Dose-Response Relationship, Drug
"Dose-Response Relationship, Drug" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The relationship between the dose of an administered drug and the response of the organism to the drug.
| Descriptor ID |
D004305
|
| MeSH Number(s) |
G07.690.773.875 G07.690.936.500
|
| Concept/Terms |
Dose-Response Relationship, Drug- Dose-Response Relationship, Drug
- Dose-Response Relationships, Drug
- Drug Dose-Response Relationship
- Drug Dose-Response Relationships
- Relationship, Drug Dose-Response
- Relationships, Drug Dose-Response
- Dose Response Relationship, Drug
|
Below are MeSH descriptors whose meaning is more general than "Dose-Response Relationship, Drug".
Below are MeSH descriptors whose meaning is more specific than "Dose-Response Relationship, Drug".
This graph shows the total number of publications written about "Dose-Response Relationship, Drug" by people in this website by year, and whether "Dose-Response Relationship, Drug" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 22 | 22 |
| 1997 | 0 | 29 | 29 |
| 1998 | 0 | 32 | 32 |
| 1999 | 0 | 33 | 33 |
| 2000 | 0 | 46 | 46 |
| 2001 | 0 | 52 | 52 |
| 2002 | 0 | 68 | 68 |
| 2003 | 1 | 65 | 66 |
| 2004 | 0 | 70 | 70 |
| 2005 | 0 | 62 | 62 |
| 2006 | 0 | 62 | 62 |
| 2007 | 1 | 56 | 57 |
| 2008 | 1 | 64 | 65 |
| 2009 | 1 | 50 | 51 |
| 2010 | 0 | 58 | 58 |
| 2011 | 1 | 58 | 59 |
| 2012 | 0 | 48 | 48 |
| 2013 | 0 | 41 | 41 |
| 2014 | 0 | 52 | 52 |
| 2015 | 3 | 43 | 46 |
| 2016 | 0 | 34 | 34 |
| 2017 | 0 | 33 | 33 |
| 2018 | 0 | 38 | 38 |
| 2019 | 0 | 37 | 37 |
| 2020 | 1 | 13 | 14 |
| 2021 | 1 | 21 | 22 |
| 2022 | 0 | 5 | 5 |
| 2023 | 1 | 1 | 2 |
| 2024 | 1 | 10 | 11 |
| 2025 | 0 | 8 | 8 |
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Below are the most recent publications written about "Dose-Response Relationship, Drug" by people in Profiles.
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Pilot epinephrine dose-finding study to counter epidural-related blood pressure reduction. Reg Anesth Pain Med. 2025 11 05; 50(11):901-906.
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The generalized 3+3 (G3) design for Phase I trials: A design for clinicians. Contemp Clin Trials. 2025 Nov; 158:108077.
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Strengthening the Food and Drug Administration Office of Clinical Pharmacology's Labeling Authority. Clin Transl Sci. 2025 Sep; 18(9):e70337.
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Safety, Tolerability, and Pharmacokinetics of NRL-1049, a Rho-Associated Kinase Inhibitor, in Healthy Volunteers: A Phase 1, First-in-Human, Single-Ascending Dose, Randomized, Placebo-Controlled Trial. CNS Drugs. 2025 Sep; 39(9):865-877.
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Using Quantitative Approaches to Optimize Dosages for New Combinations and Subsequent Indications for Oncology Drugs. Clin Pharmacol Ther. 2025 Oct; 118(4):772-777.
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Impact of Batoclimab Treatment on LDL-C with and Without Coadministration of Atorvastatin: Results from a Phase I Randomized Study in Healthy Participants. Drug Saf. 2025 Sep; 48(9):993-1004.
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Across the spectrum: Acute alcohol responses in young adults with mild, moderate, and severe alcohol use disorder. Drug Alcohol Depend. 2025 06 01; 271:112629.
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Different chemical scaffolds bind to L-phe site in Mycobacterium tuberculosis Phe-tRNA synthetase. Eur J Med Chem. 2025 Apr 05; 287:117335.
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Exploring the rhodanine universe: Design and synthesis of fluorescent rhodanine-based derivatives as anti-fibrillar and anti-oligomer agents against a-synuclein and 2N4R tau. Bioorg Med Chem. 2024 Dec 15; 116:117990.
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Dose escalation of biologics in biologic-naive patients with Crohn's disease: Outcomes from the ODESSA-CD study. J Manag Care Spec Pharm. 2024 Nov; 30(11):1276-1287.