 30, 2019
    NIH
    Base-resolution sequencing of m6A in RNA
    Role: Principal Investigator
    R01GM113194     (PAN, TAO)Sep 1, 2015 - Jun 30, 2023
    NIH
    Recognition and mechanism of N6-methyl adenosine modifications
    Role: Co-Principal Investigator
    R21ES025644     (MUTLU, GOKHAN M.)May 1, 2015 - Apr 30, 2017
    NIH
    Regulation of IL-6 and DNA and RNA methylation by PM-induced mitochondrial ROS
    Role: Co-Principal Investigator
    R21CA173297     (COHN, SUSAN L.)Jul 1, 2013 - Jun 30, 2015
    NIH
    Mechanisms of Pancreatic Cancer Inhibition by SPARC
    Role: Co-Principal Investigator
    R21NS080120     (COHN, SUSAN L.)Mar 1, 2013 - Feb 28, 2015
    NIH
    Mechanism of SPARC peptide FSEC inhibition of angiogenesis in neuroblastoma
    Role: Co-Principal Investigator
    R01HG006827     (HE, CHUAN)Aug 7, 2012 - Jun 30, 2026
    NIH
    Labeling and sequencing of 5hmC and 5mC in DNA-Renewal
    Role: Principal Investigator
    R01GM088599     (PAN, TAO)Aug 1, 2009 - Jul 31, 2014
    NIH
    Discovering the epigenetics of RNA modifications
    Role: Co-Principal Investigator
    R01AI074658     (HE, CHUAN)Jun 1, 2007 - May 31, 2017
    NIH
    Global Cysteine Modifications in Human Pathogens
    Role: Principal Investigator
    R01ES030546     (HE, CHUAN)Aug 1, 2005 - Jan 31, 2024
    NIH
    Direct Oxidative Nucleic Acids Demethylation
    Role: Principal Investigator
    R01GM071440     (HE, CHUAN)Aug 1, 2005 - Feb 28, 2019
    NIH
    Direct Oxidative Nucleic Acids Demethylation
    Role: Principal Investigator
    T32GM008720     (PICCIRILLI, JOSEPH ANTHONY)Jul 1, 1999 - Jun 30, 2021
    NIH
    Predoctoral Training Program in Chemistry and Biology - Renewal 01
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Peng Y, Karpus J, Patel JD, Vokes EE, Garassino MC, Lugtu K, Zhang Z, Zhang W, Chen M, He C, Bestvina CM. Epigenomic exploration of disease status of EGFR-mutated non-small cell lung cancer using plasma cell-free DNA hydroxymethylomes. Cancer Commun (Lond). 2024 Nov 11. PMID: 39527101.
      Citations:    
    2. Wu J, Xiao Y, Liu Y, Wen L, Jin C, Liu S, Paul S, He C, Regev O, Fei J. Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency. Sci Adv. 2024 Oct 18; 10(42):eadp7727. PMID: 39413186; PMCID: PMC11482332.
      Citations: 2     Fields:    Translation:HumansCells
    3. West-Szymanski DC, Zhang Z, Cui XL, Kowitwanich K, Gao L, Deng Z, Dougherty U, Williams C, Merkle S, He C, Zhang W, Bissonnette M. 5-Hydroxymethylated Biomarkers in Cell-Free DNA Predict Occult Colorectal Cancer up to 36 Months Before Diagnosis in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. JCO Precis Oncol. 2024 Oct; 8:e2400277. PMID: 39393034.
      Citations:    Fields:    Translation:Humans
    4. Zou Z, Dou X, Li Y, Zhang Z, Wang J, Gao B, Xiao Y, Wang Y, Zhao L, Sun C, Liu Q, Yu X, Wang H, Hong J, Dai Q, Yang FC, Xu M, He C. RNA m5C oxidation by TET2 regulates chromatin state and leukaemogenesis. Nature. 2024 Oct; 634(8035):986-994. PMID: 39358506; PMCID: PMC11499264.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Bugno J, Wang L, Yu X, Cao X, Wang J, Huang X, Yang K, Piffko A, Chen K, Luo SY, Naccasha E, Hou Y, Fu S, He C, Fu YX, Liang HL, Weichselbaum RR, Bugno J, Wang L, Yu X, Cao X, Wang J, Huang X, Yang K, Piffko A, Chen K, Luo SY, Naccasha E, Hou Y, Fu S, He C, Fu YX, Liang HL, Weichselbaum RR. Targeting the Dendritic Cell-Secreted Immunoregulatory Cytokine CCL22 Alleviates Radioresistance. Clin Cancer Res. 2024 Oct 01; 30(19):4450-4463. PMID: 38691100; PMCID: PMC11444901.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    6. Wen C, Wang L, Piffkó A, Chen D, Yu X, Zawieracz K, Bugno J, Yang K, Naccasha EZ, Ji F, Wang J, Huang X, Luo SY, Tan L, Shen B, Luo C, McNerney ME, Chmura SJ, Arina A, Pitroda SP, He C, Liang H, Weichselbaum RR. YTHDF1 loss in dendritic cells potentiates radiation-induced antitumor immunity via STING-dependent type I IFN production. J Clin Invest. 2024 Sep 26. PMID: 39325547.
      Citations:    Fields:    
    7. Liu C, Dou X, Zhao Y, Zhang L, Zhang L, Dai Q, Liu J, Wu T, Xiao Y, He C. IGF2BP3 promotes mRNA degradation through internal m7G modification. Nat Commun. 2024 Aug 28; 15(1):7421. PMID: 39198433; PMCID: PMC11358264.
      Citations:    Fields:    Translation:HumansAnimalsCells
    8. Bhola M, Abe K, Orozco P, Rahnamoun H, Avila-Lopez P, Taylor E, Muhammad N, Liu B, Patel P, Marko JF, Starner AC, He C, Van Nostrand EL, Mondragón A, Lauberth SM. RNA interacts with topoisomerase I to adjust DNA topology. Mol Cell. 2024 Sep 05; 84(17):3192-3208.e11. PMID: 39173639; PMCID: PMC11380577.
      Citations:    Fields:    Translation:HumansCells
    9. Ross MO, Xie Y, Owyang RC, Ye C, Zbihley ONP, Lyu R, Wu T, Wang P, Karginova O, Olopade OI, Zhao M, He C. PTPN2 copper-sensing relays copper level fluctuations into EGFR/CREB activation and associated CTR1 transcriptional repression. Nat Commun. 2024 Aug 13; 15(1):6947. PMID: 39138174; PMCID: PMC11322707.
      Citations: 2     Fields:    Translation:HumansCells
    10. Lyu R, Gao Y, Wu T, Ye C, Wang P, He C. Quantitative analysis of cis-regulatory elements in transcription with KAS-ATAC-seq. Nat Commun. 2024 Aug 10; 15(1):6852. PMID: 39127768; PMCID: PMC11316786.
      Citations:    Fields:    Translation:HumansAnimalsCells
    11. Shi Z, Wen K, Zou Z, Fu W, Guo K, Sammudin NH, Ruan X, Sullere S, Wang S, Zhang X, Thinakaran G, He C, Zhuang X. YTHDF1 mediates translational control by m6A mRNA methylation in adaptation to environmental challenges. bioRxiv. 2024 Aug 09. PMID: 39149343; PMCID: PMC11326287.
      Citations:    
    12. Kaufman ME, Vayani OR, Moore K, Chlenksi A, Wu T, Lee SM, Desai AV, He C, Cohn SL, Applebaum MA, Kaufman ME, Vayani OR, Moore K, Chlenski A, Wu T, Lee SM, Desai AV, He C, Cohn SL, Applebaum MA. Characterizing Relationships between T-cell Inflammation and Outcomes in Patients with High-Risk Neuroblastoma According to Mesenchymal and Adrenergic Signatures. Cancer Res Commun. 2024 Aug 01; 4(8):2255-2266. PMID: 39099200; PMCID: PMC11350481.
      Citations:    Fields:    Translation:HumansCells
    13. Zhao Y, Ma X, Ye C, Li W, Pajdzik K, Dai Q, Sun HL, He C. Pseudouridine Detection and Quantification Using Bisulfite Incorporation Hindered Ligation. ACS Chem Biol. 2024 Aug 16; 19(8):1813-1819. PMID: 39014961.
      Citations:    Fields:    Translation:Humans
    14. Cui XL, Nie J, Zhu H, Kowitwanich K, Beadell AV, West-Szymanski DC, Zhang Z, Dougherty U, Kwesi A, Deng Z, Li Y, Meng D, Roggin K, Barry T, Owyang R, Fefferman B, Zeng C, Gao L, Zhao CWT, Malina Y, Wei J, Weigert M, Kang W, Goel A, Chiu BC, Bissonnette M, Zhang W, Chen M, He C. LABS: linear amplification-based bisulfite sequencing for ultrasensitive cancer detection from cell-free DNA. Genome Biol. 2024 06 14; 25(1):157. PMID: 38877540; PMCID: PMC11177480.
      Citations:    Fields:    Translation:HumansCells
    15. Wang G, Li H, Ye C, He K, Liu S, Jiang B, Ge R, Gao B, Wei J, Zhao Y, Li A, Zhang D, Zhang J, He C. Quantitative profiling of m6A at single base resolution across the life cycle of rice and Arabidopsis. Nat Commun. 2024 Jun 07; 15(1):4881. PMID: 38849358; PMCID: PMC11161662.
      Citations: 2     Fields:    Translation:AnimalsCells
    16. Kahl M, Xu Z, Arumugam S, Edens B, Fischietti M, Zhu AC, Platanias LC, He C, Zhuang X, Ma YC. m6A RNA methylation regulates mitochondrial function. Hum Mol Genet. 2024 05 18; 33(11):969-980. PMID: 38483349; PMCID: PMC11102592.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    17. Pomaville M, Chennakesavalu M, Wang P, Jiang Z, Sun HL, Ren P, Borchert R, Gupta V, Ye C, Ge R, Zhu Z, Brodnik M, Zhong Y, Moore K, Salwen H, George RE, Krajewska M, Chlenski A, Applebaum MA, He C, Cohn SL. Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation. Cell Rep. 2024 May 28; 43(5):114165. PMID: 38691450; PMCID: PMC11181463.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    18. Zou Z, He C. The YTHDF proteins display distinct cellular functions on m6A-modified RNA. Trends Biochem Sci. 2024 Jul; 49(7):611-621. PMID: 38677920; PMCID: PMC11227416.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    19. Pajdzik K, Lyu R, Dou X, Ye C, Zhang LS, Dai Q, He C. Chemical manipulation of m1A mediates its detection in human tRNA. RNA. 2024 Apr 16; 30(5):548-559. PMID: 38531647; PMCID: PMC11019740.
      Citations:    Fields:    Translation:HumansCells
    20. Weigert M, Cui XL, West-Szymanski D, Yu X, Bilecz AJ, Zhang Z, Dhir R, Kehoe M, Zhang W, He C, Lengyel E. 5-Hydroxymethylcytosine signals in serum are a predictor of chemoresistance in high-grade serous ovarian cancer. Gynecol Oncol. 2024 03; 182:82-90. PMID: 38262243; PMCID: PMC11246748.
      Citations:    Fields:    Translation:Humans
    21. Wu T, Cheng AY, Zhang Y, Xu J, Wu J, Wen L, Li X, Liu B, Dou X, Wang P, Zhang L, Fei J, Li J, Ouyang Z, He C. KARR-seq reveals cellular higher-order RNA structures and RNA-RNA interactions. Nat Biotechnol. 2024 Jan 18. PMID: 38238480; PMCID: PMC11255127.
      Citations: 3     Fields:    
    22. Yang Q, Vafaei S, Falahati A, Khosh A, Bariani MV, Omran MM, Bai T, Siblini H, Ali M, He C, Boyer TG, Al-Hendy A. Bromodomain-Containing Protein 9 Regulates Signaling Pathways and Reprograms the Epigenome in Immortalized Human Uterine Fibroid Cells. Int J Mol Sci. 2024 Jan 11; 25(2). PMID: 38255982; PMCID: PMC10815284.
      Citations: 3     Fields:    Translation:HumansCells
    23. Feng X, Cui X, Zhang LS, Ye C, Wang P, Zhong Y, Wu T, Zheng Z, He C. Sequencing of N6-methyl-deoxyadenosine at single-base resolution across the mammalian genome. Mol Cell. 2024 Feb 01; 84(3):596-610.e6. PMID: 38215754; PMCID: PMC10872247.
      Citations: 1     Fields:    Translation:AnimalsCells
    24. Xiao Y, Chen YM, Zou Z, Ye C, Dou X, Wu J, Liu C, Liu S, Yan H, Wang P, Zeng TB, Liu Q, Fei J, Tang W, He C. Profiling of RNA-binding protein binding sites by in situ reverse transcription-based sequencing. Nat Methods. 2024 Feb; 21(2):247-258. PMID: 38200227; PMCID: PMC10864177.
      Citations: 4     Fields:    Translation:Cells
    25. Dai Q, Ye C, Irkliyenko I, Wang Y, Sun HL, Gao Y, Liu Y, Beadell A, Perea J, Goel A, He C. Ultrafast bisulfite sequencing detection of 5-methylcytosine in DNA and RNA. Nat Biotechnol. 2024 Oct; 42(10):1559-1570. PMID: 38168991; PMCID: PMC11217147.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    26. Jiang B, Zhong Z, Gu L, Zhang X, Wei J, Ye C, Lin G, Qu G, Xiang X, Wen C, Hummel M, Bailey-Serres J, Wang Q, He C, Wang X, Lin C. Author Correction: Light-induced LLPS of the CRY2/SPA1/FIO1 complex regulating mRNA methylation and chlorophyll homeostasis in Arabidopsis. Nat Plants. 2024 Jan; 10(1):192. PMID: 38114759; PMCID: PMC10808055.
