 DNA, Satellite
"DNA, Satellite" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly repetitive DNA sequences found in HETEROCHROMATIN, mainly near centromeres. They are composed of simple sequences (very short) (see MINISATELLITE REPEATS) repeated in tandem many times to form large blocks of sequence. Additionally, following the accumulation of mutations, these blocks of repeats have been repeated in tandem themselves. The degree of repetition is on the order of 1000 to 10 million at each locus. Loci are few, usually one or two per chromosome. They were called satellites since in density gradients, they often sediment as distinct, satellite bands separate from the bulk of genomic DNA owing to a distinct BASE COMPOSITION.
| Descriptor ID |
D004276
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| MeSH Number(s) |
D13.444.308.480 G02.111.570.080.708.800.150 G05.360.080.708.800.150 G05.360.340.024.220.150 G05.360.340.024.850.150
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| Concept/Terms |
DNA, Satellite- DNA, Satellite
- Satellite DNA
- DNAs, Satellite
- Satellite DNAs
Satellite I DNA- Satellite I DNA
- DNA, Satellite I
- DNAs, Satellite I
- I DNA, Satellite
- I DNAs, Satellite
- Satellite I DNAs
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Below are MeSH descriptors whose meaning is more general than "DNA, Satellite".
- Chemicals and Drugs [D]
- Nucleic Acids, Nucleotides, and Nucleosides [D13]
- Nucleic Acids [D13.444]
- DNA [D13.444.308]
- DNA, Satellite [D13.444.308.480]
- Biological Sciences [G]
- Chemical Phenomena [G02]
- Biochemical Phenomena [G02.111]
- Molecular Structure [G02.111.570]
- Base Sequence [G02.111.570.080]
- Repetitive Sequences, Nucleic Acid [G02.111.570.080.708]
- Tandem Repeat Sequences [G02.111.570.080.708.800]
- DNA, Satellite [G02.111.570.080.708.800.150]
- Genetic Phenomena [G05]
- Genetic Structures [G05.360]
- Base Sequence [G05.360.080]
- Repetitive Sequences, Nucleic Acid [G05.360.080.708]
- Tandem Repeat Sequences [G05.360.080.708.800]
- DNA, Satellite [G05.360.080.708.800.150]
- Genome [G05.360.340]
- Genome Components [G05.360.340.024]
- DNA, Intergenic [G05.360.340.024.220]
- DNA, Satellite [G05.360.340.024.220.150]
- Tandem Repeat Sequences [G05.360.340.024.850]
- DNA, Satellite [G05.360.340.024.850.150]
Below are MeSH descriptors whose meaning is more specific than "DNA, Satellite".
This graph shows the total number of publications written about "DNA, Satellite" by people in this website by year, and whether "DNA, Satellite" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 3 | 1 | 4 | | 1993 | 3 | 1 | 4 | | 1995 | 2 | 3 | 5 | | 1998 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "DNA, Satellite" by people in Profiles.
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Altemose N, Miga KH, Maggioni M, Willard HF. Genomic characterization of large heterochromatic gaps in the human genome assembly. PLoS Comput Biol. 2014 May; 10(5):e1003628.
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Miga KH, Newton Y, Jain M, Altemose N, Willard HF, Kent WJ. Centromere reference models for human chromosomes X and Y satellite arrays. Genome Res. 2014 Apr; 24(4):697-707.
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Hayden KE, Strome ED, Merrett SL, Lee HR, Rudd MK, Willard HF. Sequences associated with centromere competency in the human genome. Mol Cell Biol. 2013 Feb; 33(4):763-72.
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Hayden KE, Willard HF. Composition and organization of active centromere sequences in complex genomes. BMC Genomics. 2012 Jul 20; 13:324.
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Lee HR, Hayden KE, Willard HF. Organization and molecular evolution of CENP-A--associated satellite DNA families in a basal primate genome. Genome Biol Evol. 2011; 3:1136-49.
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Basu J, Willard HF, Stromberg G. Human artificial chromosome assembly by transposon-based retrofitting of genomic BACs with synthetic alpha-satellite arrays. Curr Protoc Hum Genet. 2007 Jan; Chapter 5:Unit 5.18.
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Rudd MK, Wray GA, Willard HF. The evolutionary dynamics of alpha-satellite. Genome Res. 2006 Jan; 16(1):88-96.
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Basu J, Compitello G, Stromberg G, Willard HF, Van Bokkelen G. Efficient assembly of de novo human artificial chromosomes from large genomic loci. BMC Biotechnol. 2005 Jul 05; 5:21.
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Basu J, Stromberg G, Compitello G, Willard HF, Van Bokkelen G. Rapid creation of BAC-based human artificial chromosome vectors by transposition with synthetic alpha-satellite arrays. Nucleic Acids Res. 2005; 33(2):587-96.
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Rudd MK, Willard HF. Analysis of the centromeric regions of the human genome assembly. Trends Genet. 2004 Nov; 20(11):529-33.
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