"Myosin Light Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The smaller subunits of MYOSINS that bind near the head groups of MYOSIN HEAVY CHAINS. The myosin light chains have a molecular weight of about 20 KDa and there are usually one essential and one regulatory pair of light chains associated with each heavy chain. Many myosin light chains that bind calcium are considered "calmodulin-like" proteins.
| Descriptor ID |
D018994
|
| MeSH Number(s) |
D05.750.078.730.475.200 D12.776.157.125.475 D12.776.210.500.600.200 D12.776.220.525.475.200
|
| Concept/Terms |
Myosin Light Chains- Myosin Light Chains
- Light Chains, Myosin
- Myosin Light Chain
- Light Chain, Myosin
|
Below are MeSH descriptors whose meaning is more general than "Myosin Light Chains".
Below are MeSH descriptors whose meaning is more specific than "Myosin Light Chains".
This graph shows the total number of publications written about "Myosin Light Chains" by people in this website by year, and whether "Myosin Light Chains" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 1 | 2 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 1 | 0 | 1 |
| 2003 | 2 | 0 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Myosin Light Chains" by people in Profiles.
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Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis. Nat Med. 2019 04; 25(4):690-700.
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Oxidized LDL signals through Rho-GTPase to induce endothelial cell stiffening and promote capillary formation. J Lipid Res. 2016 05; 57(5):791-808.
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Dual role of vinculin in barrier-disruptive and barrier-enhancing endothelial cell responses. Cell Signal. 2016 Jun; 28(6):541-51.
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A self-organized biomechanical network drives shape changes during tissue morphogenesis. Nature. 2015 Aug 20; 524(7565):351-5.
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Mechanosensitive PPAP2B Regulates Endothelial Responses to Atherorelevant Hemodynamic Forces. Circ Res. 2015 Jul 31; 117(4):e41-e53.
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Gap junction protein connexin43 exacerbates lung vascular permeability. PLoS One. 2014; 9(6):e100931.
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Control of vascular permeability by atrial natriuretic peptide via a GEF-H1-dependent mechanism. J Biol Chem. 2014 Feb 21; 289(8):5168-83.
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TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis. Gastroenterology. 2013 Aug; 145(2):407-15.
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Endothelial barrier disruption and recovery is controlled by substrate stiffness. Microvasc Res. 2013 May; 87:50-7.
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A role for VEGFR2 activation in endothelial responses caused by barrier disruptive OxPAPC concentrations. PLoS One. 2012; 7(1):e30957.