      Citations:    Fields:    
    27. Chennakesavalu M, Moore K, Chaves G, Veeravalli S, TerHaar R, Wu T, Lyu R, Chlenski A, He C, Piunti A, Applebaum MA. 5-Hydroxymethylcytosine Profiling of Cell-Free DNA Identifies Bivalent Genes That Are Prognostic of Survival in High-Risk Neuroblastoma. JCO Precis Oncol. 2024 Jan; 8:e2300297. PMID: 38295320; PMCID: PMC10843272.
      Citations: 5     Fields:    Translation:Humans
    28. Zhang LS, Dai Q, He C. Base-Resolution Sequencing Methods for Whole-Transcriptome Quantification of mRNA Modifications. Acc Chem Res. 2024 01 02; 57(1):47-58. PMID: 38079380; PMCID: PMC10765377.
      Citations:    Fields:    Translation:AnimalsCells
    29. Jiang B, Zhong Z, Gu L, Zhang X, Wei J, Ye C, Lin G, Qu G, Xiang X, Wen C, Hummel M, Bailey-Serres J, Wang Q, He C, Wang X, Lin C. Light-induced LLPS of the CRY2/SPA1/FIO1 complex regulating mRNA methylation and chlorophyll homeostasis in Arabidopsis. Nat Plants. 2023 12; 9(12):2042-2058. PMID: 38066290; PMCID: PMC10724061.
      Citations: 5     Fields:    Translation:AnimalsCells
    30. Wang L, Katipally RR, Liang HL, Yang K, Pitroda SP, He C, Weichselbaum RR. RNA m6A methylation and MDSCs: Roles and therapeutic implications for radiotherapy. Med. 2023 Dec 08; 4(12):863-874. PMID: 38070481; PMCID: PMC10751059.
      Citations: 1     Fields:    Translation:HumansCells
    31. He PC, He C. mRNA accessibility within mRNPs as a determinant of gene expression. Trends Biochem Sci. 2024 03; 49(3):199-207. PMID: 38071089; PMCID: PMC10939938.
      Citations: 1     Fields:    Translation:Cells
    32. Zhang LS, Ye C, Ju CW, Gao B, Feng X, Sun HL, Wei J, Yang F, Dai Q, He C. BID-seq for transcriptome-wide quantitative sequencing of mRNA pseudouridine at base resolution. Nat Protoc. 2024 Feb; 19(2):517-538. PMID: 37968414; PMCID: PMC11007761.
      Citations: 5     Fields:    Translation:AnimalsCells
    33. Zou Z, Wei J, Chen Y, Kang Y, Shi H, Yang F, Shi Z, Chen S, Zhou Y, Sepich-Poore C, Zhuang X, Zhou X, Jiang H, Wen Z, Jin P, Luo C, He C. FMRP phosphorylation modulates neuronal translation through YTHDF1. Mol Cell. 2023 Dec 07; 83(23):4304-4317.e8. PMID: 37949069; PMCID: PMC10872974.
      Citations: 21     Fields:    Translation:HumansCells
    34. Ge R, Ye C, Peng Y, Dai Q, Zhao Y, Liu S, Wang P, Hu L, He C. Author Correction: m6A-SAC-seq for quantitative whole transcriptome m6A profiling. Nat Protoc. 2023 Nov; 18(11):3652. PMID: 37349502.
      Citations:    Fields:    
    35. Gao L, Zhang Z, Cui XL, West-Szymanski D, Ye C, He C, Zhang W, Bissonnette M. Analysis of genome-wide 5-hydroxymethylation of blood samples stored in different anticoagulants: opportunities for the expansion of clinical resources for epigenetic research. Epigenetics. 2023 12; 18(1):2271692. PMID: 37898998; PMCID: PMC10627064.
      Citations:    Fields:    Translation:HumansCells
    36. Vayani OR, Kaufman ME, Moore K, Chennakesavalu M, TerHaar R, Chaves G, Chlenski A, He C, Cohn SL, Applebaum MA. Adrenergic and mesenchymal signatures are identifiable in cell-free DNA and correlate with metastatic disease burden in children with neuroblastoma. Pediatr Blood Cancer. 2024 Jan; 71(1):e30735. PMID: 37859597; PMCID: PMC10842006.
      Citations: 1     Fields:    Translation:Humans
    37. Dou X, Huang L, Xiao Y, Liu C, Li Y, Zhang X, Yu L, Zhao R, Yang L, Chen C, Yu X, Gao B, Qi M, Gao Y, Shen B, Sun S, He C, Liu J. METTL14 is a chromatin regulator independent of its RNA N6-methyladenosine methyltransferase activity. Protein Cell. 2023 09 14; 14(9):683-697. PMID: 37030005; PMCID: PMC10501186.
      Citations: 12     Fields:    Translation:AnimalsCells
    38. Lyu R, Wu T, Park G, He YY, Chen M, He C. KAS-Analyzer: a novel computational framework for exploring KAS-seq data. Bioinform Adv. 2023; 3(1):vbad121. PMID: 37745002; PMCID: PMC10516523.
      Citations:    
    39. Zhang LS, Ju CW, Jiang B, He C. Base-resolution quantitative DAMM-seq for mapping RNA methylations in tRNA and mitochondrial polycistronic RNA. Methods Enzymol. 2023; 692:39-54. PMID: 37925186; PMCID: PMC10882886.
      Citations:    Fields:    Translation:HumansCells
    40. Dou X, Xiao Y, Shen C, Wang K, Wu T, Liu C, Li Y, Yu X, Liu J, Dai Q, Pajdzik K, Ye C, Ge R, Gao B, Yu J, Sun S, Chen M, Chen J, He C. RBFOX2 recognizes N6-methyladenosine to suppress transcription and block myeloid leukaemia differentiation. Nat Cell Biol. 2023 09; 25(9):1359-1368. PMID: 37640841; PMCID: PMC10495261.
      Citations: 19     Fields:    Translation:HumansCells
    41. Wu T, He C. 6mA-METL-9 axis regulates innate immunity in C. elegans. Cell Res. 2023 08; 33(8):581-582. PMID: 37337028; PMCID: PMC10397307.
      Citations:    Fields:    Translation:AnimalsCells
    42. Zhang L, Dou X, Zheng Z, Ye C, Lu TX, Liang HL, Wang L, Weichselbaum RR, He C. YTHDF2/m6 A/NF-?B axis controls anti-tumor immunity by regulating intratumoral Tregs. EMBO J. 2023 08 01; 42(15):e113126. PMID: 37345898; PMCID: PMC10390869.
      Citations: 12     Fields:    Translation:AnimalsCells
    43. Chen L, Zhang LS, Ye C, Zhou H, Liu B, Gao B, Deng Z, Zhao C, He C, Dickinson BC. Nm-Mut-seq: a base-resolution quantitative method for mapping transcriptome-wide 2'-O-methylation. Cell Res. 2023 09; 33(9):727-730. PMID: 37316584; PMCID: PMC10474006.
      Citations: 6     Fields:    Translation:HumansCells
    44. Cai Q, Zhang Z, Cui X, Zeng C, Cai J, Cai J, Wu K, Zhang X, Shi Y, Arvanitakis Z, Bissonnette MA, Chiu BC, Cheng SY, He C, Zhang W. PETCH-DB: a Portal for Exploring Tissue-specific and Complex disease-associated 5-Hydroxymethylcytosines. Database (Oxford). 2023 06 10; 2023. PMID: 37387524; PMCID: PMC10311472.
      Citations: 2     Fields:    Translation:Humans
    45. Cai Q, Zhang Z, Cui X, Zeng C, Cai J, Cai J, Wu K, Zhang X, Shi Y, Arvanitakis Z, Bissonnette MA, Chiu BC, Cheng SY, He C, Zhang W. PETCH-DB: a Portal for Exploring Tissue-specific and Complex disease-associated 5-Hydroxymethylcytosines. Database (Oxford). 2023 06 10; 2023. PMID: 37387525.
      Citations: 1     Fields:    Translation:Humans
    46. Wang L, Dou X, Chen S, Yu X, Huang X, Zhang L, Chen Y, Wang J, Yang K, Bugno J, Pitroda S, Ding X, Piffko A, Si W, Chen C, Jiang H, Zhou B, Chmura SJ, Luo C, Liang HL, He C, Weichselbaum RR. YTHDF2 inhibition potentiates radiotherapy antitumor efficacy. Cancer Cell. 2023 07 10; 41(7):1294-1308.e8. PMID: 37236197; PMCID: PMC10524856.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    47. He C, Pomaville MM. Advances in targeting RNA modifications for anticancer therapy. Trends Cancer. 2023 07; 9(7):528-542. PMID: 37147166; PMCID: PMC10330282.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    48. Zou Z, He C. Splice epitranscriptomics and DNA damage repair together: ALKBH5-m6A-SF3B1 regulation in leukemic transformation. Mol Cell. 2023 04 06; 83(7):1022-1023. PMID: 37028412.
      Citations:    Fields:    Translation:Cells
    49. Xie J, Zheng Z, Liu X, Zhang N, Choi S, He C, Dong G. Asymmetric Total Synthesis of (+)-Phainanoid A and Biological Evaluation of the Natural Product and Its Synthetic Analogues. J Am Chem Soc. 2023 03 01; 145(8):4828-4852. PMID: 36799470.
      Citations:    Fields:    
    50. Feng X, He C. Mammalian DNA N6-methyladenosine: Challenges and new insights. Mol Cell. 2023 02 02; 83(3):343-351. PMID: 36736309; PMCID: PMC10182828.
      Citations: 4     Fields:    Translation:AnimalsCells
    51. He PC, Wei J, Dou X, Harada BT, Zhang Z, Ge R, Liu C, Zhang LS, Yu X, Wang S, Lyu R, Zou Z, Chen M, He C. Exon architecture controls mRNA m6A suppression and gene expression. Science. 2023 02 17; 379(6633):677-682. PMID: 36705538; PMCID: PMC9990141.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    52. Zou Z, Sepich-Poore C, Zhou X, Wei J, He C. The mechanism underlying redundant functions of the YTHDF proteins. Genome Biol. 2023 01 24; 24(1):17. PMID: 36694229; PMCID: PMC9872407.
      Citations: 31     Fields:    Translation:Humans
    53. Xiao YL, Liu S, Ge R, Wu Y, He C, Chen M, Tang W. Transcriptome-wide profiling and quantification of N6-methyladenosine by enzyme-assisted adenosine deamination. Nat Biotechnol. 2023 Jul; 41(7):993-1003. PMID: 36593412; PMCID: PMC10625715.
      Citations: 41     Fields:    Translation:AnimalsCells
    54. Beadell AV, Zhang Z, Capuano AW, Bennett DA, He C, Zhang W, Arvanitakis Z. Genome-Wide Mapping Implicates 5-Hydroxymethylcytosines in Diabetes Mellitus and Alzheimer's Disease. J Alzheimers Dis. 2023; 93(3):1135-1151. PMID: 37182870; PMCID: PMC10490934.
      Citations: 4     Fields:    Translation:HumansCells
    55. Hu L, Liu S, Peng Y, Ge R, Su R, Senevirathne C, Harada BT, Dai Q, Wei J, Zhang L, Hao Z, Luo L, Wang H, Wang Y, Luo M, Chen M, Chen J, He C. Author Correction: m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome. Nat Biotechnol. 2023 Jan; 41(1):150. PMID: 36450851.
      Citations: 1     Fields:    
    56. Zhang LS, Dai Q, He C. BID-seq: The Quantitative and Base-Resolution Sequencing Method for RNA Pseudouridine. ACS Chem Biol. 2023 01 20; 18(1):4-6. PMID: 36525588.
      Citations: 3     Fields:    Translation:Cells
    57. Zou Z, Wei J, He C. New horizons of regulatory RNA. Fundam Res. 2023 Sep; 3(5):760-762. PMID: 38933289; PMCID: PMC11197478.
      Citations: 1     
    58. Wu T, Lyu R, He C. spKAS-seq reveals R-loop dynamics using low-input materials by detecting single-stranded DNA with strand specificity. Sci Adv. 2022 12 02; 8(48):eabq2166. PMID: 36449625; PMCID: PMC9710868.
      Citations: 7     Fields:    Translation:HumansCells
    59. Ge R, Ye C, Peng Y, Dai Q, Zhao Y, Liu S, Wang P, Hu L, He C. m6A-SAC-seq for quantitative whole transcriptome m6A profiling. Nat Protoc. 2023 02; 18(2):626-657. PMID: 36434097; PMCID: PMC9918705.
      Citations: 13     Fields:    Translation:AnimalsCells
    60. Zhang LS, Ju CW, Liu C, Wei J, Dai Q, Chen L, Ye C, He C. m7G-quant-seq: Quantitative Detection of RNA Internal N7-Methylguanosine. ACS Chem Biol. 2022 12 16; 17(12):3306-3312. PMID: 36398936; PMCID: PMC9764283.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    61. Dai Q, Zhang LS, Sun HL, Pajdzik K, Yang L, Ye C, Ju CW, Liu S, Wang Y, Zheng Z, Zhang L, Harada BT, Dou X, Irkliyenko I, Feng X, Zhang W, Pan T, He C. Quantitative sequencing using BID-seq uncovers abundant pseudouridines in mammalian mRNA at base resolution. Nat Biotechnol. 2023 03; 41(3):344-354. PMID: 36302989; PMCID: PMC10017504.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    62. Zhang L, He C. Ex vivo gliadin stimulation of intestinal cells. Methods Cell Biol. 2023; 179:13-20. PMID: 37625871.
      Citations:    Fields:    Translation:HumansCells
    63. Peng Y, Meng H, Ge R, Liu S, Chen M, He C, Hu L. Detection of m6A RNA modifications at single-nucleotide resolution using m6A-selective allyl chemical labeling and sequencing. STAR Protoc. 2022 12 16; 3(4):101677. PMID: 36112507; PMCID: PMC9485529.
