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Aaron Esser-Kahn

TitleProfessor
InstitutionUniversity of Chicago
DepartmentPritzker Institute for Molecular Engineering
AddressChicago IL 60637
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    U01AI182180     (DARVILLE, TONI)May 10, 2024 - Mar 31, 2029
    NIH
    Development of a recombinant protein vaccine for Chlamydia trachomatis
    Role: Co-Principal Investigator
    U01AI124286     (ESSER-KAHN, AARON P)Mar 8, 2016 - Feb 28, 2021
    NIH
    Determining the Mechanism of Activation of Linked Agonists Synergies
    Role: Principal Investigator
    R13AI118141     (ESSER-KAHN, AARON P)Mar 1, 2015 - Feb 29, 2016
    NIH
    Immuno-modulatory Approaches to Vaccine Adjuvants - An 2015 ACS Symposia
    Role: Principal Investigator
    DP2AI112194     (ESSER-KAHN, AARON PALMER)Sep 24, 2013 - Aug 31, 2018
    NIH
    Directing the Immune System via Polymeric Combinations of Molecular Signals
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zvi U, Candido DR, Weiss AM, Jones AR, Chen L, Golovina I, Yu X, Wang S, Talapin DV, Flatté ME, Esser-Kahn AP, Maurer PC. Engineering spin coherence in core-shell diamond nanocrystals. Proc Natl Acad Sci U S A. 2025 May 27; 122(21):e2422542122. PMID: 40397672.
      Citations:    Fields:    
    2. Wijfjes Z, Ramos Tomillero I, Le Gall CM, van Dinther EAW, Turlings F, Classens R, Manna S, van Dalen D, Peters RJRW, Schouren K, Fennemann FL, Hagemans IM, van Dalen FJ, van der Schoot JMS, Figdor CG, Esser-Kahn A, Scheeren FA, Verdoes M. Co-delivery of antigen and adjuvant by site-specific conjugation to dendritic cell-targeted Fab fragments potentiates T cell responses. RSC Chem Biol. 2025 May 05. PMID: 40343174; PMCID: PMC12057635.
      Citations:    
    3. Poston TB, Girardi J, Kim M, Zwarycz P, Polson AG, Yount KS, Hanlan C, Jaras Salas I, Lammert SM, Arroyo D, Bruno T, Wu M, Rozzelle J, Fairman J, Esser-Kahn AP, Darville T. Intranasal immunization with CPAF combined with ADU-S100 induces an effector CD4 T cell response and reduces bacterial burden following intravaginal infection with Chlamydia muridarum. Vaccine. 2025 Jan 01; 43(Pt 1):126526. PMID: 39536454; PMCID: PMC11817958.
      Citations: 1     Fields:    Translation:AnimalsCellsPHPublic Health
    4. Guo X, Xie M, Addhya A, Linder A, Zvi U, Wang S, Yu X, Deshmukh TD, Liu Y, Hammock IN, Li Z, DeVault CT, Butcher A, Esser-Kahn AP, Awschalom DD, Delegan N, Maurer PC, Heremans FJ, High AA. Direct-bonded diamond membranes for heterogeneous quantum and electronic technologies. Nat Commun. 2024 Oct 10; 15(1):8788. PMID: 39389960; PMCID: PMC11467219.
      Citations: 2     Fields:    
    5. Poston TB, Girardi J, Kim M, Zwarycz P, Polson AG, Yount K, Hanlan C, Salas IJ, Lammert SM, Arroyo D, Bruno T, Wu M, Rozzelle J, Fairman J, Esser-Kahn A, Darville T. Intranasal immunization with CPAF combined with cyclic-di-AMP induces a memory CD4 T cell response and reduces bacterial burden following intravaginal infection with Chlamydia muridarum. bioRxiv. 2024 Sep 24. PMID: 39386616; PMCID: PMC11463518.
      Citations:    
    6. Weiss AM, Lopez MA, Rosenberger MG, Kim JY, Shen J, Chen Q, Ung T, Ibeh UM, Knight HR, Rutledge NS, Studnitzer B, Rowan SJ, Esser-Kahn AP. Identification of CDK4/6 Inhibitors as Small Molecule NLRP3 Inflammasome Activators that Facilitate IL-1ß Secretion and T Cell Adjuvanticity. J Med Chem. 2024 Sep 12; 67(17):14974-14985. PMID: 39162654; PMCID: PMC11736968.
