 Gene Conversion
"Gene Conversion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The asymmetrical segregation of genes during replication which leads to the production of non-reciprocal recombinant strands and the apparent conversion of one allele into another. Thus, e.g., the meiotic products of an Aa individual may be AAAa or aaaA instead of AAaa, i.e., the A allele has been converted into the a allele or vice versa.
| Descriptor ID |
D005785
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| MeSH Number(s) |
G05.355.760.615.475
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| Concept/Terms |
Gene Conversion- Gene Conversion
- Conversion, Gene
- Conversions, Gene
- Gene Conversions
Polar Recombination- Polar Recombination
- Polar Recombinations
- Recombination, Polar
- Recombinations, Polar
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Below are MeSH descriptors whose meaning is more general than "Gene Conversion".
Below are MeSH descriptors whose meaning is more specific than "Gene Conversion".
This graph shows the total number of publications written about "Gene Conversion" by people in this website by year, and whether "Gene Conversion" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 0 | 1 | 1 | | 1993 | 0 | 1 | 1 | | 2001 | 1 | 2 | 3 | | 2002 | 1 | 1 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 2 | 2 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 2 | 0 | 2 | | 2016 | 0 | 2 | 2 | | 2017 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Conversion" by people in Profiles.
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MacQueen A, Tian D, Chang W, Holub E, Kreitman M, Bergelson J. Population Genetics of the Highly Polymorphic RPP8 Gene Family. Genes (Basel). 2019 09 08; 10(9).
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Harpak A, Lan X, Gao Z, Pritchard JK. Frequent nonallelic gene conversion on the human lineage and its effect on the divergence of gene duplicates. Proc Natl Acad Sci U S A. 2017 11 28; 114(48):12779-12784.
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Moorjani P, Gao Z, Przeworski M. Human Germline Mutation and the Erratic Evolutionary Clock. PLoS Biol. 2016 Oct; 14(10):e2000744.
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Moorjani P, Amorim CE, Arndt PF, Przeworski M. Variation in the molecular clock of primates. Proc Natl Acad Sci U S A. 2016 09 20; 113(38):10607-12.
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Tsabar M, Mason JM, Chan YL, Bishop DK, Haber JE. Caffeine inhibits gene conversion by displacing Rad51 from ssDNA. Nucleic Acids Res. 2015 Aug 18; 43(14):6902-18.
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Williams AL, Genovese G, Dyer T, Altemose N, Truax K, Jun G, Patterson N, Myers SR, Curran JE, Duggirala R, Blangero J, Reich D, Przeworski M. Non-crossover gene conversions show strong GC bias and unexpected clustering in humans. Elife. 2015 Mar 25; 4.
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Zhang C, Gschwend AR, Ouyang Y, Long M. Evolution of gene structural complexity: an alternative-splicing-based model accounts for intron-containing retrogenes. Plant Physiol. 2014 May; 165(1):412-23.
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Qing Y, Yamazoe M, Hirota K, Dejsuphong D, Sakai W, Yamamoto KN, Bishop DK, Wu X, Takeda S. The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination. PLoS Genet. 2011 Jul; 7(7):e1002148.
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Longerich S, Orelli BJ, Martin RW, Bishop DK, Storb U. Brca1 in immunoglobulin gene conversion and somatic hypermutation. DNA Repair (Amst). 2008 Feb 01; 7(2):253-66.
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Hellenthal G, Stephens M. msHOT: modifying Hudson's ms simulator to incorporate crossover and gene conversion hotspots. Bioinformatics. 2007 Feb 15; 23(4):520-1.
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