      Citations: 1     Fields:    Translation:Cells
    64. Chiu BC, Zhang Z, Derman BA, Karpus J, Luo L, Zhang S, Langerman SS, Sukhanova M, Bhatti P, Jakubowiak A, He C, Zhang W. Genome-wide profiling of 5-hydroxymethylcytosines in circulating cell-free DNA reveals population-specific pathways in the development of multiple myeloma. J Hematol Oncol. 2022 08 16; 15(1):106. PMID: 35974364; PMCID: PMC9380317.
      Citations: 5     Fields:    Translation:Humans
    65. Du J, Sarkar R, Li Y, He L, Kang W, Liao W, Liu W, Nguyen T, Zhang L, Deng Z, Dougherty U, Kupfer SS, Chen M, Pekow J, Bissonnette M, He C, Li YC. N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis. Dev Cell. 2022 08 22; 57(16):1976-1994.e8. PMID: 35917813; PMCID: PMC9398964.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    66. Liu H, Zeng T, He C, Rawal VH, Zhou H, Dickinson BC. Development of Mild Chemical Catalysis Conditions for m1A-to-m6A Rearrangement on RNA. ACS Chem Biol. 2022 06 17; 17(6):1334-1342. PMID: 35593877; PMCID: PMC9238441.
      Citations: 3     Fields:    Translation:HumansCells
    67. Wei J, Yu X, Yang L, Liu X, Gao B, Huang B, Dou X, Liu J, Zou Z, Cui XL, Zhang LS, Zhao X, Liu Q, He PC, Sepich-Poore C, Zhong N, Liu W, Li Y, Kou X, Zhao Y, Wu Y, Cheng X, Chen C, An Y, Dong X, Wang H, Shu Q, Hao Z, Duan T, He YY, Li X, Gao S, Gao Y, He C. FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development. Science. 2022 05 27; 376(6596):968-973. PMID: 35511947; PMCID: PMC9746489.
      Citations: 86     Fields:    Translation:AnimalsCells
    68. Hu L, Liu S, Peng Y, Ge R, Su R, Senevirathne C, Harada BT, Dai Q, Wei J, Zhang L, Hao Z, Luo L, Wang H, Wang Y, Luo M, Chen M, Chen J, He C. m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome. Nat Biotechnol. 2022 08; 40(8):1210-1219. PMID: 35288668; PMCID: PMC9378555.
      Citations: 101     Fields:    Translation:HumansAnimalsCells
    69. Hsu PJ, Singh K, Dhiman A, Witmer HDD, He C, Eng OS, Catenacci DVT, Posner MC, Turaga KK. Utility of Perioperative Measurement of Cell-Free DNA and Circulating Tumor DNA in Informing the Prognosis of GI Cancers: A Systematic Review. JCO Precis Oncol. 2022 02; 6:e2100337. PMID: 35188804; PMCID: PMC8984241.
      Citations: 2     Fields:    Translation:Humans
    70. He C. ACS Chemical Biology-2022 Editorial Statement. ACS Chem Biol. 2022 01 21; 17(1):1. PMID: 35057625.
      Citations:    Fields:    
    71. Sepich-Poore C, Zheng Z, Schmitt E, Wen K, Zhang ZS, Cui XL, Dai Q, Zhu AC, Zhang L, Sanchez Castillo A, Tan H, Peng J, Zhuang X, He C, Nachtergaele S. The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation. J Biol Chem. 2022 03; 298(3):101590. PMID: 35033535; PMCID: PMC8857481.
      Citations: 25     Fields:    Translation:AnimalsCells
    72. Lyu R, Wu T, Zhu AC, West-Szymanski DC, Weng X, Chen M, He C. KAS-seq: genome-wide sequencing of single-stranded DNA by N3-kethoxal-assisted labeling. Nat Protoc. 2022 Feb; 17(2):402-420. PMID: 35013616; PMCID: PMC8923001.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    73. Wei J, Harada BT, Lu D, Ma R, Gao B, Xu Y, Montauti E, Mani N, Chaudhuri SM, Gregory S, Weinberg SE, Zhang DD, Green R, He C, Fang D. HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease. Mol Cell. 2021 12 16; 81(24):5052-5065.e6. PMID: 34847358; PMCID: PMC8751812.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    74. Yang Z, Yang S, Cui YH, Wei J, Shah P, Park G, Cui X, He C, He YY. METTL14 facilitates global genome repair and suppresses skin tumorigenesis. Proc Natl Acad Sci U S A. 2021 08 31; 118(35). PMID: 34452996; PMCID: PMC8536359.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    75. Terajima H, Lu M, Zhang L, Cui Q, Shi Y, Li J, He C. N6-methyladenosine promotes induction of ADAR1-mediated A-to-I RNA editing to suppress aberrant antiviral innate immune responses. PLoS Biol. 2021 07; 19(7):e3001292. PMID: 34324489; PMCID: PMC8320976.
      Citations: 12     Fields:    
    76. Zhang LS, Xiong QP, Liu C, Wei J, Le C, Zhang L, Harada BT, Dai Q, Feng X, Hao Z, Wang Y, Dong X, Hu L, Wang ED, Pan T, Klungland A, Liu RJ, He C, Peña Perez S. ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing. Nat Cell Biol. 2021 07; 23(7):684-691. PMID: 34253897; PMCID: PMC8716185.
      Citations: 39     Fields:    Translation:HumansCells
    77. Cui YH, Yang S, Wei J, Shea CR, Zhong W, Wang F, Shah P, Kibriya MG, Cui X, Ahsan H, He C, He YY. Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Nat Commun. 2021 04 12; 12(1):2183. PMID: 33846348; PMCID: PMC8041927.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    78. Lee J, Wu Y, Harada BT, Li Y, Zhao J, He C, Ma Y, Wu X. N6 -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness. EMBO J. 2021 04 15; 40(8):e106276. PMID: 33729590; PMCID: PMC8047438.
      Citations: 28     Fields:    Translation:AnimalsCells
    79. Wei J, He C. Chromatin and transcriptional regulation by reversible RNA methylation. Curr Opin Cell Biol. 2021 06; 70:109-115. PMID: 33706173; PMCID: PMC8119380.
      Citations: 36     Fields:    Translation:HumansCells
    80. Chiu BC, Chen C, You Q, Chiu R, Venkataraman G, Zeng C, Zhang Z, Cui X, Smith SM, He C, Zhang W. Alterations of 5-hydroxymethylation in circulating cell-free DNA reflect molecular distinctions of subtypes of non-Hodgkin lymphoma. NPJ Genom Med. 2021 Feb 11; 6(1):11. PMID: 33574286; PMCID: PMC7878492.
      Citations: 8     
    81. He PC, He C. m6 A RNA methylation: from mechanisms to therapeutic potential. EMBO J. 2021 02 01; 40(3):e105977. PMID: 33470439; PMCID: PMC7849164.
      Citations: 257     Fields:    Translation:HumansAnimalsCells
    82. Zhang LS, Liu C, He C. Transcriptome-Wide Detection of Internal N7-Methylguanosine. Methods Mol Biol. 2021; 2298:97-104. PMID: 34085240.
      Citations: 4     Fields:    Translation:HumansCells
    83. Cui XL, Nie J, Ku J, Dougherty U, West-Szymanski DC, Collin F, Ellison CK, Sieh L, Ning Y, Deng Z, Zhao CWT, Bergamaschi A, Pekow J, Wei J, Beadell AV, Zhang Z, Sharma G, Talwar R, Arensdorf P, Karpus J, Goel A, Bissonnette M, Zhang W, Levy S, He C. A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation. Nat Commun. 2020 12 02; 11(1):6161. PMID: 33268789; PMCID: PMC7710742.
      Citations: 68     Fields:    Translation:HumansCells
    84. Du J, Liao W, Liu W, Deb DK, He L, Hsu PJ, Nguyen T, Zhang L, Bissonnette M, He C, Li YC. N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation. Dev Cell. 2020 12 21; 55(6):737-753.e7. PMID: 33220174; PMCID: PMC7755741.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    85. Sun HL, Zhu AC, Gao Y, Terajima H, Fei Q, Liu S, Zhang L, Zhang Z, Harada BT, He YY, Bissonnette MB, Hung MC, He C. Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation. Mol Cell. 2020 11 19; 80(4):633-647.e7. PMID: 33217317; PMCID: PMC7720844.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    86. Zhu AC, He C. Global Detection of RNA Methylation by Click Degradation. ACS Cent Sci. 2020 Dec 23; 6(12):2126-2129. PMID: 33376774; PMCID: PMC7760061.
      Citations:    
    87. Wang Y, Zhang Z, Sepich-Poore C, Zhang L, Xiao Y, He C. LEAD-m6 A-seq for Locus-Specific Detection of N6 -Methyladenosine and Quantification of Differential Methylation. Angew Chem Int Ed Engl. 2021 01 11; 60(2):873-880. PMID: 32970916; PMCID: PMC7902341.
      Citations: 7     Fields:    Translation:Cells
    88. You Q, Cheng AY, Gu X, Harada BT, Yu M, Wu T, Ren B, Ouyang Z, He C. Direct DNA crosslinking with CAP-C uncovers transcription-dependent chromatin organization at high resolution. Nat Biotechnol. 2021 02; 39(2):225-235. PMID: 32839564; PMCID: PMC8274026.
      Citations: 22     Fields:    Translation:AnimalsCells
    89. Lu TX, Zheng Z, Zhang L, Sun HL, Bissonnette M, Huang H, He C. A New Model of Spontaneous Colitis in Mice Induced by Deletion of an RNA m6A Methyltransferase Component METTL14 in T Cells. Cell Mol Gastroenterol Hepatol. 2020; 10(4):747-761. PMID: 32634481; PMCID: PMC7498954.
      Citations: 60     Fields:    Translation:AnimalsCells
    90. Wu T, Lyu R, You Q, He C. Author Correction: Kethoxal-assisted single-stranded DNA sequencing captures global transcription dynamics and enhancer activity in situ. Nat Methods. 2020 Jul; 17(7):749. PMID: 32475983.
      Citations: 1     Fields:    
    91. Zheng Z, Zhang L, Cui XL, Yu X, Hsu PJ, Lyu R, Tan H, Mandal M, Zhang M, Sun HL, Sanchez Castillo A, Peng J, Clark MR, He C, Huang H. Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation. Cell Rep. 2020 06 30; 31(13):107819. PMID: 32610122; PMCID: PMC7371152.
      Citations: 59     Fields:    Translation:AnimalsCells
    92. Zhang Z, Luo K, Zou Z, Qiu M, Tian J, Sieh L, Shi H, Zou Y, Wang G, Morrison J, Zhu AC, Qiao M, Li Z, Stephens M, He X, He C. Genetic analyses support the contribution of mRNA N6-methyladenosine (m6A) modification to human disease heritability. Nat Genet. 2020 09; 52(9):939-949. PMID: 32601472; PMCID: PMC7483307.
      Citations: 83     Fields:    Translation:HumansCells
    93. Liu S, Zhu A, He C, Chen M. REPIC: a database for exploring the N6-methyladenosine methylome. Genome Biol. 2020 04 28; 21(1):100. PMID: 32345346; PMCID: PMC7187508.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    94. Fei Q, Zou Z, Roundtree IA, Sun HL, He C. YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators. PLoS Biol. 2020 04; 18(4):e3000664. PMID: 32267835; PMCID: PMC7170294.
      Citations: 33     Fields:    Translation:HumansCells
    95. Wu T, Lyu R, You Q, He C. Kethoxal-assisted single-stranded DNA sequencing captures global transcription dynamics and enhancer activity in situ. Nat Methods. 2020 05; 17(5):515-523. PMID: 32251394; PMCID: PMC7205578.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    96. Hao Z, Wu T, Cui X, Zhu P, Tan C, Dou X, Hsu KW, Lin YT, Peng PH, Zhang LS, Gao Y, Hu L, Sun HL, Zhu A, Liu J, Wu KJ, He C. N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA. Mol Cell. 2020 05 07; 78(3):382-395.e8. PMID: 32183942; PMCID: PMC7214128.
      Citations: 96     Fields:    Translation:HumansAnimalsCells
    97. Liu C, Cui X, Zhao BS, Narkhede P, Gao Y, Liu J, Dou X, Dai Q, Zhang LS, He C. DNA 5-Methylcytosine-Specific Amplification and Sequencing. J Am Chem Soc. 2020 03 11; 142(10):4539-4543. PMID: 32077696; PMCID: PMC7216556.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    98. Weng X, Gong J, Chen Y, Wu T, Wang F, Yang S, Yuan Y, Luo G, Chen K, Hu L, Ma H, Wang P, Zhang QC, Zhou X, He C. Keth-seq for transcriptome-wide RNA structure mapping. Nat Chem Biol. 2020 05; 16(5):489-492. PMID: 32015521; PMCID: PMC7182492.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    99. Liu J, Dou X, Chen C, Chen C, Liu C, Xu MM, Zhao S, Shen B, Gao Y, Han D, He C. N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription. Science. 2020 01 31; 367(6477):580-586. PMID: 31949099; PMCID: PMC7213019.
      Citations: 286     Fields:    Translation:AnimalsCells
    100. Xu H, Dzhashiashvili Y, Shah A, Kunjamma RB, Weng YL, Elbaz B, Fei Q, Jones JS, Li YI, Zhuang X, Ming GL, He C, Popko B. m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination. Neuron. 2020 01 22; 105(2):293-309.e5. PMID: 31901304; PMCID: PMC7137581.
      Citations: 76     Fields:    Translation:AnimalsCells
    101. Zhang Z, Zhan Q, Eckert M, Zhu A, Chryplewicz A, De Jesus DF, Ren D, Kulkarni RN, Lengyel E, He C, Chen M. RADAR: differential analysis of MeRIP-seq data with a random effect model. Genome Biol. 2019 12 23; 20(1):294. PMID: 31870409; PMCID: PMC6927177.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    102. Applebaum MA, Barr EK, Karpus J, West-Szymanski DC, Oliva M, Sokol EA, Zhang S, Zhang Z, Zhang W, Chlenski A, Salwen HR, Wilkinson E, Dobratic M, Grossman RL, Godley LA, Stranger BE, He C, Cohn SL. 5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma. Clin Cancer Res. 2020 03 15; 26(6):1309-1317. PMID: 31852832; PMCID: PMC7073281.