      Citations:    Fields:    Translation:HumansAnimalsCells
    7. Knight HR, Ketter E, Ung T, Weiss A, Ajit J, Chen Q, Shen J, Ip KM, Chiang CY, Barreiro L, Esser-Kahn A. High-throughput screen identifies non inflammatory small molecule inducers of trained immunity. Proc Natl Acad Sci U S A. 2024 Jul 16; 121(29):e2400413121. PMID: 38976741; PMCID: PMC11260140.
      Citations: 3     Fields:    Translation:Animals
    8. Mulder EJ, Moser B, Delgado J, Steinhardt R, Esser-Kahn AP. Protocol for localized macrophage stimulation with small-molecule TLR agonist via fluidic force microscopy. STAR Protoc. 2024 Mar 15; 5(1):102873. PMID: 38427566; PMCID: PMC10918328.
      Citations:    Fields:    Translation:Cells
    9. Cook AL, Dearborn MA, Anderberg TM, Vaidya K, Jureller JE, Esser-Kahn AP, Squires AH. Polymer Patterning by Laser-Induced Multipoint Initiation of Frontal Polymerization. ACS Appl Mater Interfaces. 2024 Apr 10; 16(14):17973-17980. PMID: 38418392; PMCID: PMC11009908.
      Citations:    Fields:    
    10. Cassaidy BJ, Moser BA, Solanki A, Chen Q, Shen J, Gotsis K, Lockhart Z, Rutledge N, Rosenberger MG, Dong Y, Davis D, Esser-Kahn AP. Immune Potentiation of PLGA Controlled-Release Vaccines for Improved Immunological Outcomes. ACS Omega. 2024 Mar 12; 9(10):11608-11614. PMID: 38496947; PMCID: PMC10938429.
      Citations: 1     
    11. Mulder EJ, Moser B, Delgado J, Steinhardt RC, Esser-Kahn AP. Evidence of collective influence in innate sensing using fluidic force microscopy. Front Immunol. 2024; 15:1340384. PMID: 38322261; PMCID: PMC10844469.
      Citations:    Fields:    Translation:Cells
    12. Jia S, Kim J, Esser-Kahn AP, Deak P. High-throughput screening identification of novel immunomodulatory combinations for the generation of tolerogenic dendritic cells. Front Med (Lausanne). 2023; 10:1298424. PMID: 38249971; PMCID: PMC10796829.
      Citations: 2     
    13. Ayarza J, Wang J, Kim H, Huang PR, Cassaidy B, Yan G, Liu C, Jaeger HM, Rowan SJ, Esser-Kahn AP. Bioinspired mechanical mineralization of organogels. Nat Commun. 2023 Dec 14; 14(1):8319. PMID: 38097549; PMCID: PMC10721619.
      Citations: 3     Fields:    
    14. Kim H, Esser-Kahn AP, Rowan SJ, Jaeger HM. Stress-activated friction in sheared suspensions probed with piezoelectric nanoparticles. Proc Natl Acad Sci U S A. 2023 Dec 05; 120(49):e2310088120. PMID: 38015840; PMCID: PMC10710073.
      Citations:    Fields:    
    15. Si Y, Wang Y, Tian Q, Wang Q, Pollard JM, Srivastava PK, Esser-Kahn AP, Collier JH, Sperling AI, Chong AS. Lung cDC1 and cDC2 dendritic cells priming naive CD8+ T cells in situ prior to migration to draining lymph nodes. Cell Rep. 2023 10 31; 42(10):113299. PMID: 37864794; PMCID: PMC10676754.
      Citations: 4     Fields:    Translation:AnimalsCells
    16. Tang Y, Kim JY, Ip CKM, Bahmani A, Chen Q, Rosenberger MG, Esser-Kahn AP, Ferguson AL. Data-driven discovery of innate immunomodulators via machine learning-guided high throughput screening. Chem Sci. 2023 Nov 15; 14(44):12747-12766. PMID: 38020385; PMCID: PMC10646978.
      Citations: 2     
    17. Weiss AM, Lopez MA, Rawe BW, Manna S, Chen Q, Mulder EJ, Rowan SJ, Esser-Kahn AP. Understanding How Cationic Polymers' Properties Inform Toxic or Immunogenic Responses via Parametric Analysis. Macromolecules. 2023 Sep 26; 56(18):7286-7299. PMID: 37781211; PMCID: PMC10537447.
