"Lactulose" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A synthetic disaccharide used in the treatment of constipation and hepatic encephalopathy. It has also been used in the diagnosis of gastrointestinal disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p887)
| Descriptor ID |
D007792
|
| MeSH Number(s) |
D09.698.629.305.423 D09.947.750.423
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lactulose".
Below are MeSH descriptors whose meaning is more specific than "Lactulose".
This graph shows the total number of publications written about "Lactulose" by people in this website by year, and whether "Lactulose" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lactulose" by people in Profiles.
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A synbiotic of Anaerostipes caccae and lactulose prevents and treats food allergy in mice. Cell Host Microbe. 2024 Jul 10; 32(7):1163-1176.e6.
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Bifidobacteria metabolize lactulose to optimize gut metabolites and prevent systemic infection in patients with liver disease. Nat Microbiol. 2023 Nov; 8(11):2033-2049.
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Ascorbic Acid may Exacerbate Aspirin-Induced Increase in Intestinal Permeability. Basic Clin Pharmacol Toxicol. 2015 Sep; 117(3):195-203.
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Differential trafficking of saccharidic probes following aspirin in clinical tests of intestinal permeability in young healthy women. Clin Exp Pharmacol Physiol. 2014 Feb; 41(2):107-17.
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The effect of aspirin and smoking on urinary excretion profiles of lactulose and mannitol in young women: toward a dynamic, aspirin augmented, test of gut mucosal permeability. Neurogastroenterol Motil. 2012 Sep; 24(9):e401-11.
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Effect of lactulose on bacterial translocation and intestinal adaptation in a rat model of short bowel syndrome. J Pediatr Gastroenterol Nutr. 2008 May; 46(5):507-13.
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The cost-effectiveness and budget impact of competing therapies in hepatic encephalopathy - a decision analysis. Aliment Pharmacol Ther. 2007 Oct 15; 26(8):1147-61.
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Short duration exercise increases breath hydrogen excretion after lactulose ingestion: description of a new phenomenon. Am J Gastroenterol. 2002 Nov; 97(11):2798-802.
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Effects of enteric-coated methylnaltrexone in preventing opioid-induced delay in oral-cecal transit time. Clin Pharmacol Ther. 2000 Apr; 67(4):398-404.
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The lactulose hydrogen breath test as a measure of orocaecal transit time. Eur J Surg. 1994 Aug; 160(8):409-16.