      Citations: 16     Fields:    Translation:HumansCells
    103. Hsu PJ, Shi H, Zhu AC, Lu Z, Miller N, Edens BM, Ma YC, He C. The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs. J Biol Chem. 2019 12 27; 294(52):19889-19895. PMID: 31753916; PMCID: PMC6937581.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    104. Chiu BC, Zhang Z, You Q, Zeng C, Stepniak E, Bracci PM, Yu K, Venkataraman G, Smith SM, He C, Zhang W. Prognostic implications of 5-hydroxymethylcytosines from circulating cell-free DNA in diffuse large B-cell lymphoma. Blood Adv. 2019 10 08; 3(19):2790-2799. PMID: 31570490; PMCID: PMC6784517.
      Citations: 24     Fields:    Translation:Humans
    105. Zhou H, Rauch S, Dai Q, Cui X, Zhang Z, Nachtergaele S, Sepich C, He C, Dickinson BC. Evolution of a reverse transcriptase to map N1-methyladenosine in human messenger RNA. Nat Methods. 2019 12; 16(12):1281-1288. PMID: 31548705; PMCID: PMC6884687.
      Citations: 83     Fields:    Translation:HumansCells
    106. Wei J, He C. Site-specific m6A editing. Nat Chem Biol. 2019 09; 15(9):848-849. PMID: 31383973.
      Citations: 11     Fields:    Translation:Cells
    107. Zhou KI, Shi H, Lyu R, Wylder AC, Matuszek Z, Pan JN, He C, Pan T, Parisien M. Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG. Mol Cell. 2019 10 03; 76(1):70-81.e9. PMID: 31445886; PMCID: PMC6778029.
      Citations: 197     Fields:    Translation:HumansCells
    108. Zhao S, Liu J, Nanga P, Liu Y, Cicek AE, Knoblauch N, He C, Stephens M, He X. Detailed modeling of positive selection improves detection of cancer driver genes. Nat Commun. 2019 07 30; 10(1):3399. PMID: 31363082; PMCID: PMC6667447.
      Citations: 38     Fields:    Translation:Humans
    109. Edens BM, Vissers C, Su J, Arumugam S, Xu Z, Shi H, Miller N, Ming GL, He C, Song H, Ma YC, Rojas Ringeling F. FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export. Cell Rep. 2019 07 23; 28(4):845-854.e5. PMID: 31340148; PMCID: PMC6687293.
      Citations: 134     Fields:    Translation:AnimalsCells
    110. Yang S, Wei J, Cui YH, Park G, Shah P, Deng Y, Aplin AE, Lu Z, Hwang S, He C, He YY. m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. Nat Commun. 2019 06 25; 10(1):2782. PMID: 31239444; PMCID: PMC6592937.
      Citations: 364     Fields:    Translation:HumansAnimalsCells
    111. Hu L, Liu Y, Han S, Yang L, Cui X, Gao Y, Dai Q, Lu X, Kou X, Zhao Y, Sheng W, Gao S, He X, He C. Jump-seq: Genome-Wide Capture and Amplification of 5-Hydroxymethylcytosine Sites. J Am Chem Soc. 2019 06 05; 141(22):8694-8697. PMID: 31117646; PMCID: PMC7061342.
      Citations: 15     Fields:    
    112. Applebaum MA, Barr EK, Karpus J, Nie J, Zhang Z, Armstrong AE, Uppal S, Sukhanova M, Zhang W, Chlenski A, Salwen HR, Wilkinson E, Dobratic M, Grossman R, Godley LA, Stranger BE, He C, Cohn SL. 5-Hydroxymethylcytosine Profiles Are Prognostic of Outcome in Neuroblastoma and Reveal Transcriptional Networks That Correlate With Tumor Phenotype. JCO Precis Oncol. 2019; 3. PMID: 31179414; PMCID: PMC6553657.
      Citations: 14     Fields:    
    113. Shi H, Wei J, He C. Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers. Mol Cell. 2019 05 16; 74(4):640-650. PMID: 31100245; PMCID: PMC6527355.
      Citations: 744     Fields:    Translation:Cells
    114. Liu J, Luo G, Sun J, Men L, Ye H, He C, Ren D. METTL14 is essential for ß-cell survival and insulin secretion. Biochim Biophys Acta Mol Basis Dis. 2019 09 01; 1865(9):2138-2148. PMID: 31029827.
      Citations: 34     Fields:    Translation:AnimalsCells
    115. Zhang LS, Liu C, Ma H, Dai Q, Sun HL, Luo G, Zhang Z, Zhang L, Hu L, Dong X, He C. Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA. Mol Cell. 2019 06 20; 74(6):1304-1316.e8. PMID: 31031084; PMCID: PMC6588483.
      Citations: 203     Fields:    Translation:HumansAnimalsCells
    116. Jeong JJ, Gu X, Nie J, Sundaravel S, Liu H, Kuo WL, Bhagat TD, Pradhan K, Cao J, Nischal S, McGraw KL, Bhattacharyya S, Bishop MR, Artz A, Thirman MJ, Moliterno A, Ji P, Levine RL, Godley LA, Steidl U, Bieker JJ, List AF, Saunthararajah Y, He C, Verma A, Wickrema A. Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis. Cancer Discov. 2019 06; 9(6):778-795. PMID: 30944118; PMCID: PMC6697164.
      Citations: 29     Fields:    Translation:HumansCells
    117. Liu J, Harada BT, He C. Regulation of Gene Expression by N6-methyladenosine in Cancer. Trends Cell Biol. 2019 06; 29(6):487-499. PMID: 30940398; PMCID: PMC6527461.
      Citations: 112     Fields:    Translation:HumansAnimals
    118. Karginova O, Weekley CM, Raoul A, Alsayed A, Wu T, Lee SS, He C, Olopade OI. Inhibition of Copper Transport Induces Apoptosis in Triple-Negative Breast Cancer Cells and Suppresses Tumor Angiogenesis. Mol Cancer Ther. 2019 05; 18(5):873-885. PMID: 30824611.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    119. He C. Special Issue on Regulating the Central Dogma. Biochemistry. 2019 02 05; 58(5):295-296. PMID: 30717600.
      Citations: 2     Fields:    Translation:HumansCells
    120. He PC, He C. mRNA acetylation: a new addition to the epitranscriptome. Cell Res. 2019 02; 29(2):91-92. PMID: 30631155; PMCID: PMC6355864.
      Citations: 2     Fields:    Translation:Cells
    121. Hsu PJ, He C. High-Resolution Mapping of N 6-Methyladenosine Using m6A Crosslinking Immunoprecipitation Sequencing (m6A-CLIP-Seq). Methods Mol Biol. 2019; 1870:69-79. PMID: 30539547; PMCID: PMC6530771.
      Citations: 5     Fields:    Translation:HumansCells
    122. Wang X, Li Y, Chen W, Shi H, Eren AM, Morozov A, He C, Luo GZ, Pan T. Transcriptome-wide reprogramming of N6-methyladenosine modification by the mouse microbiome. Cell Res. 2019 02; 29(2):167-170. PMID: 30559439; PMCID: PMC6355850.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    123. Zhao BS, Roundtree IA, He C. Publisher Correction: Post-transcriptional gene regulation by mRNA modifications. Nat Rev Mol Cell Biol. 2018 Dec; 19(12):808. PMID: 30341428.
      Citations: 15     Fields:    
    124. Hsu PJ, Fei Q, Dai Q, Shi H, Dominissini D, Ma L, He C. Single base resolution mapping of 2'-O-methylation sites in human mRNA and in 3' terminal ends of small RNAs. Methods. 2019 03 01; 156:85-90. PMID: 30471344; PMCID: PMC6397781.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    125. Zhong X, Yu J, Frazier K, Weng X, Li Y, Cham CM, Dolan K, Zhu X, Hubert N, Tao Y, Lin F, Martinez-Guryn K, Huang Y, Wang T, Liu J, He C, Chang EB, Leone V. Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation. Cell Rep. 2018 11 13; 25(7):1816-1828.e4. PMID: 30428350; PMCID: PMC6532766.
      Citations: 134     Fields:    Translation:HumansAnimalsCells
    126. Shi H, Zhang X, Weng YL, Lu Z, Liu Y, Lu Z, Li J, Hao P, Zhang Y, Zhang F, Wu Y, Delgado JY, Su Y, Patel MJ, Cao X, Shen B, Huang X, Ming GL, Zhuang X, Song H, He C, Zhou T. m6A facilitates hippocampus-dependent learning and memory through YTHDF1. Nature. 2018 11; 563(7730):249-253. PMID: 30401835; PMCID: PMC6226095.
      Citations: 246     Fields:    Translation:AnimalsCells
    127. Frye M, Harada BT, Behm M, He C. RNA modifications modulate gene expression during development. Science. 2018 09 28; 361(6409):1346-1349. PMID: 30262497; PMCID: PMC6436390.
      Citations: 541     Fields:    Translation:HumansAnimalsCells
    128. Nachtergaele S, He C. Chemical Modifications in the Life of an mRNA Transcript. Annu Rev Genet. 2018 11 23; 52:349-372. PMID: 30230927; PMCID: PMC6436393.
      Citations: 91     Fields:    Translation:HumansCells
    129. Wei J, Liu F, Lu Z, Fei Q, Ai Y, He PC, Shi H, Cui X, Su R, Klungland A, Jia G, Chen J, He C. Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm. Mol Cell. 2018 09 20; 71(6):973-985.e5. PMID: 30197295; PMCID: PMC6151148.
      Citations: 368     Fields:    Translation:HumansAnimalsCells
    130. Liu J, Eckert MA, Harada BT, Liu SM, Lu Z, Yu K, Tienda SM, Chryplewicz A, Zhu AC, Yang Y, Huang JT, Chen SM, Xu ZG, Leng XH, Yu XC, Cao J, Zhang Z, Liu J, Lengyel E, He C. m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 09; 20(9):1074-1083. PMID: 30154548; PMCID: PMC6245953.
      Citations: 426     Fields:    Translation:HumansAnimalsCells
    131. Koranda JL, Dore L, Shi H, Patel MJ, Vaasjo LO, Rao MN, Chen K, Lu Z, Yi Y, Chi W, He C, Zhuang X. Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning. Neuron. 2018 07 25; 99(2):283-292.e5. PMID: 30056831; PMCID: PMC6082022.
      Citations: 79     Fields:    Translation:Animals
    132. Cheng JX, Chen L, Li Y, Cloe A, Yue M, Wei J, Watanabe KA, Shammo JM, Anastasi J, Shen QJ, Larson RA, He C, Le Beau MM, Vardiman JW. Author Correction: RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia. Nat Commun. 2018 06 06; 9(1):2286. PMID: 29875356; PMCID: PMC5989218.
      Citations: 5     Fields:    
    133. Cheng JX, Chen L, Li Y, Cloe A, Yue M, Wei J, Watanabe KA, Shammo JM, Anastasi J, Shen QJ, Larson RA, He C, Le Beau MM, Vardiman JW. RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia. Nat Commun. 2018 03 21; 9(1):1163. PMID: 29563491; PMCID: PMC5862959.
      Citations: 114     Fields:    Translation:HumansCells
    134. Wang XP, Liu YL, Mei LY, He CF, Niu ZJ, Sun J, Zhao YL, Feng Y, Zhang H. Wnt signaling pathway involvement in genotypic and phenotypic variations in Waardenburg syndrome type 2 with MITF mutations. J Hum Genet. 2018 May; 63(5):639-646. PMID: 29531335; PMCID: PMC5915419.
      Citations: 7     Fields:    Translation:HumansCells
    135. Shi H, He C. Phasing Gene Expression: mRNA N6-Methyladenosine Regulates Temporal Progression of Mammalian Cortical Neurogenesis. Biochemistry. 2018 02 20; 57(7):1055-1056. PMID: 29384655; PMCID: PMC5845840.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    136. Hsu PJ, He C. Identifying the m6A Methylome by Affinity Purification and Sequencing. Methods Mol Biol. 2018; 1649:49-57. PMID: 29130189.
      Citations: 7     Fields:    Translation:Cells
    137. Zhao BS, Nachtergaele S, Roundtree IA, He C. Our views of dynamic N6-methyladenosine RNA methylation. RNA. 2018 03; 24(3):268-272. PMID: 29222116; PMCID: PMC5824347.
      Citations: 32     Fields:    Translation:Cells
    138. Hsu PJ, He C. Making Changes: N6-Methyladenosine-Mediated Decay Drives the Endothelial-to-Hematopoietic Transition. Biochemistry. 2017 11 21; 56(46):6077-6078. PMID: 29112411; PMCID: PMC5985669.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    139. Harada BT, He C. Epigenetics: Making your mark on DNA. Nat Chem. 2017 Oct 24; 9(11):1040-1042. PMID: 29064503.
      Citations:    Fields:    Translation:HumansAnimals
    140. Hsu PJ, Shi H, He C. Epitranscriptomic influences on development and disease. Genome Biol. 2017 10 23; 18(1):197. PMID: 29061143; PMCID: PMC5654102.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    141. Roundtree IA, Luo GZ, Zhang Z, Wang X, Zhou T, Cui Y, Sha J, Huang X, Guerrero L, Xie P, He E, Shen B, He C. YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs. Elife. 2017 10 06; 6. PMID: 28984244; PMCID: PMC5648532.
      Citations: 603     Fields:    Translation:HumansCells
    142. Zhao BS, He C. "Gamete On" for m6A: YTHDF2 Exerts Essential Functions in Female Fertility. Mol Cell. 2017 Sep 21; 67(6):903-905. PMID: 28938096.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    143. Wang XP, Hao ZQ, Liu YL, Mei LY, He CF, Niu ZJ, Sun J, Zhao YL, Feng Y. Functional analysis of a SOX10 gene mutation associated with Waardenburg syndrome II. Biochem Biophys Res Commun. 2017 11 04; 493(1):258-262. PMID: 28893539.