      Citations: 4     Fields:    
    18. Ung T, Rutledge NS, Weiss AM, Esser-Kahn AP, Deak P. Cell-targeted vaccines: implications for adaptive immunity. Front Immunol. 2023; 14:1221008. PMID: 37662903; PMCID: PMC10468591.
      Citations: 3     Fields:    Translation:HumansAnimals
    19. Kim JY, Rosenberger MG, Rutledge NS, Esser-Kahn AP. Next-Generation Adjuvants: Applying Engineering Methods to Create and Evaluate Novel Immunological Responses. Pharmaceutics. 2023 Jun 08; 15(6). PMID: 37376133; PMCID: PMC10300703.
      Citations: 2     
    20. Kim JY, Rosenberger MG, Chen S, Ip CK, Bahmani A, Chen Q, Shen J, Tang Y, Wang A, Kenna E, Son M, Tay S, Ferguson AL, Esser-Kahn AP. Discovery of New States of Immunomodulation for Vaccine Adjuvants via High Throughput Screening: Expanding Innate Responses to PRRs. ACS Cent Sci. 2023 Mar 22; 9(3):427-439. PMID: 36968540; PMCID: PMC10037445.
      Citations: 8     
    21. Manna S, Maiti S, Shen J, Weiss A, Mulder E, Du W, Esser-Kahn AP. Nanovaccine that activates the NLRP3 inflammasome enhances tumor specific activation of anti-cancer immunity. Biomaterials. 2023 05; 296:122062. PMID: 36863071; PMCID: PMC10085859.
      Citations: 7     Fields:    Translation:HumansCells
    22. Weiss AM, Esser-Kahn AP. Size matters in non-canonical inflammasome activation and cell-mediated immunity. Cell Rep Med. 2023 01 17; 4(1):100904. PMID: 36652913; PMCID: PMC9873938.
      Citations:    Fields:    
    23. Deak P, Studnitzer B, Ung T, Steinhardt R, Swartz M, Esser-Kahn A. Isolating and targeting a highly active, stochastic dendritic cell subpopulation for improved immune responses. Cell Rep. 2022 11 01; 41(5):111563. PMID: 36323246; PMCID: PMC10099975.
      Citations: 2     Fields:    Translation:Cells
    24. Weiss AM, Hossainy S, Rowan SJ, Hubbell JA, Esser-Kahn AP. Immunostimulatory Polymers as Adjuvants, Immunotherapies, and Delivery Systems. Macromolecules. 2022 Aug 23; 55(16):6913-6937. PMID: 36034324; PMCID: PMC9404695.
      Citations: 16     Fields:    
    25. Kim SM, Studnitzer B, Esser-Kahn A. Heat Shock Protein 90's Mechanistic Role in Contact Hypersensitivity. J Immunol. 2022 06 15; 208(12):2622-2631. PMID: 35675957; PMCID: PMC9308677.
      Citations: 1     Fields:    Translation:HumansAnimals
    26. Hernandez-Davies JE, Dollinger EP, Pone EJ, Felgner J, Liang L, Strohmeier S, Jan S, Albin TJ, Jain A, Nakajima R, Jasinskas A, Krammer F, Esser-Kahn A, Felgner PL, Nie Q, Davies DH. Magnitude and breadth of antibody cross-reactivity induced by recombinant influenza hemagglutinin trimer vaccine is enhanced by combination adjuvants. Sci Rep. 2022 06 02; 12(1):9198. PMID: 35654904; PMCID: PMC9163070.
      Citations: 12     Fields:    Translation:HumansAnimals
    27. Deak P, Knight HR, Esser-Kahn A. Robust tolerogenic dendritic cells via push/pull pairing of toll-like-receptor agonists and immunomodulators reduces EAE. Biomaterials. 2022 07; 286:121571. PMID: 35597168; PMCID: PMC10152544.
      Citations: 4     Fields:    Translation:AnimalsCells
    28. Gao Y, Dearborn MA, Hemmer J, Wang Z, Esser-Kahn AP, Geubelle PH. Controllable Frontal Polymerization and Spontaneous Patterning Enabled by Phase-Changing Particles. Small. 2021 10; 17(42):e2102217. PMID: 34528371.
      Citations: 5     Fields:    Translation:Cells
    29. Kimani FW, Manna S, Moser B, Shen J, Nihesh N, Esser-Kahn AP. Improving the Adjuvanticity of Small Molecule Immune Potentiators Using Covalently Linked NF-?B Modulators. ACS Med Chem Lett. 2021 Sep 09; 12(9):1441-1448. PMID: 34527180; PMCID: PMC8436408.
