Clustered Regularly Interspaced Short Palindromic Repeats
"Clustered Regularly Interspaced Short Palindromic Repeats" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Repetitive nucleic acid sequences that are principal components of the archaeal and bacterial CRISPR-CAS SYSTEMS, which function as adaptive antiviral defense systems.
Descriptor ID |
D064112
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MeSH Number(s) |
G02.111.570.080.708.800.325.500 G05.360.080.708.800.325.500 G05.360.340.024.850.069
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Concept/Terms |
Clustered Regularly Interspaced Short Palindromic Repeats- Clustered Regularly Interspaced Short Palindromic Repeats
- CRISPRs
- CRISPR
- CRISPR Sequences
- CRISPR Sequence
- Sequence, CRISPR
- Sequences, CRISPR
- Clustered Regularly Interspaced Short Palindromic Repeat
- CRISPR Elements
- CRISPR Element
- Element, CRISPR
- Elements, CRISPR
CRISPR Spacers- CRISPR Spacers
- CRISPR Spacer
- Spacer, CRISPR
- Spacers, CRISPR
- CRISPR Spacer Sequences
- CRISPR Spacer Sequence
- Sequence, CRISPR Spacer
- Sequences, CRISPR Spacer
- Spacer Sequence, CRISPR
- Spacer Sequences, CRISPR
CRISPR-Cas Loci- CRISPR-Cas Loci
- CRISPR Cas Loci
- CRISPR-Cas Locus
- Loci, CRISPR-Cas
- Locus, CRISPR-Cas
CRISPR Loci- CRISPR Loci
- Loci, CRISPR
- Locus, CRISPR
- CRISPR Clusters
- CRISPR Cluster
- Cluster, CRISPR
- Clusters, CRISPR
- CRISPR Locus
- CRISPR Arrays
- Array, CRISPR
- Arrays, CRISPR
- CRISPR Array
|
Below are MeSH descriptors whose meaning is more general than "Clustered Regularly Interspaced Short Palindromic Repeats".
Below are MeSH descriptors whose meaning is more specific than "Clustered Regularly Interspaced Short Palindromic Repeats".
This graph shows the total number of publications written about "Clustered Regularly Interspaced Short Palindromic Repeats" by people in this website by year, and whether "Clustered Regularly Interspaced Short Palindromic Repeats" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2016 | 1 | 1 | 2 |
2017 | 0 | 1 | 1 |
2018 | 1 | 1 | 2 |
2019 | 3 | 1 | 4 |
2020 | 1 | 2 | 3 |
2021 | 0 | 1 | 1 |
2022 | 1 | 1 | 2 |
2023 | 2 | 0 | 2 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Clustered Regularly Interspaced Short Palindromic Repeats" by people in Profiles.
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Gene regulatory network inference from CRISPR perturbations in primary CD4+ T cells elucidates the genomic basis of immune disease. Cell Genom. 2024 Nov 13; 4(11):100671.
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A new Bayesian factor analysis method improves detection of genes and biological processes affected by perturbations in single-cell CRISPR screening. Nat Methods. 2023 Nov; 20(11):1693-1703.
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First full views of a CRISPR-guided system for gene insertion. Nature. 2023 01; 613(7945):634-635.
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Whole-genome CRISPR screening identifies N-glycosylation as a genetic and therapeutic vulnerability in CALR-mutant MPNs. Blood. 2022 09 15; 140(11):1291-1304.
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Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networks. Nat Genet. 2022 08; 54(8):1133-1144.
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CRISPR screening in human hematopoietic stem and progenitor cells reveals an enrichment for tumor suppressor genes within chromosome 7 commonly deleted regions. Leukemia. 2022 05; 36(5):1421-1425.
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Accelerating functional gene discovery in osteoarthritis. Nat Commun. 2021 01 20; 12(1):467.
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The network structure and eco-evolutionary dynamics of CRISPR-induced immune diversification. Nat Ecol Evol. 2020 12; 4(12):1650-1660.
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Comment on "RNA-guided DNA insertion with CRISPR-associated transposases". Science. 2020 06 05; 368(6495).
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Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation. Nat Genet. 2020 06; 52(6):615-625.