      Citations: 3     Fields:    Translation:Humans
    144. Hsu PJ, Zhu Y, Ma H, Guo Y, Shi X, Liu Y, Qi M, Lu Z, Shi H, Wang J, Cheng Y, Luo G, Dai Q, Liu M, Guo X, Sha J, Shen B, He C. Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis. Cell Res. 2017 Sep; 27(9):1115-1127. PMID: 28809393; PMCID: PMC5587856.
      Citations: 488     Fields:    Translation:AnimalsCells
    145. Roundtree IA, Evans ME, Pan T, He C. Dynamic RNA Modifications in Gene Expression Regulation. Cell. 2017 Jun 15; 169(7):1187-1200. PMID: 28622506; PMCID: PMC5657247.
      Citations: 1462     Fields:    Translation:HumansAnimalsCells
    146. Luo GZ, He C. DNA N6-methyladenine in metazoans: functional epigenetic mark or bystander? Nat Struct Mol Biol. 2017 Jun 06; 24(6):503-506. PMID: 28586322.
      Citations: 32     Fields:    Translation:Animals
    147. Dai Q, Moshitch-Moshkovitz S, Han D, Kol N, Amariglio N, Rechavi G, Dominissini D, He C. Nm-seq maps 2'-O-methylation sites in human mRNA with base precision. Nat Methods. 2017 Jul; 14(7):695-698. PMID: 28504680; PMCID: PMC5712428.
      Citations: 146     Fields:    Translation:HumansCells
    148. Karpus J, Bosscher M, Ajiboye I, Zhang L, He C. Chromate Binding and Removal by the Molybdate-Binding Protein ModA. Chembiochem. 2017 04 04; 18(7):633-637. PMID: 28150901.
      Citations: 4     Fields:    Translation:Cells
    149. Zhao BS, Wang X, Beadell AV, Lu Z, Shi H, Kuuspalu A, Ho RK, He C. m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition. Nature. 2017 02 23; 542(7642):475-478. PMID: 28192787; PMCID: PMC5323276.
      Citations: 267     Fields:    Translation:AnimalsCells
    150. Shi H, Wang X, Lu Z, Zhao BS, Ma H, Hsu PJ, Liu C, He C. YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA. Cell Res. 2017 Mar; 27(3):315-328. PMID: 28106072; PMCID: PMC5339834.
      Citations: 894     Fields:    Translation:HumansCells
    151. Ma L, Zhao B, Chen K, Thomas A, Tuteja JH, He X, He C, White KP. Evolution of transcript modification by N6-methyladenosine in primates. Genome Res. 2017 03; 27(3):385-392. PMID: 28052920; PMCID: PMC5340966.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    152. Weekley CM, He C. Developing drugs targeting transition metal homeostasis. Curr Opin Chem Biol. 2017 Apr; 37:26-32. PMID: 28040658; PMCID: PMC5947866.
      Citations: 31     Fields:    Translation:HumansAnimals
    153. Li Z, Weng H, Su R, Weng X, Zuo Z, Li C, Huang H, Nachtergaele S, Dong L, Hu C, Qin X, Tang L, Wang Y, Hong GM, Huang H, Wang X, Chen P, Gurbuxani S, Arnovitz S, Li Y, Li S, Strong J, Neilly MB, Larson RA, Jiang X, Zhang P, Jin J, He C, Chen J. FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase. Cancer Cell. 2017 01 09; 31(1):127-141. PMID: 28017614; PMCID: PMC5234852.
      Citations: 760     Fields:    Translation:HumansCells
    154. Nachtergaele S, He C. The emerging biology of RNA post-transcriptional modifications. RNA Biol. 2017 02; 14(2):156-163. PMID: 27937535; PMCID: PMC5324755.
      Citations: 107     Fields:    Translation:HumansAnimalsCells
    155. Zhao BS, Roundtree IA, He C. Post-transcriptional gene regulation by mRNA modifications. Nat Rev Mol Cell Biol. 2017 01; 18(1):31-42. PMID: 27808276; PMCID: PMC5167638.
      Citations: 1069     Fields:    Translation:HumansAnimalsCells
    156. Liu F, Clark W, Luo G, Wang X, Fu Y, Wei J, Wang X, Hao Z, Dai Q, Zheng G, Ma H, Han D, Evans M, Klungland A, Pan T, He C. ALKBH1-Mediated tRNA Demethylation Regulates Translation. Cell. 2016 Oct 20; 167(3):816-828.e16. PMID: 27745969; PMCID: PMC5119773.
      Citations: 228     Fields:    Translation:HumansCells
    157. Liu J, Zhu Y, Luo GZ, Wang X, Yue Y, Wang X, Zong X, Chen K, Yin H, Fu Y, Han D, Wang Y, Chen D, He C. Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig. Nat Commun. 2016 10 07; 7:13052. PMID: 27713410; PMCID: PMC5059759.
      Citations: 97     Fields:    Translation:AnimalsCells
    158. Shi H, He C. A glance at N(6)-methyladenosine in transcript isoforms. Nat Methods. 2016 07 28; 13(8):624-5. PMID: 27467725.
      Citations:    Fields:    Translation:Humans
    159. Han D, Lu X, Shih AH, Nie J, You Q, Xu MM, Melnick AM, Levine RL, He C. A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations. Mol Cell. 2016 08 18; 63(4):711-719. PMID: 27477909; PMCID: PMC4992443.
      Citations: 85     Fields:    Translation:AnimalsCells
    160. Yang YA, Zhao JC, Fong KW, Kim J, Li S, Song C, Song B, Zheng B, He C, Yu J. FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function. Nucleic Acids Res. 2016 09 30; 44(17):8153-64. PMID: 27257062; PMCID: PMC5041455.
      Citations: 37     Fields:    Translation:HumansCells
    161. Luo GZ, Wang F, Weng X, Chen K, Hao Z, Yu M, Deng X, Liu J, He C. Characterization of eukaryotic DNA N(6)-methyladenine by a highly sensitive restriction enzyme-assisted sequencing. Nat Commun. 2016 Apr 15; 7:11301. PMID: 27079427; PMCID: PMC4835550.
      Citations: 45     Fields:    Translation:AnimalsCells
    162. Roundtree IA, He C. Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing. Trends Genet. 2016 06; 32(6):320-321. PMID: 27050931.
      Citations: 69     Fields:    Translation:AnimalsCells
    163. Ji Q, Chen PJ, Qin G, Deng X, Hao Z, Wawrzak Z, Yeo WS, Quang JW, Cho H, Luo GZ, Weng X, You Q, Luan CH, Yang X, Bae T, Yu K, Jiang H, He C. Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus. Nat Commun. 2016 Mar 18; 7:11000. PMID: 26987594; PMCID: PMC4802049.
      Citations: 17     Fields:    Translation:Cells
    164. Dominissini D, Nachtergaele S, Moshitch-Moshkovitz S, Peer E, Kol N, Ben-Haim MS, Dai Q, Di Segni A, Salmon-Divon M, Clark WC, Zheng G, Pan T, Solomon O, Eyal E, Hershkovitz V, Han D, Amariglio N, Rechavi G, He C, Doré LC. The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA. Nature. 2016 Feb 25; 530(7591):441-6. PMID: 26863196; PMCID: PMC4842015.
      Citations: 482     Fields:    Translation:HumansAnimalsCells
    165. Chen K, Zhao BS, He C. Nucleic Acid Modifications in Regulation of Gene Expression. Cell Chem Biol. 2016 Jan 21; 23(1):74-85. PMID: 26933737; PMCID: PMC4779186.
      Citations: 105     Fields:    Translation:HumansAnimalsCells
    166. Huang H, Jiang X, Wang J, Li Y, Song CX, Chen P, Li S, Gurbuxani S, Arnovitz S, Wang Y, Weng H, Neilly MB, He C, Li Z, Chen J. Identification of MLL-fusion/MYC?miR-26?TET1 signaling circuit in MLL-rearranged leukemia. Cancer Lett. 2016 Mar 28; 372(2):157-65. PMID: 26791235; PMCID: PMC4809417.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    167. Dai Q, Sanstead PJ, Peng CS, Han D, He C, Tokmakoff A. Weakened N3 Hydrogen Bonding by 5-Formylcytosine and 5-Carboxylcytosine Reduces Their Base-Pairing Stability. ACS Chem Biol. 2016 Feb 19; 11(2):470-7. PMID: 26641274; PMCID: PMC4782585.
      Citations: 26     Fields:    Translation:Cells
    168. Roundtree IA, He C. RNA epigenetics--chemical messages for posttranscriptional gene regulation. Curr Opin Chem Biol. 2016 Feb; 30:46-51. PMID: 26625014; PMCID: PMC4731286.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    169. Hu L, He C. Detecting hepatocellular carcinoma in blood. Cell Res. 2015 Dec; 25(12):1279-80. PMID: 26596784; PMCID: PMC4670993.
      Citations:    Fields:    Translation:HumansCells
    170. Wang J, Luo C, Shan C, You Q, Lu J, Elf S, Zhou Y, Wen Y, Vinkenborg JL, Fan J, Kang H, Lin R, Han D, Xie Y, Karpus J, Chen S, Ouyang S, Luan C, Zhang N, Ding H, Merkx M, Liu H, Chen J, Jiang H, He C. Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation. Nat Chem. 2015 Dec; 7(12):968-79. PMID: 26587712; PMCID: PMC4725056.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    171. Luo GZ, Blanco MA, Greer EL, He C, Shi Y. DNA N(6)-methyladenine: a new epigenetic mark in eukaryotes? Nat Rev Mol Cell Biol. 2015 Dec; 16(12):705-10. PMID: 26507168; PMCID: PMC4763336.
      Citations: 88     Fields:    Translation:AnimalsCells
    172. He C. Chemical decaging in living systems. Natl Sci Rev. 2015 Sep; 2(3):250-251. PMID: 26413369; PMCID: PMC4581529.
      Citations: 1     
    173. Zheng G, Qin Y, Clark WC, Dai Q, Yi C, He C, Lambowitz AM, Pan T. Efficient and quantitative high-throughput tRNA sequencing. Nat Methods. 2015 Sep; 12(9):835-837. PMID: 26214130; PMCID: PMC4624326.
      Citations: 289     Fields:    Translation:HumansCells
    174. Chen K, Luo GZ, He C. High-Resolution Mapping of N6-Methyladenosine in Transcriptome and Genome Using a Photo-Crosslinking-Assisted Strategy. Methods Enzymol. 2015; 560:161-85. PMID: 26253971.
      Citations: 22     Fields:    Translation:HumansCells
    175. Yu M, Ji L, Neumann DA, Chung DH, Groom J, Westpheling J, He C, Schmitz RJ. Base-resolution detection of N4-methylcytosine in genomic DNA using 4mC-Tet-assisted-bisulfite- sequencing. Nucleic Acids Res. 2015 Dec 02; 43(21):e148. PMID: 26184871; PMCID: PMC4666385.
      Citations: 32     Fields:    Translation:AnimalsCells
    176. Yue Y, Liu J, He C. RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation. Genes Dev. 2015 Jul 01; 29(13):1343-55. PMID: 26159994; PMCID: PMC4511210.
      Citations: 470     Fields:    Translation:HumansAnimalsCells
    177. He C. Decoding the transcriptome and DNA methylome of human primordial germ cells. Sci China Life Sci. 2015 Jul; 58(7):729-30. PMID: 26059858.
      Citations:    Fields:    Translation:HumansCells
    178. Wang X, Zhao BS, Roundtree IA, Lu Z, Han D, Ma H, Weng X, Chen K, Shi H, He C. N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency. Cell. 2015 Jun 04; 161(6):1388-99. PMID: 26046440; PMCID: PMC4825696.
      Citations: 1665     Fields:    Translation:HumansCells
    179. Cheglakov Z, Cronin TM, He C, Weizmann Y. Live Cell MicroRNA Imaging Using Cascade Hybridization Reaction. J Am Chem Soc. 2015 May 20; 137(19):6116-9. PMID: 25932784.
      Citations: 32     Fields:    Translation:HumansCells
    180. Fu Y, Luo GZ, Chen K, Deng X, Yu M, Han D, Hao Z, Liu J, Lu X, Dore LC, Weng X, Ji Q, Mets L, He C. N6-methyldeoxyadenosine marks active transcription start sites in Chlamydomonas. Cell. 2015 May 07; 161(4):879-892. PMID: 25936837; PMCID: PMC4427561.
      Citations: 220     Fields:    Translation:AnimalsCells
    181. Liu J, Yue Y, He C. Preparation of Human Nuclear RNA m6A Methyltransferases and Demethylases and Biochemical Characterization of Their Catalytic Activity. Methods Enzymol. 2015; 560:117-30. PMID: 26253968; PMCID: PMC5971108.
      Citations: 3     Fields:    Translation:HumansCells
    182. He C, Cole P. Introduction: epigenetics. Chem Rev. 2015 Mar 25; 115(6):2223-4. PMID: 25804907; PMCID: PMC4729185.
      Citations: 2     Fields:    Translation:HumansAnimals
    183. Liu N, Dai Q, Zheng G, He C, Parisien M, Pan T. N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions. Nature. 2015 Feb 26; 518(7540):560-4. PMID: 25719671; PMCID: PMC4355918.
      Citations: 1042     Fields:    Translation:HumansCells
    184. Lu X, Zhao BS, He C. TET family proteins: oxidation activity, interacting molecules, and functions in diseases. Chem Rev. 2015 Mar 25; 115(6):2225-39. PMID: 25675246; PMCID: PMC4784441.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    185. Lu X, Han D, Zhao BS, Song CX, Zhang LS, He C, Doré LC. Base-resolution maps of 5-formylcytosine and 5-carboxylcytosine reveal genome-wide DNA demethylation dynamics. Cell Res. 2015 Mar; 25(3):386-9. PMID: 25591929; PMCID: PMC4349244.
