Leukoencephalopathy, Progressive Multifocal
"Leukoencephalopathy, Progressive Multifocal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7)
Descriptor ID |
D007968
|
MeSH Number(s) |
C02.182.525.500 C02.256.721.500 C02.290.575 C02.839.550 C10.228.140.430.520.750.500 C10.228.140.695.750 C10.228.228.245.340.500 C10.228.228.399.750.500 C10.314.450
|
Concept/Terms |
Leukoencephalopathy, Progressive Multifocal- Leukoencephalopathy, Progressive Multifocal
- Leukoencephalopathies, Progressive Multifocal
- Multifocal Leukoencephalopathies, Progressive
- Multifocal Leukoencephalopathy, Progressive
- Progressive Multifocal Leukoencephalopathies
- Progressive Multifocal Leukoencephalopathy
- JC Polyomavirus Encephalopathy
- Encephalopathies, JC Polyomavirus
- Encephalopathy, JC Polyomavirus
- Encephalitis, JC Polyomavirus
- JC Polyomavirus Encephalitis
|
Below are MeSH descriptors whose meaning is more general than "Leukoencephalopathy, Progressive Multifocal".
- Diseases [C]
- Virus Diseases [C02]
- Central Nervous System Viral Diseases [C02.182]
- Encephalitis, Viral [C02.182.525]
- Leukoencephalopathy, Progressive Multifocal [C02.182.525.500]
- DNA Virus Infections [C02.256]
- Polyomavirus Infections [C02.256.721]
- Leukoencephalopathy, Progressive Multifocal [C02.256.721.500]
- Encephalitis, Viral [C02.290]
- Leukoencephalopathy, Progressive Multifocal [C02.290.575]
- Slow Virus Diseases [C02.839]
- Leukoencephalopathy, Progressive Multifocal [C02.839.550]
- Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
- Brain Diseases [C10.228.140]
- Encephalitis [C10.228.140.430]
- Infectious Encephalitis [C10.228.140.430.520]
- Encephalitis, Viral [C10.228.140.430.520.750]
- Leukoencephalopathy, Progressive Multifocal [C10.228.140.430.520.750.500]
- Leukoencephalopathies [C10.228.140.695]
- Leukoencephalopathy, Progressive Multifocal [C10.228.140.695.750]
- Central Nervous System Infections [C10.228.228]
- Central Nervous System Viral Diseases [C10.228.228.245]
- Encephalitis, Viral [C10.228.228.245.340]
- Leukoencephalopathy, Progressive Multifocal [C10.228.228.245.340.500]
- Infectious Encephalitis [C10.228.228.399]
- Encephalitis, Viral [C10.228.228.399.750]
- Leukoencephalopathy, Progressive Multifocal [C10.228.228.399.750.500]
- Demyelinating Diseases [C10.314]
- Leukoencephalopathy, Progressive Multifocal [C10.314.450]
Below are MeSH descriptors whose meaning is more specific than "Leukoencephalopathy, Progressive Multifocal".
This graph shows the total number of publications written about "Leukoencephalopathy, Progressive Multifocal" by people in this website by year, and whether "Leukoencephalopathy, Progressive Multifocal" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 1 | 0 | 1 |
2005 | 1 | 1 | 2 |
2014 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukoencephalopathy, Progressive Multifocal" by people in Profiles.
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Late onset progressive multifocal leukoencephalopathy in Hodgkin lymphoma. J Clin Neurosci. 2017 Sep; 43:132-134.
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Reply. Clin Gastroenterol Hepatol. 2016 May; 14(5):776-7.
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Prevalence of Antibodies Against JC Virus in Patients With Refractory Crohn's Disease and Effects of Natalizumab Therapy. Clin Gastroenterol Hepatol. 2015 Nov; 13(11):1919-25.
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Comment on 'anti-adhesion therapies and the rule of 3 for rare events'. Am J Gastroenterol. 2014 Jul; 109(7):1083-4.
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Natalizumab induction and maintenance therapy for Crohn's disease. N Engl J Med. 2005 Nov 03; 353(18):1912-25.
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Overwhelming leukoencephalopathy as the only sign of neuropsychiatric lupus. J Rheumatol. 2005 Sep; 32(9):1843-5.
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Clinical and magnetic resonance imaging regression of progressive multifocal leukoencephalopathy in an AIDS patient after intensive antiretroviral therapy. J Neuroimaging. 2001 Jul; 11(3):336-9.
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Progressive multifocal leukoencephalopathy in patients with HIV infection: lack of impact of early diagnosis by stereotactic brain biopsy. J Acquir Immune Defic Syndr (1988). 1992 Oct; 5(10):1030-8.
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CNS complications of AIDS: CT and MR findings. AJR Am J Roentgenol. 1988 Sep; 151(3):449-54.
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Brain biopsy for encephalitis. Clin Neurosurg. 1986; 33:591-602.