R-TPI: rolling toxicity probability interval design to shorten the duration and maintain safety of phase I trials.

R-TPI: rolling toxicity probability interval design to shorten the duration and maintain safety of phase I trials. J Biopharm Stat. 2019; 29(3):411-424.

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subject areas

Adult
Algorithms
Antineoplastic Agents
Child
Clinical Trials, Phase I as Topic
Cohort Studies
Computer Simulation
Decision Support Techniques
Dose-Response Relationship, Drug
Humans
Maximum Tolerated Dose
Models, Statistical
Probability
Research Design
Sample Size
Time Factors

authors with profiles

Yuan Ji