DNA, Circular
"DNA, Circular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any of the covalently closed DNA molecules found in bacteria, many viruses, mitochondria, plastids, and plasmids. Small, polydisperse circular DNA's have also been observed in a number of eukaryotic organisms and are suggested to have homology with chromosomal DNA and the capacity to be inserted into, and excised from, chromosomal DNA. It is a fragment of DNA formed by a process of looping out and deletion, containing a constant region of the mu heavy chain and the 3'-part of the mu switch region. Circular DNA is a normal product of rearrangement among gene segments encoding the variable regions of immunoglobulin light and heavy chains, as well as the T-cell receptor. (Riger et al., Glossary of Genetics, 5th ed & Segen, Dictionary of Modern Medicine, 1992)
Descriptor ID |
D004270
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MeSH Number(s) |
D13.444.308.283 G02.111.570.790.486.212 G05.360.580.156
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Concept/Terms |
DNA, Circular- DNA, Circular
- Circular DNAs
- DNAs, Circular
- Circular DNA
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Below are MeSH descriptors whose meaning is more general than "DNA, Circular".
Below are MeSH descriptors whose meaning is more specific than "DNA, Circular".
This graph shows the total number of publications written about "DNA, Circular" by people in this website by year, and whether "DNA, Circular" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1991 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2009 | 1 | 0 | 1 | 2016 | 1 | 0 | 1 | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA, Circular" by people in Profiles.
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Rankin CR, Lokhandwala ZA, Huang R, Pekow J, Pothoulakis C, Padua D. Linear and circular CDKN2B-AS1 expression is associated with Inflammatory Bowel Disease and participates in intestinal barrier formation. Life Sci. 2019 Aug 15; 231:116571.
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Krueger E, Shim J, Fathizadeh A, Chang AN, Subei B, Yocham KM, Davis PH, Graugnard E, Khalili-Araghi F, Bashir R, Estrada D, Fologea D. Modeling and Analysis of Intercalant Effects on Circular DNA Conformation. ACS Nano. 2016 09 27; 10(9):8910-7.
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Cortese R, Kwan A, Lalonde E, Bryzgunova O, Bondar A, Wu Y, Gordevicius J, Park M, Oh G, Kaminsky Z, Tverkuviene J, Laurinavicius A, Jankevicius F, Sendorek DH, Haider S, Wang SC, Jarmalaite S, Laktionov P, Boutros PC, Petronis A. Epigenetic markers of prostate cancer in plasma circulating DNA. Hum Mol Genet. 2012 Aug 15; 21(16):3619-31.
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Blinkova O, Victoria J, Li Y, Keele BF, Sanz C, Ndjango JB, Peeters M, Travis D, Lonsdorf EV, Wilson ML, Pusey AE, Hahn BH, Delwart EL. Novel circular DNA viruses in stool samples of wild-living chimpanzees. J Gen Virol. 2010 Jan; 91(Pt 1):74-86.
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Sheridan SD, Yu X, Roth R, Heuser JE, Sehorn MG, Sung P, Egelman EH, Bishop DK. A comparative analysis of Dmc1 and Rad51 nucleoprotein filaments. Nucleic Acids Res. 2008 Jul; 36(12):4057-66.
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Strissel PL, Espinosa R, Rowley JD, Swift H. Scaffold attachment regions in centromere-associated DNA. Chromosoma. 1996 Aug; 105(2):122-33.
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Schneider GJ, Lang JD, Haselkorn R. Promoter recognition by the RNA polymerase from vegetative cells of the cyanobacterium Anabaena 7120. Gene. 1991 Aug 30; 105(1):51-60.
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Locker J, Rabinowitz M, Getz GS. Electron microscopic and renaturation kinetic analysis of mitochondrial DNA of cytoplasmic petite mutants of Saccharomyces cerevisiae. J Mol Biol. 1974 Sep 15; 88(2):489-507.
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Faye G, Fukuhara H, Grandchamp C, Lazowska J, Michel F, Casey J, Getz GS, Locker J, Rabinowitz M, Bolotin-Fukuhara M, Coen D, Deutsch J, Dujon B, Netter P, Slonimski PP. Mitochondrial nucleic acids in the petite colonie mutants: deletions and repetition of genes. Biochimie. 1973; 55(6):779-92.
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Grdina DJ, Lohman PH, Hewitt RR. A fluorometric method for the detection of endodeoxyribonuclease on DNA-polyacrylamide gels. Anal Biochem. 1973 Jan; 51(1):255-64.
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