      Citations: 1     
    30. Gao Y, Dearborn MA, Vyas S, Kumar A, Hemmer J, Wang Z, Wu Q, Alshangiti O, Moore JS, Esser-Kahn AP, Geubelle PH. Manipulating Frontal Polymerization and Instabilities with Phase-Changing Microparticles. J Phys Chem B. 2021 07 15; 125(27):7537-7545. PMID: 34228929.
      Citations: 3     Fields:    Translation:Cells
    31. Ayarza J, Wang Z, Wang J, Esser-Kahn AP. Mechanically Promoted Synthesis of Polymer Organogels via Disulfide Bond Cross-Linking. ACS Macro Lett. 2021 07 20; 10(7):799-804. PMID: 35549197.
      Citations: 3     Fields:    Translation:Cells
    32. Nihesh N, Manna S, Studnitzer B, Shen J, Esser-Kahn AP. A synthetic pathogen mimetic molecule induces a highly amplified synergistic immune response via activation of multiple signaling pathways. Chem Sci. 2021 Apr 01; 12(19):6646-6651. PMID: 34040739; PMCID: PMC8132936.
      Citations: 3     
    33. Weiss AM, Ajit J, Albin TJ, Kapoor N, Maroju S, Berges A, Pill L, Fairman J, Esser-Kahn AP. Site-specific antigen-adjuvant conjugation using cell-free protein synthesis enhances antigen presentation and CD8+ T-cell response. Sci Rep. 2021 03 18; 11(1):6267. PMID: 33737644; PMCID: PMC7973483.
      Citations: 4     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    34. Fratzke AP, Jan S, Felgner J, Liang L, Nakajima R, Jasinskas A, Manna S, Nihesh FN, Maiti S, Albin TJ, Esser-Kahn AP, Davies DH, Samuel JE, Felgner PL, Gregory AE. Subunit Vaccines Using TLR Triagonist Combination Adjuvants Provide Protection Against Coxiella burnetii While Minimizing Reactogenic Responses. Front Immunol. 2021; 12:653092. PMID: 33815413; PMCID: PMC8010241.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    35. Weiss AM, Macke N, Zhang Y, Esser-Kahn AP, Rowan SJ, Calvino C. In Vitro and in Vivo Analyses of the Effects of Source, Length, and Charge on the Cytotoxicity and Immunocompatibility of Cellulose Nanocrystals. ACS Biomater Sci Eng. 2021 04 12; 7(4):1450-1461. PMID: 33689287; PMCID: PMC9147985.
      Citations: 6     Fields:    
    36. Wang Z, Wang J, Ayarza J, Steeves T, Hu Z, Manna S, Esser-Kahn AP. Bio-inspired mechanically adaptive materials through vibration-induced crosslinking. Nat Mater. 2021 06; 20(6):869-874. PMID: 33619367.
      Citations: 19     Fields:    
    37. Steeves TM, Esser-Kahn AP. Demonstration of the photothermal catalysis of the Sabatier reaction using nickel nanoparticles and solar spectrum light. RSC Adv. 2021 Feb 17; 11(14):8394-8397. PMID: 35423330; PMCID: PMC8695177.
      Citations: 1     
    38. Kimani FW, Ajit J, Galluppi A, Manna S, Howitz WJ, Tang S, Esser-Kahn AP. Receptor-Ligand Kinetics Influence the Mechanism of Action of Covalently Linked TLR Ligands. ACS Chem Biol. 2021 02 19; 16(2):380-388. PMID: 33523635; PMCID: PMC8936418.
      Citations: 3     Fields:    Translation:AnimalsCells
    39. Manna S, Maiti S, Shen J, Du W, Esser-Kahn AP. Pathogen-like Nanoassemblies of Covalently Linked TLR Agonists Enhance CD8 and NK Cell-Mediated Antitumor Immunity. ACS Cent Sci. 2020 Nov 25; 6(11):2071-2078. PMID: 33274283; PMCID: PMC7706081.
      Citations: 8     
    40. Moser BA, Escalante-Buendia Y, Steinhardt RC, Rosenberger MG, Cassaidy BJ, Naorem N, Chon AC, Nguyen MH, Tran NT, Esser-Kahn AP. Small Molecule NF-?B Inhibitors as Immune Potentiators for Enhancement of Vaccine Adjuvants. Front Immunol. 2020; 11:511513. PMID: 33072085; PMCID: PMC7544742.
