 Enzymes
"Enzymes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Biological molecules that possess catalytic activity. They may occur naturally or be synthetically created. Enzymes are usually proteins, however CATALYTIC RNA and CATALYTIC DNA molecules have also been identified.
| Descriptor ID |
D004798
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| MeSH Number(s) |
D08.811
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Enzymes".
Below are MeSH descriptors whose meaning is more specific than "Enzymes".
This graph shows the total number of publications written about "Enzymes" by people in this website by year, and whether "Enzymes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1982 | 1 | 0 | 1 | | 1985 | 1 | 0 | 1 | | 1989 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 | | 1992 | 0 | 1 | 1 | | 1998 | 1 | 1 | 2 | | 1999 | 1 | 0 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2006 | 2 | 0 | 2 | | 2007 | 5 | 0 | 5 | | 2008 | 2 | 0 | 2 | | 2009 | 1 | 1 | 2 | | 2011 | 2 | 0 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 2 | 0 | 2 | | 2015 | 1 | 1 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 2 | 2 | 4 | | 2018 | 2 | 0 | 2 | | 2019 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Enzymes" by people in Profiles.
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Li G, Eckert MA, Chang JW, Montgomery JE, Chryplewicz A, Lengyel E, Moellering RE. Ultrasensitive, multiplexed chemoproteomic profiling with soluble activity-dependent proximity ligation. Proc Natl Acad Sci U S A. 2019 10 22; 116(43):21493-21500.
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Bevilacqua PC, Harris ME, Piccirilli JA, Gaines C, Ganguly A, Kostenbader K, Ekesan S, York DM. An Ontology for Facilitating Discussion of Catalytic Strategies of RNA-Cleaving Enzymes. ACS Chem Biol. 2019 06 21; 14(6):1068-1076.
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Lykins JD, Filippova EV, Halavaty AS, Minasov G, Zhou Y, Dubrovska I, Flores KJ, Shuvalova LA, Ruan J, El Bissati K, Dovgin S, Roberts CW, Woods S, Moulton JD, Moulton H, McPhillie MJ, Muench SP, Fishwick CWG, Sabini E, Shanmugam D, Roos DS, McLeod R, Anderson WF, Ngô HM. CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii. Front Cell Infect Microbiol. 2018; 8:352.
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Ou Y, Wilson RE, Weber SG. Methods of Measuring Enzyme Activity Ex Vivo and In Vivo. Annu Rev Anal Chem (Palo Alto Calif). 2018 06 12; 11(1):509-533.
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Siddiq MA, Hochberg GK, Thornton JW. Evolution of protein specificity: insights from ancestral protein reconstruction. Curr Opin Struct Biol. 2017 12; 47:113-122.
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Chakraborty K, Leung K, Krishnan Y. High lumenal chloride in the lysosome is critical for lysosome function. Elife. 2017 07 25; 6.
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Ou Y, Weber SG. Numerical Modeling of Electroosmotic Push-Pull Perfusion and Assessment of Its Application to Quantitative Determination of Enzymatic Activity in the Extracellular Space of Mammalian Tissue. Anal Chem. 2017 06 06; 89(11):5864-5873.
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Arriola KG, Oliveira AS, Ma ZX, Lean IJ, Giurcanu MC, Adesogan AT. A meta-analysis on the effect of dietary application of exogenous fibrolytic enzymes on the performance of dairy cows. J Dairy Sci. 2017 Jun; 100(6):4513-4527.
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Light SH, Cahoon LA, Halavaty AS, Freitag NE, Anderson WF. Structure to function of an a-glucan metabolic pathway that promotes Listeria monocytogenes pathogenesis. Nat Microbiol. 2016 Nov 07; 2:16202.
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Harris ME, Piccirilli JA, York DM. Enzyme transition states from theory and experiment. Biochim Biophys Acta. 2015 Nov; 1854(11):1727-8.
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