      Citations: 35     Fields:    Translation:AnimalsCells
    186. Chen X, Velmurugu Y, Zheng G, Park B, Shim Y, Kim Y, Liu L, Van Houten B, He C, Ansari A, Min JH. Kinetic gating mechanism of DNA damage recognition by Rad4/XPC. Nat Commun. 2015 Jan 06; 6:5849. PMID: 25562780; PMCID: PMC4354021.
      Citations: 48     Fields:    Translation:AnimalsCells
    187. Chen K, Lu Z, Wang X, Fu Y, Luo GZ, Liu N, Han D, Dominissini D, Dai Q, Pan T, He C. High-resolution N(6) -methyladenosine (m(6) A) map using photo-crosslinking-assisted m(6) A sequencing. Angew Chem Int Ed Engl. 2015 Jan 26; 54(5):1587-90. PMID: 25491922; PMCID: PMC4396828.
      Citations: 202     Fields:    Translation:HumansCells
    188. He C. Visualizing a protein's sugars. Natl Sci Rev. 2014 Dec; 1(4):480-481. PMID: 26114009; PMCID: PMC4477842.
      Citations:    
    189. Luo GZ, MacQueen A, Zheng G, Duan H, Dore LC, Lu Z, Liu J, Chen K, Jia G, Bergelson J, He C. Unique features of the m6A methylome in Arabidopsis thaliana. Nat Commun. 2014 Nov 28; 5:5630. PMID: 25430002; PMCID: PMC4248235.
      Citations: 217     Fields:    Translation:Animals
    190. Yu M, Song CX, He C. Detection of mismatched 5-hydroxymethyluracil in DNA by selective chemical labeling. Methods. 2015 Jan 15; 72:16-20. PMID: 25462560; PMCID: PMC4300242.
      Citations: 7     Fields:    Translation:AnimalsCells
    191. Zhao BS, He C. Pseudouridine in a new era of RNA modifications. Cell Res. 2015 Feb; 25(2):153-4. PMID: 25367125; PMCID: PMC4650566.
      Citations: 45     Fields:    Translation:HumansAnimals
    192. Wang X, He C. Dynamic RNA modifications in posttranscriptional regulation. Mol Cell. 2014 Oct 02; 56(1):5-12. PMID: 25280100; PMCID: PMC7129666.
      Citations: 77     Fields:    Translation:Cells
    193. Deng X, Liang H, Chen K, He C, Lan L, Tang X. Molecular mechanisms of two-component system RhpRS regulating type III secretion system in Pseudomonas syringae. Nucleic Acids Res. 2014 Oct; 42(18):11472-86. PMID: 25249629; PMCID: PMC4191427.
      Citations: 19     Fields:    Translation:Cells
    194. Cheng Y, Dai Q, Morshed RA, Fan X, Wegscheid ML, Wainwright DA, Han Y, Zhang L, Auffinger B, Tobias AL, Thaci B, Ahmed AU, Warnke PC, He C, Lesniak MS, Rincón E. Blood-brain barrier permeable gold nanoparticles: an efficient delivery platform for enhanced malignant glioma therapy and imaging. Small. 2014 Dec 29; 10(24):5137-50. PMID: 25104165; PMCID: PMC4268041.
      Citations: 70     Fields:    Translation:Animals
    195. Zheng G, Cox T, Tribbey L, Wang GZ, Iacoban P, Booher ME, Gabriel GJ, Zhou L, Bae N, Rowles J, He C, Olsen MJ. Synthesis of a FTO inhibitor with anticonvulsant activity. ACS Chem Neurosci. 2014 Aug 20; 5(8):658-65. PMID: 24834807; PMCID: PMC4140589.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    196. Deng X, Liang H, Ulanovskaya OA, Ji Q, Zhou T, Sun F, Lu Z, Hutchison AL, Lan L, Wu M, Cravatt BF, He C. Steady-state hydrogen peroxide induces glycolysis in Staphylococcus aureus and Pseudomonas aeruginosa. J Bacteriol. 2014 Jul; 196(14):2499-513. PMID: 24769698; PMCID: PMC4097596.
      Citations: 21     Fields:    Translation:Cells
    197. Wang X, He C. Reading RNA methylation codes through methyl-specific binding proteins. RNA Biol. 2014; 11(6):669-72. PMID: 24823649; PMCID: PMC4156498.
      Citations: 70     Fields:    Translation:HumansCells
    198. Dominissini D, He C. Cancer: Damage prevention targeted. Nature. 2014 Apr 10; 508(7495):191-2. PMID: 24695227.
      Citations: 7     Fields:    Translation:HumansAnimals
    199. Zhang L, Chen W, Iyer LM, Hu J, Wang G, Fu Y, Yu M, Dai Q, Aravind L, He C. A TET homologue protein from Coprinopsis cinerea (CcTET) that biochemically converts 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxylcytosine. J Am Chem Soc. 2014 Apr 02; 136(13):4801-4. PMID: 24655109; PMCID: PMC3985729.
      Citations: 23     Fields:    Translation:Animals
    200. Fu Y, Dominissini D, Rechavi G, He C. Gene expression regulation mediated through reversible m6A RNA methylation. Nat Rev Genet. 2014 May; 15(5):293-306. PMID: 24662220.
      Citations: 896     Fields:    Translation:HumansAnimalsCells
    201. Poor CB, Wegner SV, Li H, Dlouhy AC, Schuermann JP, Sanishvili R, Hinshaw JR, Riggs-Gelasco PJ, Outten CE, He C. Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2. Proc Natl Acad Sci U S A. 2014 Mar 18; 111(11):4043-8. PMID: 24591629; PMCID: PMC3964038.
      Citations: 57     Fields:    Translation:AnimalsCells
    202. Zheng G, Fu Y, He C. Nucleic acid oxidation in DNA damage repair and epigenetics. Chem Rev. 2014 Apr 23; 114(8):4602-20. PMID: 24580634; PMCID: PMC4002134.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    203. Chen W, Zhang L, Zheng G, Fu Y, Ji Q, Liu F, Chen H, He C. Crystal structure of the RNA demethylase ALKBH5 from zebrafish. FEBS Lett. 2014 Mar 18; 588(6):892-8. PMID: 24561204; PMCID: PMC3982313.
      Citations: 25     Fields:    Translation:AnimalsCells
    204. Zhou L, Bosscher M, Zhang C, Zhang L, Zhang W, Li CJ, Liu J, Jensen MP, Lai L, He C, Ozçubukçu S. A protein engineered to bind uranyl selectively and with femtomolar affinity. Nat Chem. 2014 Mar; 6(3):236-41. PMID: 24557139.
      Citations: 43     Fields:    Translation:Cells
    205. Wang HH, Chen HS, Li HB, Zhang H, Mei LY, He CF, Wang XW, Men MC, Jiang L, Liao XB, Wu H, Feng Y. Identification and functional analysis of a novel mutation in the SOX10 gene associated with Waardenburg syndrome type IV. Gene. 2014 Mar 15; 538(1):36-41. PMID: 24440785.
      Citations: 7     Fields:    Translation:HumansCells
    206. Madzo J, Liu H, Rodriguez A, Vasanthakumar A, Sundaravel S, Caces DBD, Looney TJ, Zhang L, Lepore JB, Macrae T, Duszynski R, Shih AH, Song CX, Yu M, Yu Y, Grossman R, Raumann B, Verma A, He C, Levine RL, Lavelle D, Lahn BT, Wickrema A, Godley LA. Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis. Cell Rep. 2014 Jan 16; 6(1):231-244. PMID: 24373966; PMCID: PMC3976649.
      Citations: 65     Fields:    Translation:HumansCells
    207. Liu J, Yue Y, Han D, Wang X, Fu Y, Zhang L, Jia G, Yu M, Lu Z, Deng X, Dai Q, Chen W, He C. A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation. Nat Chem Biol. 2014 Feb; 10(2):93-5. PMID: 24316715; PMCID: PMC3911877.
      Citations: 1610     Fields:    Translation:HumansAnimalsCells
    208. Wang X, Lu Z, Gomez A, Hon GC, Yue Y, Han D, Fu Y, Parisien M, Dai Q, Jia G, Ren B, Pan T, He C. N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 02; 505(7481):117-20. PMID: 24284625; PMCID: PMC3877715.
      Citations: 2069     Fields:    Translation:HumansCells
    209. Song CX, He C. Potential functional roles of DNA demethylation intermediates. Trends Biochem Sci. 2013 Oct; 38(10):480-4. PMID: 23932479; PMCID: PMC4013277.
      Citations: 67     Fields:    Translation:Cells
    210. Ji Q, Zhao BS, He C. A highly sensitive and genetically encoded fluorescent reporter for ratiometric monitoring of quinones in living cells. Chem Commun (Camb). 2013 Sep 21; 49(73):8027-9. PMID: 23903292; PMCID: PMC4007278.
      Citations: 2     Fields:    Translation:HumansCells
    211. Huang H, Jiang X, Li Z, Li Y, Song CX, He C, Sun M, Chen P, Gurbuxani S, Wang J, Hong GM, Elkahloun AG, Arnovitz S, Wang J, Szulwach K, Lin L, Street C, Wunderlich M, Dawlaty M, Neilly MB, Jaenisch R, Yang FC, Mulloy JC, Jin P, Liu PP, Rowley JD, Xu M, He C, Chen J. TET1 plays an essential oncogenic role in MLL-rearranged leukemia. Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29):11994-9. PMID: 23818607; PMCID: PMC3718141.
      Citations: 122     Fields:    Translation:HumansCells
    212. Lu X, He C. Nonenzymatic labeling of 5-hydroxymethylcytosine in nanopore sequencing. Chembiochem. 2013 Jul 22; 14(11):1289-90. PMID: 23780928.
      Citations: 2     Fields:    Translation:Cells
    213. Lu X, Song CX, Szulwach K, Wang Z, Weidenbacher P, Jin P, He C. Chemical modification-assisted bisulfite sequencing (CAB-Seq) for 5-carboxylcytosine detection in DNA. J Am Chem Soc. 2013 Jun 26; 135(25):9315-7. PMID: 23758547; PMCID: PMC3727251.
      Citations: 40     Fields:    Translation:Cells
    214. Sun M, Song CX, Huang H, Frankenberger CA, Sankarasharma D, Gomes S, Chen P, Chen J, Chada KK, He C, Rosner MR. HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):9920-5. PMID: 23716660; PMCID: PMC3683728.
      Citations: 153     Fields:    Translation:HumansAnimalsCells
    215. Song CX, Szulwach KE, Dai Q, Fu Y, Mao SQ, Lin L, Street C, Li Y, Poidevin M, Wu H, Gao J, Liu P, Li L, Xu GL, Jin P, He C. Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming. Cell. 2013 Apr 25; 153(3):678-91. PMID: 23602153; PMCID: PMC3657391.
      Citations: 259     Fields:    Translation:AnimalsCells
    216. Zheng G, Dahl JA, Niu Y, Fu Y, Klungland A, Yang YG, He C. Sprouts of RNA epigenetics: the discovery of mammalian RNA demethylases. RNA Biol. 2013 Jun; 10(6):915-8. PMID: 23619745; PMCID: PMC3904589.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    217. Deng X, Weerapana E, Ulanovskaya O, Sun F, Liang H, Ji Q, Ye Y, Fu Y, Zhou L, Li J, Zhang H, Wang C, Alvarez S, Hicks LM, Lan L, Wu M, Cravatt BF, He C. Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria. Cell Host Microbe. 2013 Mar 13; 13(3):358-70. PMID: 23498960; PMCID: PMC3652280.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    218. Ji Q, Zhang L, Jones MB, Sun F, Deng X, Liang H, Cho H, Brugarolas P, Gao YN, Peterson SN, Lan L, Bae T, He C. Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR. Proc Natl Acad Sci U S A. 2013 Mar 26; 110(13):5010-5. PMID: 23479646; PMCID: PMC3612684.
      Citations: 19     Fields:    Translation:HumansCells
    219. Liang H, Deng X, Bosscher M, Ji Q, Jensen MP, He C. Engineering bacterial two-component system PmrA/PmrB to sense lanthanide ions. J Am Chem Soc. 2013 Feb 13; 135(6):2037-9. PMID: 23350529.
      Citations: 9     Fields:    Translation:Cells
    220. Zhang L, Szulwach KE, Hon GC, Song CX, Park B, Yu M, Lu X, Dai Q, Wang X, Street CR, Tan H, Min JH, Ren B, Jin P, He C. Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing. Nat Commun. 2013; 4:1517. PMID: 23443545; PMCID: PMC3679896.
      Citations: 21     Fields:    Translation:AnimalsCells
    221. Fu Y, Jia G, Pang X, Wang RN, Wang X, Li CJ, Smemo S, Dai Q, Bailey KA, Nobrega MA, Han KL, Cui Q, He C. FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA. Nat Commun. 2013; 4:1798. PMID: 23653210; PMCID: PMC3658177.
      Citations: 202     Fields:    Translation:HumansAnimalsCells
    222. Jia G, Fu Y, He C. Reversible RNA adenosine methylation in biological regulation. Trends Genet. 2013 Feb; 29(2):108-15. PMID: 23218460; PMCID: PMC3558665.
      Citations: 198     Fields:    Translation:HumansCells
    223. Yu M, Hon GC, Szulwach KE, Song CX, Jin P, Ren B, He C. Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine. Nat Protoc. 2012 Dec; 7(12):2159-70. PMID: 23196972; PMCID: PMC3641661.