      Citations: 16     Fields:    Translation:AnimalsCells
    41. Moser BA, Steinhardt RC, Escalante-Buendia Y, Boltz DA, Barker KM, Cassaidy BJ, Rosenberger MG, Yoo S, McGonnigal BG, Esser-Kahn AP. Increased vaccine tolerability and protection via NF-?B modulation. Sci Adv. 2020 09; 6(37). PMID: 32917696; PMCID: PMC11206472.
      Citations: 22     Fields:    
    42. Maiti S, Manna S, Banahene N, Pham L, Liang Z, Wang J, Xu Y, Bettinger R, Zientko J, Esser-Kahn AP, Du W. From Glucose to Polymers: A Continuous Chemoenzymatic Process. Angew Chem Int Ed Engl. 2020 10 19; 59(43):18943-18947. PMID: 33448568.
      Citations: 1     Fields:    
    43. Ayarza J, Wang Z, Wang J, Huang CW, Esser-Kahn AP. 100th Anniversary of Macromolecular Science Viewpoint: Piezoelectrically Mediated Mechanochemical Reactions for Adaptive Materials. ACS Macro Lett. 2020 Sep 15; 9(9):1237-1248. PMID: 35638625.
      Citations: 6     Fields:    
    44. Deak P, Kimani F, Cassaidy B, Esser-Kahn A. Determining Whether Agonist Density or Agonist Number Is More Important for Immune Activation via Micoparticle Based Assay. Front Immunol. 2020; 11:642. PMID: 32328073; PMCID: PMC7161694.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    45. Gilkes AP, Albin TJ, Manna S, Supnet M, Ruiz S, Tom J, Badten AJ, Jain A, Nakajima R, Felgner J, Davies DH, Stetkevich SA, Zlotnik A, Pearlman E, Nalca A, Felgner PL, Esser-Kahn AP, Burkhardt AM. Tuning Subunit Vaccines with Novel TLR Triagonist Adjuvants to Generate Protective Immune Responses against Coxiella burnetii. J Immunol. 2020 02 01; 204(3):611-621. PMID: 31871024.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    46. Wu M, Moser BA, Steeves TM, Figueroa A, Wallace BM, Kim ST, Esser-Kahn AP, Steinhardt RC. Photon upconversion for the enhancement of microfluidic photochemical synthesis. RSC Adv. 2019 Aug 19; 9(45):26172-26175. PMID: 35531036; PMCID: PMC9070398.
      Citations: 1     
    47. Wang Z, Ayarza J, Esser-Kahn AP. Mechanically Initiated Bulk-Scale Free-Radical Polymerization. Angew Chem Int Ed Engl. 2019 Aug 26; 58(35):12023-12026. PMID: 31267620.
      Citations: 11     Fields:    
    48. Albin TJ, Tom JK, Manna S, Gilkes AP, Stetkevich SA, Katz BB, Supnet M, Felgner J, Jain A, Nakajima R, Jasinskas A, Zlotnik A, Pearlman E, Davies DH, Felgner PL, Burkhardt AM, Esser-Kahn AP. Linked Toll-Like Receptor Triagonists Stimulate Distinct, Combination-Dependent Innate Immune Responses. ACS Cent Sci. 2019 Jul 24; 5(7):1137-1145. PMID: 31403067; PMCID: PMC6661867.
      Citations: 25     
    49. Kimani F, Kim SM, Steinhardt R, Esser-Kahn AP. Correlating the structure and reactivity of a contact allergen, DNCB, and its analogs to sensitization potential. Bioorg Med Chem. 2019 07 01; 27(13):2985-2990. PMID: 31128992; PMCID: PMC8936417.
      Citations: 1     Fields:    Translation:Cells
    50. Maiti S, Manna S, Shen J, Esser-Kahn AP, Du W. Mitigation of Hydrophobicity-Induced Immunotoxicity by Sugar Poly(orthoesters). J Am Chem Soc. 2019 03 20; 141(11):4510-4514. PMID: 30768257; PMCID: PMC10627147.
      Citations: 9     Fields:    Translation:AnimalsCells
    51. Tom JK, Albin TJ, Manna S, Moser BA, Steinhardt RC, Esser-Kahn AP. Applications of Immunomodulatory Immune Synergies to Adjuvant Discovery and Vaccine Development. Trends Biotechnol. 2019 04; 37(4):373-388. PMID: 30470547.
