"Multigene Family" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
| Descriptor ID |
D005810
|
| MeSH Number(s) |
G05.360.340.024.340.645
|
| Concept/Terms |
Multigene Family- Multigene Family
- Families, Multigene
- Family, Multigene
- Multigene Families
Gene Clusters- Gene Clusters
- Cluster, Gene
- Clusters, Gene
- Gene Cluster
|
Below are MeSH descriptors whose meaning is more general than "Multigene Family".
Below are MeSH descriptors whose meaning is more specific than "Multigene Family".
This graph shows the total number of publications written about "Multigene Family" by people in this website by year, and whether "Multigene Family" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 3 | 6 | 9 |
| 1999 | 3 | 3 | 6 |
| 2000 | 4 | 1 | 5 |
| 2001 | 6 | 9 | 15 |
| 2002 | 1 | 10 | 11 |
| 2003 | 1 | 6 | 7 |
| 2004 | 2 | 5 | 7 |
| 2005 | 3 | 3 | 6 |
| 2006 | 4 | 7 | 11 |
| 2007 | 2 | 6 | 8 |
| 2008 | 1 | 7 | 8 |
| 2009 | 2 | 1 | 3 |
| 2010 | 2 | 7 | 9 |
| 2011 | 0 | 1 | 1 |
| 2012 | 2 | 6 | 8 |
| 2013 | 2 | 4 | 6 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 3 | 3 |
| 2017 | 0 | 2 | 2 |
| 2018 | 2 | 1 | 3 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 3 | 3 |
| 2021 | 0 | 1 | 1 |
| 2023 | 0 | 3 | 3 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 2 | 3 |
To return to the timeline,
click here.
Below are the most recent publications written about "Multigene Family" by people in Profiles.
-
Bryophytes hold a larger gene family space than vascular plants. Nat Genet. 2025 Oct; 57(10):2562-2569.
-
Genetic variation in the FMO and GSTO gene clusters impacts arsenic metabolism in humans. PLoS Genet. 2025 Sep; 21(9):e1011826.
-
Genome mining identifies a diversity of natural product biosynthetic capacity in human respiratory Corynebacterium strains. mSphere. 2025 Jun 25; 10(6):e0025825.
-
Two KaiABC systems control circadian oscillations in one cyanobacterium. Nat Commun. 2024 09 03; 15(1):7674.
-
The complete sequence of a human Y chromosome. Nature. 2023 09; 621(7978):344-354.
-
Widespread Detection of Yersiniabactin Gene Cluster and Its Encoding Integrative Conjugative Elements (ICEKp) among Nonoutbreak OXA-48-Producing Klebsiella pneumoniae Clinical Isolates from Spain and the Netherlands. Microbiol Spectr. 2023 08 17; 11(4):e0471622.
-
Valhidepsin Lipopeptides from Chromobacterium vaccinii: Structures, Biosynthesis, and Coregulation with FR900359 Production. J Nat Prod. 2023 02 24; 86(2):246-255.
-
Long-read metagenomics of soil communities reveals phylum-specific secondary metabolite dynamics. Commun Biol. 2021 11 18; 4(1):1302.
-
An antigenic diversification threshold for falciparum malaria transmission at high endemicity. PLoS Comput Biol. 2021 02; 17(2):e1008729.
-
GigC, a LysR Family Transcription Regulator, Is Required for Cysteine Metabolism and Virulence in Acinetobacter baumannii. Infect Immun. 2020 12 15; 89(1).