      Citations: 105     Fields:    Translation:Animals
    224. Zheng G, Dahl JA, Niu Y, Fedorcsak P, Huang CM, Li CJ, Shi Y, Wang WL, Song SH, Lu Z, Bosmans RP, Dai Q, Hao YJ, Yang X, Zhao WM, Tong WM, Wang XJ, Bogdan F, Furu K, Fu Y, Jia G, Zhao X, Liu J, Krokan HE, Klungland A, Yang YG, He C, Vågbø CB. ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Mol Cell. 2013 Jan 10; 49(1):18-29. PMID: 23177736; PMCID: PMC3646334.
      Citations: 1698     Fields:    Translation:HumansAnimalsCells
    225. Song CX, Yi C, He C. Mapping recently identified nucleotide variants in the genome and transcriptome. Nat Biotechnol. 2012 Nov; 30(11):1107-16. PMID: 23138310; PMCID: PMC3537840.
      Citations: 98     Fields:    Translation:HumansAnimalsCells
    226. Fu Y, He C. Nucleic acid modifications with epigenetic significance. Curr Opin Chem Biol. 2012 Dec; 16(5-6):516-24. PMID: 23092881; PMCID: PMC3518615.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    227. Jiang X, Huang H, Li Z, Li Y, Wang X, Gurbuxani S, Chen P, He C, You D, Zhang S, Wang J, Arnovitz S, Elkahloun A, Price C, Hong GM, Ren H, Kunjamma RB, Neilly MB, Matthews JM, Xu M, Larson RA, Le Beau MM, Slany RK, Liu PP, Lu J, Zhang J, He C, Chen J. Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia. Cancer Cell. 2012 Oct 16; 22(4):524-35. PMID: 23079661; PMCID: PMC3480215.
      Citations: 112     Fields:    Translation:HumansAnimalsCells
    228. Brugarolas P, Movahedzadeh F, Wang Y, Zhang N, Bartek IL, Gao YN, Voskuil MI, Franzblau SG, He C. The oxidation-sensing regulator (MosR) is a new redox-dependent transcription factor in Mycobacterium tuberculosis. J Biol Chem. 2012 Nov 02; 287(45):37703-12. PMID: 22992749; PMCID: PMC3488046.
      Citations: 29     Fields:    Translation:Cells
    229. Wang J, Karpus J, Zhao BS, Luo Z, Chen PR, He C. A selective fluorescent probe for carbon monoxide imaging in living cells. Angew Chem Int Ed Engl. 2012 Sep 17; 51(38):9652-6. PMID: 22930547.
      Citations: 22     Fields:    Translation:HumansCells
    230. Sun F, Ding Y, Ji Q, Liang Z, Deng X, Wong CC, Yi C, Zhang L, Xie S, Alvarez S, Hicks LM, Luo C, Jiang H, Lan L, He C. Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance. Proc Natl Acad Sci U S A. 2012 Sep 18; 109(38):15461-6. PMID: 22927394; PMCID: PMC3458358.
      Citations: 72     Fields:    Translation:AnimalsCells
    231. Hendrickx AP, Poor CB, Jureller JE, Budzik JM, He C, Schneewind O. Isopeptide bonds of the major pilin protein BcpA influence pilus structure and bundle formation on the surface of Bacillus cereus. Mol Microbiol. 2012 Jul; 85(1):152-63. PMID: 22624947; PMCID: PMC3538817.
      Citations: 6     Fields:    Translation:Cells
    232. Yu M, Hon GC, Szulwach KE, Song CX, Zhang L, Kim A, Li X, Dai Q, Shen Y, Park B, Min JH, Jin P, Ren B, He C. Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell. 2012 Jun 08; 149(6):1368-80. PMID: 22608086; PMCID: PMC3589129.
      Citations: 533     Fields:    Translation:HumansAnimalsCells
    233. Sun F, Liang H, Kong X, Xie S, Cho H, Deng X, Ji Q, Zhang H, Alvarez S, Hicks LM, Bae T, Luo C, Jiang H, He C. Quorum-sensing agr mediates bacterial oxidation response via an intramolecular disulfide redox switch in the response regulator AgrA. Proc Natl Acad Sci U S A. 2012 Jun 05; 109(23):9095-100. PMID: 22586129; PMCID: PMC3384213.
      Citations: 65     Fields:    Translation:Cells
    234. Ji Q, Zhang L, Sun F, Deng X, Liang H, Bae T, He C. Staphylococcus aureus CymR is a new thiol-based oxidation-sensing regulator of stress resistance and oxidative response. J Biol Chem. 2012 Jun 15; 287(25):21102-9. PMID: 22553203; PMCID: PMC3375533.
      Citations: 22     Fields:    Translation:HumansCells
    235. Dai Q, Lu X, Zhang L, He C. Synthesis of DNA oligos containing 2'-deoxy-2'-fluoro-D-arabinofuranosyl-5-carboxylcytosine as hTDG inhibitor. Tetrahedron. 2012 Jul 01; 68(26):5145-5151. PMID: 22711938; PMCID: PMC3375917.
      Citations: 6     Fields:    
    236. Liang H, Deng X, Ji Q, Sun F, Shen T, He C. The Pseudomonas aeruginosa global regulator VqsR directly inhibits QscR to control quorum-sensing and virulence gene expression. J Bacteriol. 2012 Jun; 194(12):3098-108. PMID: 22505688; PMCID: PMC3370851.
      Citations: 22     Fields:    Translation:Cells
    237. Zhang L, Lu X, Lu J, Liang H, Dai Q, Xu GL, Luo C, Jiang H, He C. Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat Chem Biol. 2012 Feb 12; 8(4):328-30. PMID: 22327402; PMCID: PMC3307914.
      Citations: 176     Fields:    Translation:HumansCells
    238. Deng X, Sun F, Ji Q, Liang H, Missiakas D, Lan L, He C. Expression of multidrug resistance efflux pump gene norA is iron responsive in Staphylococcus aureus. J Bacteriol. 2012 Apr; 194(7):1753-62. PMID: 22267518; PMCID: PMC3302473.
      Citations: 41     Fields:    Translation:Cells
    239. Sun F, Ji Q, Jones MB, Deng X, Liang H, Frank B, Telser J, Peterson SN, Bae T, He C. AirSR, a [2Fe-2S] cluster-containing two-component system, mediates global oxygen sensing and redox signaling in Staphylococcus aureus. J Am Chem Soc. 2012 Jan 11; 134(1):305-14. PMID: 22122613; PMCID: PMC3257388.
      Citations: 50     Fields:    Translation:Cells
    240. Dai Q, He C. Preparation of DNA containing 5-hydroxymethyl-2'-deoxycytidine modification through phosphoramidites with TBDMS as 5-hydroxymethyl protecting group. Curr Protoc Nucleic Acid Chem. 2011 Dec; Chapter 4:Unit 4.47.1-18. PMID: 22147420; PMCID: PMC3666178.
      Citations: 2     Fields:    Translation:Cells
    241. Song CX, Clark TA, Lu XY, Kislyuk A, Dai Q, Turner SW, He C, Korlach J. Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine. Nat Methods. 2011 Nov 20; 9(1):75-7. PMID: 22101853; PMCID: PMC3646335.
      Citations: 98     Fields:    Translation:Cells
    242. Jia G, Fu Y, Zhao X, Dai Q, Zheng G, Yang Y, Yi C, Lindahl T, Pan T, Yang YG, He C. N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol. 2011 Oct 16; 7(12):885-7. PMID: 22002720; PMCID: PMC3218240.
      Citations: 1917     Fields:    Translation:HumansCells
    243. Capretto DA, Brouwer C, Poor CB, He C. Gold(I)-catalyzed formation of 3-pyrazolines through cycloaddition of diaziridine to alkynes. Org Lett. 2011 Nov 04; 13(21):5842-5. PMID: 21988670.
      Citations: 3     Fields:    Translation:Cells
    244. Qian Y, Karpus J, Kabil O, Zhang SY, Zhu HL, Banerjee R, Zhao J, He C. Selective fluorescent probes for live-cell monitoring of sulphide. Nat Commun. 2011 Oct 11; 2:495. PMID: 21988911.
      Citations: 82     Fields:    Translation:HumansCells
    245. Sun F, Zhou L, Zhao BC, Deng X, Cho H, Yi C, Jian X, Song CX, Luan CH, Bae T, Li Z, He C. Targeting MgrA-mediated virulence regulation in Staphylococcus aureus. Chem Biol. 2011 Aug 26; 18(8):1032-41. PMID: 21867918; PMCID: PMC3163066.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    246. Aryal BP, Brugarolas P, He C. Binding of ReO4(-) with an engineered MoO4(2-)-binding protein: towards a new approach in radiopharmaceutical applications. J Biol Inorg Chem. 2012 Jan; 17(1):97-106. PMID: 21861186.
      Citations: 5     Fields:    Translation:Cells
    247. Mandal K, Wegner S, Jensen MP, He C, Özçubukçu S. Selective recognition of americium by peptide-based reagents. Inorg Chem. 2011 Sep 05; 50(17):7937-9. PMID: 21819087.
      Citations: 2     Fields:    Translation:Cells
    248. Brugarolas P, Duguid EM, Zhang W, Poor CB, He C. Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus. Acta Crystallogr D Biol Crystallogr. 2011 Aug; 67(Pt 8):707-15. PMID: 21795812; PMCID: PMC3144853.
      Citations: 4     Fields:    Translation:HumansCells
    249. Dai Q, He C. Syntheses of 5-formyl- and 5-carboxyl-dC containing DNA oligos as potential oxidation products of 5-hydroxymethylcytosine in DNA. Org Lett. 2011 Jul 01; 13(13):3446-9. PMID: 21648398; PMCID: PMC3150843.
      Citations: 17     Fields:    Translation:Cells
    250. Song CX, Sun Y, Dai Q, Lu XY, Yu M, Yang CG, He C. Detection of 5-hydroxymethylcytosine in DNA by transferring a keto-glucose by using T4 phage ß-glucosyltransferase. Chembiochem. 2011 Jul 25; 12(11):1682-5. PMID: 21656634; PMCID: PMC4065167.
      Citations: 12     Fields:    Translation:HumansCells
    251. Dolan KT, Duguid EM, He C. Crystal structures of SlyA protein, a master virulence regulator of Salmonella, in free and DNA-bound states. J Biol Chem. 2011 Jun 24; 286(25):22178-85. PMID: 21550983; PMCID: PMC3121362.
      Citations: 48     Fields:    Translation:Cells
    252. Song CX, He C. Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes. Acc Chem Res. 2011 Sep 20; 44(9):709-17. PMID: 21539303; PMCID: PMC3646476.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    253. Dai Q, Song CX, Pan T, He C. Syntheses of two 5-hydroxymethyl-2'-deoxycytidine phosphoramidites with TBDMS as the 5-hydroxymethyl protecting group and their incorporation into DNA. J Org Chem. 2011 May 20; 76(10):4182-8. PMID: 21462947; PMCID: PMC4031239.
      Citations: 10     Fields:    
    254. Song CX, Yu M, Dai Q, He C. Detection of 5-hydroxymethylcytosine in a combined glycosylation restriction analysis (CGRA) using restriction enzyme Taq(a)I. Bioorg Med Chem Lett. 2011 Sep 01; 21(17):5075-7. PMID: 21524909; PMCID: PMC3156281.
      Citations: 10     Fields:    Translation:Cells
    255. Sun F, Cho H, Jeong DW, Li C, He C, Bae T. Aureusimines in Staphylococcus aureus are not involved in virulence. PLoS One. 2010 Dec 29; 5(12):e15703. PMID: 21209955; PMCID: PMC3012096.
      Citations: 30     Fields:    Translation:Cells
    256. Wegner SV, Sun F, Hernandez N, He C. The tightly regulated copper window in yeast. Chem Commun (Camb). 2011 Mar 07; 47(9):2571-3. PMID: 21180717.
      Citations: 30     Fields:    Translation:AnimalsCells
    257. Song CX, Szulwach KE, Fu Y, Dai Q, Yi C, Li X, Li Y, Chen CH, Zhang W, Jian X, Wang J, Zhang L, Looney TJ, Zhang B, Godley LA, Hicks LM, Lahn BT, Jin P, He C. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol. 2011 Jan; 29(1):68-72. PMID: 21151123; PMCID: PMC3107705.
      Citations: 525     Fields:    Translation:HumansAnimalsCells
    258. He C. Grand challenge commentary: RNA epigenetics? Nat Chem Biol. 2010 Dec; 6(12):863-5. PMID: 21079590.
      Citations: 226     Fields:    Translation:HumansAnimalsCells
    259. Fu Y, Dai Q, Zhang W, Ren J, Pan T, He C. The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA. Angew Chem Int Ed Engl. 2010 Nov 15; 49(47):8885-8. PMID: 20583019; PMCID: PMC3134247.
      Citations: 80     Fields:    Translation:HumansCells
    260. Yi C, Jia G, Hou G, Dai Q, Zhang W, Zheng G, Jian X, Yang CG, Cui Q, He C. Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase. Nature. 2010 Nov 11; 468(7321):330-3. PMID: 21068844; PMCID: PMC3058853.
      Citations: 67     Fields:    Translation:HumansCells
    261. Saikia M, Fu Y, Pavon-Eternod M, He C, Pan T. Genome-wide analysis of N1-methyl-adenosine modification in human tRNAs. RNA. 2010 Jul; 16(7):1317-27. PMID: 20484468; PMCID: PMC2885681.
      Citations: 74     Fields:    Translation:HumansCells
    262. Lan L, Cheng A, Dunman PM, Missiakas D, He C. Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureus. J Bacteriol. 2010 Jun; 192(12):3068-77. PMID: 20400547; PMCID: PMC2901709.
      Citations: 70     Fields:    Translation:AnimalsCells
    263. Lu L, Yi C, Jian X, Zheng G, He C. Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system. Nucleic Acids Res. 2010 Jul; 38(13):4415-25. PMID: 20223766; PMCID: PMC2910035.
      Citations: 28     Fields:    Translation:Cells
    264. Wegner SV, Arslan H, Sunbul M, Yin J, He C. Dynamic copper(I) imaging in mammalian cells with a genetically encoded fluorescent copper(I) sensor. J Am Chem Soc. 2010 Mar 03; 132(8):2567-9. PMID: 20131768.
