 Haptens
"Haptens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small antigenic determinants capable of eliciting an immune response only when coupled to a carrier. Haptens bind to antibodies but by themselves cannot elicit an antibody response.
| Descriptor ID |
D006241
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| MeSH Number(s) |
D23.050.550.480
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Haptens".
Below are MeSH descriptors whose meaning is more specific than "Haptens".
This graph shows the total number of publications written about "Haptens" by people in this website by year, and whether "Haptens" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1984 | 1 | 0 | 1 | | 1988 | 1 | 1 | 2 | | 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Haptens" by people in Profiles.
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Fanning SW, Horn JR. An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop. Protein Sci. 2011 Jul; 20(7):1196-207.
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O'Brien RL, Marrack P, Storb U, Kappler JW. B cells expressing Ig transgenes respond to a T-dependent antigen only in the presence of Ia-compatible T cells. J Immunol. 1988 Nov 15; 141(10):3335-41.
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Godfrey HP, Canfield LS, Kindler HL, Angadi CV, Tomasek JJ, Goodman JW. Production of a fibronectin-associated lymphokine by cloned mouse T cells. J Immunol. 1988 Sep 01; 141(5):1508-15.
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Musch MW, Billah MM, Siegel MI. Antigen-and ionophore-stimulated synthesis of platelet-activating factor by the cloned mast cell line, MC9. Biochem Biophys Res Commun. 1987 May 14; 144(3):1243-50.
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Musch MW, Siegel MI. Antigenic stimulated release of arachidonic acid, lipoxygenase activity and histamine release in a cloned murine mast cell MC9. Biochem Biophys Res Commun. 1985 Jan 16; 126(1):517-25.
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Scott D, Nitecki DE, Kindler H, Goodman JW. Immunogenicity of biotinylated hapten-avidin complexes. Mol Immunol. 1984 Nov; 21(11):1055-60.
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Mäkela O, Kaartinen M, Karjalainen K, Morse HC, Weigert M, Potter M. A search for hapten-binding mouse plasmacytoma proteins. Eur J Immunol. 1979 Feb; 9(2):125-9.
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Barstad P, Hubert J, Hunkapiller M, Goetze A, Schilling J, Black B, Eaton B, Richards J, Weigert M, Hood L. Immunoglobulins with hapten-binding activity: structure-function correlations and genetic implications. Eur J Immunol. 1978 Jul; 8(7):497-503.
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Barstad P, Farnsworth V, Weigert M, Cohn M, Hood L. Mouse immunoglobulin heavy chains are coded by multiple germ line variable region genes. Proc Natl Acad Sci U S A. 1974 Oct; 71(10):4096-100.
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Carson D, Weigert M. Immunochemical analysis of the cross-reacting idiotypes of mouse myeloma proteins with anti-dextran activity and normal anti-dextran antibody. Proc Natl Acad Sci U S A. 1973 Jan; 70(1):235-9.
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