      Citations: 49     Fields:    Translation:HumansAnimals
    52. Manna S, Howitz WJ, Oldenhuis NJ, Eldredge AC, Shen J, Nihesh FN, Lodoen MB, Guan Z, Esser-Kahn AP. Correction to "Immunomodulation of the NLRP3 Inflammasome through Structure-Based Activator Design and Functional Regulation via Lysosomal Rupture". ACS Cent Sci. 2018 11 28; 4(11):1593. PMID: 30555913; PMCID: PMC6276281.
      Citations: 1     
    53. Mohapatra H, Ayarza J, Sanders EC, Scheuermann AM, Griffin PJ, Esser-Kahn AP. Ultrasound Promoted Step-Growth Polymerization and Polymer Crosslinking Via Copper Catalyzed Azide-Alkyne "Click" Reaction. Angew Chem Int Ed Engl. 2018 Aug 27; 57(35):11208-11212. PMID: 29992680.
      Citations: 12     Fields:    
    54. Manna S, Howitz WJ, Oldenhuis NJ, Eldredge AC, Shen J, Nihesh FN, Lodoen MB, Guan Z, Esser-Kahn AP. Immunomodulation of the NLRP3 Inflammasome through Structure-Based Activator Design and Functional Regulation via Lysosomal Rupture. ACS Cent Sci. 2018 Aug 22; 4(8):982-995. PMID: 30159395; PMCID: PMC6107863.
      Citations: 22     
    55. Brubaker K, Garewal A, Steinhardt RC, Esser-Kahn AP. Bio-inspired counter-current multiplier for enrichment of solutes. Nat Commun. 2018 02 21; 9(1):736. PMID: 29467391; PMCID: PMC5821707.
      Citations: 2     Fields:    
    56. Ignacio BJ, Albin TJ, Esser-Kahn AP, Verdoes M. Toll-like Receptor Agonist Conjugation: A Chemical Perspective. Bioconjug Chem. 2018 03 21; 29(3):587-603. PMID: 29378134; PMCID: PMC10642707.
      Citations: 35     Fields:    Translation:HumansAnimals
    57. Esser-Kahn AP. Kiss-and-tell way to track cell contacts. Nature. 2018 01 25; 553(7689):414-415. PMID: 29368706.
      Citations: 1     Fields:    
    58. Esser-Kahn AP. Kiss-and-tell way to track cell contacts. Nature. 2018 Jan; 553(7689):414-415. PMID: 32094788.
      Citations: 1     Fields:    
    59. Van Herck S, Van Hoecke L, Louage B, Lybaert L, De Coen R, Kasmi S, Esser-Kahn AP, David SA, Nuhn L, Schepens B, Saelens X, De Geest BG. Transiently Thermoresponsive Acetal Polymers for Safe and Effective Administration of Amphotericin B as a Vaccine Adjuvant. Bioconjug Chem. 2018 03 21; 29(3):748-760. PMID: 29172458.
      Citations: 9     Fields:    Translation:Animals
    60. Steinhardt R, Hiew SC, Mohapatra H, Nguyen D, Oh Z, Truong R, Esser-Kahn A. Cooperative CO2 Absorption Isotherms from a Bifunctional Guanidine and Bifunctional Alcohol. ACS Cent Sci. 2017 Dec 27; 3(12):1271-1275. PMID: 29296667; PMCID: PMC5746851.
      Citations: 2     
    61. Steinhardt RC, Steeves TM, Wallace BM, Moser B, Fishman DA, Esser-Kahn AP. Photothermal Nanoparticle Initiation Enables Radical Polymerization and Yields Unique, Uniform Microfibers with Broad Spectrum Light. ACS Appl Mater Interfaces. 2017 Nov 08; 9(44):39034-39039. PMID: 29040810.
      Citations: 3     Fields:    
    62. Ryu KA, McGonnigal B, Moore T, Kargupta T, Mancini RJ, Esser-Kahn AP. Light Guided In-vivo Activation of Innate Immune Cells with Photocaged TLR 2/6 Agonist. Sci Rep. 2017 08 14; 7(1):8074. PMID: 28808328; PMCID: PMC5556111.
      Citations: 10     Fields:    Translation:AnimalsCells
    63. Lybaert L, Ryu KA, De Rycke R, Chon AC, De Wever O, Vermaelen KY, Esser-Kahn A, De Geest BG. Polyelectrolyte-Enrobed Cancer Cells in View of Personalized Immune-Therapy. Adv Sci (Weinh). 2017 06; 4(6):1700050. PMID: 28638786; PMCID: PMC5473321.