      Citations: 43     Fields:    Translation:AnimalsCells
    265. Sun F, Li C, Jeong D, Sohn C, He C, Bae T. In the Staphylococcus aureus two-component system sae, the response regulator SaeR binds to a direct repeat sequence and DNA binding requires phosphorylation by the sensor kinase SaeS. J Bacteriol. 2010 Apr; 192(8):2111-27. PMID: 20172998; PMCID: PMC2849438.
      Citations: 71     Fields:    Translation:Cells
    266. Lan L, Murray TS, Kazmierczak BI, He C. Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection. Mol Microbiol. 2010 Jan; 75(1):76-91. PMID: 19943895; PMCID: PMC2881571.
      Citations: 41     Fields:    Translation:AnimalsCells
    267. Budzik JM, Poor CB, Faull KF, Whitelegge JP, He C, Schneewind O. Intramolecular amide bonds stabilize pili on the surface of bacilli. Proc Natl Acad Sci U S A. 2009 Nov 24; 106(47):19992-7. PMID: 19903875; PMCID: PMC2785280.
      Citations: 38     Fields:    Translation:Cells
    268. Jian X, Wasinger EC, Lockard JV, Chen LX, He C. Highly sensitive and selective gold(I) recognition by a metalloregulator in Ralstonia metallidurans. J Am Chem Soc. 2009 Aug 12; 131(31):10869-71. PMID: 19606897.
      Citations: 13     Fields:    Translation:Cells
    269. Poor CB, Chen PR, Duguid E, Rice PA, He C. Crystal structures of the reduced, sulfenic acid, and mixed disulfide forms of SarZ, a redox active global regulator in Staphylococcus aureus. J Biol Chem. 2009 Aug 28; 284(35):23517-24. PMID: 19586910; PMCID: PMC2749125.
      Citations: 46     Fields:    Translation:Cells
    270. Yi C, Yang CG, He C. A non-heme iron-mediated chemical demethylation in DNA and RNA. Acc Chem Res. 2009 Apr 21; 42(4):519-29. PMID: 19852088; PMCID: PMC2920458.
      Citations: 44     Fields:    Translation:HumansCells
    271. Lin Y, Zhao T, Jian X, Farooqui Z, Qu X, He C, Dinner AR, Scherer NF. Using the bias from flow to elucidate single DNA repair protein sliding and interactions with DNA. Biophys J. 2009 Mar 04; 96(5):1911-7. PMID: 19254550; PMCID: PMC2717288.
      Citations: 11     Fields:    Translation:Cells
    272. Wegner SV, Boyaci H, Chen H, Jensen MP, He C. Engineering a uranyl-specific binding protein from NikR. Angew Chem Int Ed Engl. 2009; 48(13):2339-41. PMID: 19199314.
      Citations: 16     Fields:    
    273. He C. Chemical methods to study protein-nucleic acid interactions. Nucleic Acids Symp Ser (Oxf). 2009; (53):43. PMID: 19749251.
      Citations:    Fields:    Translation:Cells
    274. Yang S, Li Z, Jian X, He C. Platinum(II)-catalyzed intramolecular cyclization of o-substituted aryl alkynes through sp3 C-H activation. Angew Chem Int Ed Engl. 2009; 48(22):3999-4001. PMID: 19402084.
      Citations: 4     Fields:    Translation:Cells
    275. Shigdel UK, He C. A new 1'-methylenedisulfide deoxyribose that forms an efficient cross-link to DNA cytosine-5 methyltransferase (DNMT). J Am Chem Soc. 2008 Dec 31; 130(52):17634-5. PMID: 19108695.
      Citations: 3     Fields:    Translation:Cells
    276. Richter S, Anderson VJ, Garufi G, Lu L, Budzik JM, Joachimiak A, He C, Schneewind O, Missiakas D. Capsule anchoring in Bacillus anthracis occurs by a transpeptidation reaction that is inhibited by capsidin. Mol Microbiol. 2009 Jan; 71(2):404-20. PMID: 19017271; PMCID: PMC2770442.
      Citations: 34     Fields:    Translation:AnimalsCells
    277. Chen PR, Nishida S, Poor CB, Cheng A, Bae T, Kuechenmeister L, Dunman PM, Missiakas D, He C. A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus. Mol Microbiol. 2009 Jan; 71(1):198-211. PMID: 19007410; PMCID: PMC2698432.
      Citations: 66     Fields:    Translation:AnimalsCells
    278. Qiu Z, Lu L, Jian X, He C. A diazirine-based nucleoside analogue for efficient DNA interstrand photocross-linking. J Am Chem Soc. 2008 Nov 05; 130(44):14398-9. PMID: 18842048; PMCID: PMC2945524.
      Citations: 13     Fields:    Translation:Cells
    279. Jia G, Yang CG, Yang S, Jian X, Yi C, Zhou Z, He C. Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. FEBS Lett. 2008 Oct 15; 582(23-24):3313-9. PMID: 18775698; PMCID: PMC2577709.
      Citations: 186     Fields:    Translation:HumansAnimalsCells
    280. Chen H, Hu J, Chen PR, Lan L, Li Z, Hicks LM, Dinner AR, He C. The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism. Proc Natl Acad Sci U S A. 2008 Sep 09; 105(36):13586-91. PMID: 18757728; PMCID: PMC2533233.
      Citations: 68     Fields:    Translation:Cells
    281. Li Z, Brouwer C, He C. Gold-catalyzed organic transformations. Chem Rev. 2008 Aug; 108(8):3239-65. PMID: 18613729.
      Citations: 162     Fields:    Translation:Cells
    282. Yang CG, Yi C, Duguid EM, Sullivan CT, Jian X, Rice PA, He C. Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature. 2008 Apr 24; 452(7190):961-5. PMID: 18432238; PMCID: PMC2587245.
      Citations: 130     Fields:    Translation:HumansCells
    283. Chen PR, He C. Selective recognition of metal ions by metalloregulatory proteins. Curr Opin Chem Biol. 2008 Apr; 12(2):214-21. PMID: 18258210.
      Citations: 32     Fields:    Translation:Cells
    284. Shigdel UK, Zhang J, He C. Diazirine-based DNA photo-cross-linking probes for the study of protein-DNA interactions. Angew Chem Int Ed Engl. 2008; 47(1):90-3. PMID: 17994596.
      Citations: 20     Fields:    Translation:HumansCells
    285. Durek T, Zhang J, He C, Kent SB. Synthesis of photoactive analogues of a cystine knot trypsin inhibitor protein. Org Lett. 2007 Dec 20; 9(26):5497-500. PMID: 18041846.
      Citations: 1     Fields:    Translation:Cells
    286. Chen PR, Wasinger EC, Zhao J, van der Lelie D, Chen LX, He C. Spectroscopic insights into lead(II) coordination by the selective lead(II)-binding protein PbrR691. J Am Chem Soc. 2007 Oct 17; 129(41):12350-1. PMID: 17880216.
      Citations: 11     Fields:    Translation:Cells
    287. Li Z, Capretto DA, Rahaman RO, He C. Gold(III)-catalyzed nitrene insertion into aromatic and benzylic C-H groups. J Am Chem Soc. 2007 Oct 10; 129(40):12058-9. PMID: 17880068.
      Citations: 17     Fields:    
    288. Wegner SV, Okesli A, Chen P, He C. Design of an emission ratiometric biosensor from MerR family proteins: a sensitive and selective sensor for Hg2+. J Am Chem Soc. 2007 Mar 28; 129(12):3474-5. PMID: 17335208.
      Citations: 24     Fields:    Translation:Cells
    289. Li Z, Capretto DA, Rahaman R, He C. Silver-catalyzed intermolecular amination of C--H groups. Angew Chem Int Ed Engl. 2007; 46(27):5184-6. PMID: 17535005.
      Citations: 31     Fields:    Translation:Cells
    290. Chen PR, Bae T, Williams WA, Duguid EM, Rice PA, Schneewind O, He C. An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus. Nat Chem Biol. 2006 Nov; 2(11):591-5. PMID: 16980961.
      Citations: 107     Fields:    Translation:Cells
    291. Li Z, Zhang J, Brouwer C, Yang CG, Reich NW, He C. Brønsted acid catalyzed addition of phenols, carboxylic acids, and tosylamides to simple olefins. Org Lett. 2006 Sep 14; 8(19):4175-8. PMID: 16956180.
      Citations: 36     Fields:    
    292. Li Z, Ding X, He C. Nitrene transfer reactions catalyzed by gold complexes. J Org Chem. 2006 Aug 04; 71(16):5876-80. PMID: 16872166.
      Citations: 15     Fields:    
    293. Brouwer C, He C. Efficient gold-catalyzed hydroamination of 1,3-dienes. Angew Chem Int Ed Engl. 2006 Mar 03; 45(11):1744-7. PMID: 16453358.
      Citations: 15     Fields:    
    294. Zhang J, Yang CG, He C. Gold(I)-catalyzed intra- and intermolecular hydroamination of unactivated olefins. J Am Chem Soc. 2006 Feb 15; 128(6):1798-9. PMID: 16464072.
      Citations: 31     Fields:    
    295. Mishina Y, He C. Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins. J Inorg Biochem. 2006 Apr; 100(4):670-8. PMID: 16469386; PMCID: PMC2386269.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    296. Mishina Y, Duguid EM, He C. Direct reversal of DNA alkylation damage. Chem Rev. 2006 Feb; 106(2):215-32. PMID: 16464003; PMCID: PMC2432087.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    297. Mishina Y, Yang CG, He C. Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins. J Am Chem Soc. 2005 Oct 26; 127(42):14594-5. PMID: 16231911; PMCID: PMC2432083.
      Citations: 46     Fields:    Translation:HumansCells
    298. Yang CG, Reich NW, Shi Z, He C. Intramolecular additions of alcohols and carboxylic acids to inert olefins catalyzed by silver(I) triflate. Org Lett. 2005 Oct 13; 7(21):4553-6. PMID: 16209477.
      Citations: 15     Fields:    
    299. Duguid EM, Rice PA, He C. The structure of the human AGT protein bound to DNA and its implications for damage detection. J Mol Biol. 2005 Jul 22; 350(4):657-66. PMID: 15964013.
      Citations: 49     Fields:    Translation:HumansCells
    300. Yang CG, He C. Gold(I)-catalyzed intermolecular addition of phenols and carboxylic acids to olefins. J Am Chem Soc. 2005 May 18; 127(19):6966-7. PMID: 15884936.
      Citations: 18     Fields:    
    301. Chen P, Greenberg B, Taghavi S, Romano C, van der Lelie D, He C. An exceptionally selective lead(II)-regulatory protein from Ralstonia metallidurans: development of a fluorescent lead(II) probe. Angew Chem Int Ed Engl. 2005 Apr 29; 44(18):2715-2719. PMID: 15800869.
      Citations: 22     Fields:    Translation:Cells
    302. Mishina Y, Chen LX, He C. Preparation and characterization of the native iron(II)-containing DNA repair AlkB protein directly from Escherichia coli. J Am Chem Soc. 2004 Dec 29; 126(51):16930-6. PMID: 15612731.
      Citations: 22     Fields:    Translation:Cells
    303. Shi Z, He C. Direct functionalization of arenes by primary alcohol sulfonate esters catalyzed by gold(III). J Am Chem Soc. 2004 Oct 27; 126(42):13596-7. PMID: 15493899.
      Citations: 7     Fields:    
    304. Cui Y, He C. A silver-catalyzed intramolecular amidation of saturated C--h bonds. Angew Chem Int Ed Engl. 2004 Aug 13; 43(32):4210-2. PMID: 15307089.
      Citations: 30     Fields:    
    305. Shi Z, He C. Efficient functionalization of aromatic C-H bonds catalyzed by gold(III) under mild and solvent-free conditions. J Org Chem. 2004 May 28; 69(11):3669-71. PMID: 15152995.
      Citations: 22     Fields:    
    306. Shi Z, He C. An Au-catalyzed cyclialkylation of electron-rich arenes with epoxides to prepare 3-chromanols. J Am Chem Soc. 2004 May 19; 126(19):5964-5. PMID: 15137751.
      Citations: 12     Fields:    Translation:Cells
    307. He C, Mishina Y. Modeling non-heme iron proteins. Curr Opin Chem Biol. 2004 Apr; 8(2):201-8. PMID: 15062782.
      Citations: 2     Fields:    Translation:Cells
    308. Mishina Y, Lee CH, He C. Interaction of human and bacterial AlkB proteins with DNA as probed through chemical cross-linking studies. Nucleic Acids Res. 2004; 32(4):1548-54. PMID: 15004242; PMCID: PMC390304.
      Citations: 13     Fields:    Translation:Cells
    309. Chen P, He C. A general strategy to convert the MerR family proteins into highly sensitive and selective fluorescent biosensors for metal ions. J Am Chem Soc. 2004 Jan 28; 126(3):728-9. PMID: 14733542.
      Citations: 33     Fields:    Translation:Cells
    310. Cui Y, He C. Efficient aziridination of olefins catalyzed by a unique disilver(I) compound. J Am Chem Soc. 2003 Dec 31; 125(52):16202-3. PMID: 14692757.
      Citations: 18     Fields:    
    311. Duguid EM, Mishina Y, He C. How do DNA repair proteins locate potential base lesions? a chemical crosslinking method to investigate O6-alkylguanine-DNA alkyltransferases. Chem Biol. 2003 Sep; 10(9):827-35. PMID: 14522053.
      Citations: 7     Fields:    Translation:HumansCells
    312. Mishina Y, He C. Probing the structure and function of the Escherichia coli DNA alkylation repair AlkB protein through chemical cross-linking. J Am Chem Soc. 2003 Jul 23; 125(29):8730-1. PMID: 12862460.
      Citations: 13     Fields:    Translation:Cells
    He's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (844)
    Explore
    _
    Co-Authors (72)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _