"RNA, Double-Stranded" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA consisting of two strands as opposed to the more prevalent single-stranded RNA. Most of the double-stranded segments are formed from transcription of DNA by intramolecular base-pairing of inverted complementary sequences separated by a single-stranded loop. Some double-stranded segments of RNA are normal in all organisms.
| Descriptor ID |
D012330
|
| MeSH Number(s) |
D13.444.735.490 G02.111.570.820.486.775 G05.360.580.775
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "RNA, Double-Stranded".
Below are MeSH descriptors whose meaning is more specific than "RNA, Double-Stranded".
This graph shows the total number of publications written about "RNA, Double-Stranded" by people in this website by year, and whether "RNA, Double-Stranded" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "RNA, Double-Stranded" by people in Profiles.
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Cancer cells restrict immunogenicity of retrotransposon expression via distinct mechanisms. Immunity. 2024 12 10; 57(12):2879-2894.e11.
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Identification of exceptionally potent adenosine deaminases RNA editors from high body temperature organisms. PLoS Genet. 2023 03; 19(3):e1010661.
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RNA editing underlies genetic risk of common inflammatory diseases. Nature. 2022 08; 608(7923):569-577.
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Intracellular RNA Sensing in Mammalian Cells: Role in Stress Response and Cancer Therapies. Int Rev Cell Mol Biol. 2019; 344:31-89.
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TRIM25 Binds RNA to Modulate Cellular Anti-viral Defense. J Mol Biol. 2018 12 07; 430(24):5280-5293.
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Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations. Nat Commun. 2017 08 16; 8(1):266.
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The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly. Mol Cell. 2014 Sep 04; 55(5):771-81.
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Mechanistic characterization of the 5'-triphosphate-dependent activation of PKR: lack of 5'-end nucleobase specificity, evidence for a distinct triphosphate binding site, and a critical role for the dsRBD. RNA. 2012 Oct; 18(10):1862-74.
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Involvement of Noxa in mediating cellular ER stress responses to lytic virus infection. Virology. 2011 Sep 01; 417(2):293-303.
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The DNA/RNA-dependent RNA polymerase QDE-1 generates aberrant RNA and dsRNA for RNAi in a process requiring replication protein A and a DNA helicase. PLoS Biol. 2010 Oct 05; 8(10).