"Genes, RAG-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes involved in activating the enzyme VDJ recombinase. RAG-1 is located on chromosome 11 in humans (chromosome 2 in mice) and is expressed exclusively in maturing lymphocytes.
| Descriptor ID |
D016654
|
| MeSH Number(s) |
G05.360.340.024.340.400
|
| Concept/Terms |
Genes, RAG-1- Genes, RAG-1
- Genes, RAG 1
- Recombination-Activating Genes-1
- Recombination Activating Genes 1
- Recombination-Activating Gene-1
- Recombination Activating Gene 1
- RAG-1 Genes
- Gene, RAG-1
- RAG 1 Genes
- RAG-1 Gene
|
Below are MeSH descriptors whose meaning is more general than "Genes, RAG-1".
Below are MeSH descriptors whose meaning is more specific than "Genes, RAG-1".
This graph shows the total number of publications written about "Genes, RAG-1" by people in this website by year, and whether "Genes, RAG-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 |
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Genes, RAG-1" by people in Profiles.
-
ß-Catenin induces T-cell transformation by promoting genomic instability. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):391-6.
-
Interleukin-15 liver gene transfer increases the number and function of IKDCs and NK cells. Gene Ther. 2008 Apr; 15(7):473-83.
-
Homeostatic proliferation as an isolated variable reverses CD8+ T cell anergy and promotes tumor rejection. J Immunol. 2006 Oct 01; 177(7):4521-9.
-
Role of type 1 T helper cells in the resolution of acute Streptococcus pneumoniae sinusitis: a mouse model. J Infect Dis. 2005 Oct 01; 192(7):1237-44.
-
Distinct role of surface lymphotoxin expressed by B cells in the organization of secondary lymphoid tissues. Immunity. 2002 Sep; 17(3):239-50.
-
The role of recombination activating gene (RAG) reinduction in thymocyte development in vivo. J Exp Med. 2001 Aug 20; 194(4):471-80.
-
Antigen recognition and allogeneic tumor rejection in CD8+ TCR transgenic/RAG(-/-) mice. J Immunol. 1997 Nov 15; 159(10):4665-75.
-
Identification and characterization of the murine Rag1 promoter. Mol Immunol. 1997 Aug-Sep; 34(12-13):939-54.