"Cellular Senescence" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing CELL DEATH. Senescence can be induced by DNA DAMAGE or other cellular stresses, such as OXIDATIVE STRESS.
| Descriptor ID |
D016922
|
| MeSH Number(s) |
G04.043
|
| Concept/Terms |
Cell Aging- Cell Aging
- Cellular Ageing
- Ageing, Cellular
- Aging, Cell
- Senescence, Replicative
- Cellular Aging
- Aging, Cellular
- Replicative Senescence
- Cell Ageing
- Ageing, Cell
Senescence-Associated Secretory Phenotype- Senescence-Associated Secretory Phenotype
- Phenotype, Senescence-Associated Secretory
- Secretory Phenotype, Senescence-Associated
- Senescence Associated Secretory Phenotype
|
Below are MeSH descriptors whose meaning is more general than "Cellular Senescence".
Below are MeSH descriptors whose meaning is more specific than "Cellular Senescence".
This graph shows the total number of publications written about "Cellular Senescence" by people in this website by year, and whether "Cellular Senescence" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 3 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 2 | 3 |
| 2008 | 3 | 0 | 3 |
| 2009 | 2 | 0 | 2 |
| 2010 | 0 | 4 | 4 |
| 2011 | 3 | 2 | 5 |
| 2012 | 2 | 1 | 3 |
| 2013 | 1 | 2 | 3 |
| 2014 | 1 | 7 | 8 |
| 2015 | 0 | 4 | 4 |
| 2016 | 3 | 2 | 5 |
| 2017 | 4 | 2 | 6 |
| 2018 | 2 | 2 | 4 |
| 2019 | 5 | 0 | 5 |
| 2020 | 2 | 2 | 4 |
| 2021 | 5 | 0 | 5 |
| 2022 | 0 | 3 | 3 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
| 2025 | 2 | 1 | 3 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cellular Senescence" by people in Profiles.
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Pancreatic ß-cell aging in physiology and diabetes: emerging roles of m6A mRNA methylation. J Mol Endocrinol. 2026 Jul 01; 77(1).
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Continuous antiretroviral therapy induces progressive senescence-like reprogramming of alveolar macrophages. Front Immunol. 2026; 17:1805936.
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Trichosanthes kirilowii extract alleviated liver fibrosis and acute myocardial infarction by inhibiting VCAN to restrain monocyte senescence: Insights from bioinformatic analyses and experimental validation. Phytomedicine. 2026 Apr; 153:157941.
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Immune cell single-cell RNA sequencing analyses link an age-associated T cell subset to symptomatic benign prostatic hyperplasia. Front Immunol. 2025; 16:1585446.
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Transforming malignant tumors into vulnerable phenotypes via nanoscale coordination polymer mediated cell senescence and photodynamic therapy. Biomaterials. 2025 Nov; 322:123355.
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Targeting cIAP2 in a novel senolytic strategy prevents glioblastoma recurrence after radiotherapy. EMBO Mol Med. 2025 04; 17(4):645-678.
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Therapy-Induced Cellular Senescence: Potentiating Tumor Elimination or Driving Cancer Resistance and Recurrence? Cells. 2024 07 30; 13(15).
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Transfer learning in a biomaterial fibrosis model identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and diverse pathologies. Geroscience. 2023 08; 45(4):2559-2587.
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Targeting telomerase reverse transcriptase with the covalent inhibitor NU-1 confers immunogenic radiation sensitization. Cell Chem Biol. 2022 10 20; 29(10):1517-1531.e7.
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Far-red Fluorescent Senescence-associated ß-Galactosidase Probe for Identification and Enrichment of Senescent Tumor Cells by Flow Cytometry. J Vis Exp. 2022 09 13; (187).