"Gigantism" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The condition of accelerated and excessive GROWTH in children or adolescents who are exposed to excess HUMAN GROWTH HORMONE before the closure of EPIPHYSES. It is usually caused by somatotroph hyperplasia or a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. These patients are of abnormally tall stature, more than 3 standard deviations above normal mean height for age.
- Pituitary Gigantism
- Gigantism, Pituitary
Below are MeSH descriptors whose meaning is more general than "Gigantism".
Below are MeSH descriptors whose meaning is more specific than "Gigantism".
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Below are the most recent publications written about "Gigantism" by people in Profiles.
A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci. Nat Commun. 2021 09 06; 12(1):5253.
Gigantism and comparative life-history parameters of tyrannosaurid dinosaurs. Nature. 2004 Aug 12; 430(7001):772-5.
Disappearance rate of endogenous and exogenous human growth hormone in man. J Clin Endocrinol Metab. 1970 Mar; 30(3):386-92.