      Citations: 4     Fields:    
    64. Moser BA, Esser-Kahn AP. A Photoactivatable Innate Immune Receptor for Optogenetic Inflammation. ACS Chem Biol. 2017 02 17; 12(2):347-350. PMID: 28000442; PMCID: PMC5657437.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    65. Moser BA, Steinhardt RC, Esser-Kahn AP. Surface Coating of Nanoparticles Reduces Background Inflammatory Activity while Increasing Particle Uptake and Delivery. ACS Biomater Sci Eng. 2017 Feb 13; 3(2):206-213. PMID: 28936479; PMCID: PMC5604483.
      Citations: 6     Fields:    
    66. Esser-Kahn AP, Sottos NR, White SR, Moore JS. Correction to "Programmable Microcapsules from Self-Immolative Polymers. J Am Chem Soc. 2016 12 14; 138(49):16182. PMID: 27960329.
      Citations:    Fields:    
    67. Ryu KA, Slowinska K, Moore T, Esser-Kahn A. Immune Response Modulation of Conjugated Agonists with Changing Linker Length. ACS Chem Biol. 2016 12 16; 11(12):3347-3352. PMID: 27749034; PMCID: PMC5300779.
      Citations: 11     Fields:    Translation:AnimalsCells
    68. Nguyen D, Stolaroff J, Esser-Kahn A. Solvent Effects on the Photothermal Regeneration of CO2 in Monoethanolamine Nanofluids. ACS Appl Mater Interfaces. 2015 Nov 25; 7(46):25851-6. PMID: 26523847.
      Citations: 2     Fields:    
    69. Tom JK, Dotsey EY, Wong HY, Stutts L, Moore T, Davies DH, Felgner PL, Esser-Kahn AP. Modulation of Innate Immune Responses via Covalently Linked TLR Agonists. ACS Cent Sci. 2015 Nov 25; 1(8):439-448. PMID: 26640818; PMCID: PMC4665084.
      Citations: 32     
    70. Lynn GM, Laga R, Darrah PA, Ishizuka AS, Balaci AJ, Pechar M, Pola R, Gerner MY, Yamamoto A, Buechler CR, Quinn KM, Smelkinson MG, Vanek O, Cawood R, Hills T, Vasalatiy O, Francica JR, Stutts L, Tom JK, Ryu KA, Esser-Kahn AP, Etrych T, Fisher KD, Seymour LW, Seder RA, Dulcey AE, Kastenmüller K. In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity. Nat Biotechnol. 2015 Nov; 33(11):1201-10. PMID: 26501954; PMCID: PMC5842712.
      Citations: 161     Fields:    
    71. Stutts L, Esser-Kahn AP. A Light-Controlled TLR4 Agonist and Selectable Activation of Cell Subpopulations. Chembiochem. 2015 Aug 17; 16(12):1744-8. PMID: 26097006; PMCID: PMC4881745.
      Citations: 9     Fields:    Translation:AnimalsCells
    72. Mancini RJ, Stutts L, Moore T, Esser-Kahn AP. Controlling the origins of inflammation with a photoactive lipopeptide immunopotentiator. Angew Chem Int Ed Engl. 2015 May 11; 54(20):5962-5. PMID: 25800006; PMCID: PMC4539149.
      Citations: 14     Fields:    Translation:HumansCells
    73. Ryu KA, Stutts L, Tom JK, Mancini RJ, Esser-Kahn AP. Stimulation of innate immune cells by light-activated TLR7/8 agonists. J Am Chem Soc. 2014 Aug 06; 136(31):10823-5. PMID: 25029205; PMCID: PMC4132957.
      Citations: 21     Fields:    Translation:AnimalsCells
    74. Mancini RJ, Stutts L, Ryu KA, Tom JK, Esser-Kahn AP. Directing the immune system with chemical compounds. ACS Chem Biol. 2014 May 16; 9(5):1075-85. PMID: 24690004; PMCID: PMC5674983.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    75. Kleiman M, Ryu KA, Hiew S, Brubaker K, Mughnetsyan R, Truong R, Dolan B, Tackett E, Esser-Kahn AP, Nguyen du T. Three-dimensional conformal coatings through the entrapment of polymer membrane precursors. ACS Appl Mater Interfaces. 2014 Feb 26; 6(4):2830-5. PMID: 24437474.
      Citations: 1     Fields:    Translation:Cells
    76. Mancini RJ, Tom JK, Esser-Kahn AP. Covalently coupled immunostimulant heterodimers. Angew Chem Int Ed Engl. 2014 Jan 03; 53(1):189-92. PMID: 24259411; PMCID: PMC4049977.
      Citations: 16     Fields:    Translation:Cells
    77. Nguyen du T, Esser-Kahn AP. A microvascular system for chemical reactions using surface waste heat. Angew Chem Int Ed Engl. 2013 Dec 16; 52(51):13731-4. PMID: 24307247.
      Citations:    Fields:    
    78. Nguyen du T, Leho YT, Esser-Kahn AP. Process of making three-dimensional microstructures using vaporization of a sacrificial component. J Vis Exp. 2013 Nov 02; (81):e50459. PMID: 24300342; PMCID: PMC3969899.
      Citations: 2     Fields:    Translation:Cells
    79. Tom JK, Mancini RJ, Esser-Kahn AP. Covalent modification of cell surfaces with TLR agonists improves & directs immune stimulation. Chem Commun (Camb). 2013 Oct 25; 49(83):9618-20. PMID: 24022092; PMCID: PMC4399865.
      Citations: 9     Fields:    Translation:AnimalsCells
    80. Nguyen du T, Leho YT, Esser-Kahn AP. A three-dimensional microvascular gas exchange unit for carbon dioxide capture. Lab Chip. 2012 Apr 07; 12(7):1246-50. PMID: 22344348; PMCID: PMC10642706.
      Citations: 4     Fields:    Translation:Cells
    81. Dong H, Esser-Kahn AP, Thakre PR, Patrick JF, Sottos NR, White SR, Moore JS. Chemical treatment of poly(lactic acid) fibers to enhance the rate of thermal depolymerization. ACS Appl Mater Interfaces. 2012 Feb; 4(2):503-9. PMID: 22008224.
      Citations: 3     Fields:    Translation:Cells
    82. Esser-Kahn AP, Thakre PR, Dong H, Patrick JF, Vlasko-Vlasov VK, Sottos NR, Moore JS, White SR. Three-dimensional microvascular fiber-reinforced composites. Adv Mater. 2011 Aug 23; 23(32):3654-8. PMID: 21766345.
      Citations: 18     Fields:    Translation:Cells
    83. Witus LS, Moore T, Esser-Kahn AP, Scheck RA, Iavarone AT, Francis MB, Thuronyi BW. Identification of highly reactive sequences for PLP-mediated bioconjugation using a combinatorial peptide library. J Am Chem Soc. 2010 12 01; 132(47):16812-7. PMID: 21067189; PMCID: PMC2997844.
      Citations: 22     Fields:    
    84. Esser-Kahn AP, Trang V, Francis MB. Incorporation of antifreeze proteins into polymer coatings using site-selective bioconjugation. J Am Chem Soc. 2010 Sep 29; 132(38):13264-9. PMID: 20825180.
      Citations: 21     Fields:    
    85. Esser-Kahn AP, Sottos NR, White SR, Moore JS. Programmable microcapsules from self-immolative polymers. J Am Chem Soc. 2010 Aug 04; 132(30):10266-8. PMID: 20662509.
      Citations: 20     Fields:    
    86. Esser-Kahn AP, Iavarone AT, Francis MB. Metallothionein-cross-linked hydrogels for the selective removal of heavy metals from water. J Am Chem Soc. 2008 Nov 26; 130(47):15820-2. PMID: 18980305.
      Citations: 13     Fields:    Translation:Cells
    87. Esser-Kahn AP, Francis MB. Protein-cross-linked polymeric materials through site-selective bioconjugation. Angew Chem Int Ed Engl. 2008; 47(20):3751-4. PMID: 18399554.
      Citations: 13     Fields:    Translation:Cells
    88. Hooker JM, Esser-Kahn AP, Francis MB. Modification of aniline containing proteins using an oxidative coupling strategy. J Am Chem Soc. 2006 Dec 13; 128(49):15558-9. PMID: 17147343.
      Citations: 18     Fields:    Translation:Cells
    89. Gilmore JM, Scheck RA, Esser-Kahn AP, Joshi NS, Francis MB. N-terminal protein modification through a biomimetic transamination reaction. Angew Chem Int Ed Engl. 2006 Aug 11; 45(32):5307-11. PMID: 16847857.
      Citations: 83     Fields:    Translation:Cells
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