"Keratins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
| Descriptor ID |
D007633
|
| MeSH Number(s) |
D05.750.078.593.450 D12.776.220.475.450 D12.776.860.607
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Keratins".
Below are MeSH descriptors whose meaning is more specific than "Keratins".
This graph shows the total number of publications written about "Keratins" by people in this website by year, and whether "Keratins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 3 | 3 |
| 1996 | 1 | 1 | 2 |
| 1997 | 1 | 2 | 3 |
| 1999 | 2 | 2 | 4 |
| 2000 | 1 | 1 | 2 |
| 2001 | 1 | 1 | 2 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 4 | 4 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Keratins" by people in Profiles.
-
Development and validation of circulating tumour cell enumeration (Epic Sciences) as a prognostic biomarker in men with metastatic castration-resistant prostate cancer. Eur J Cancer. 2021 06; 150:83-94.
-
The molecular evolution of feathers with direct evidence from fossils. Proc Natl Acad Sci U S A. 2019 02 19; 116(8):3018-3023.
-
Expression of renal cell markers and detection of 3p loss links endolymphatic sac tumor to renal cell carcinoma and warrants careful evaluation to avoid diagnostic pitfalls. Acta Neuropathol Commun. 2018 10 19; 6(1):107.
-
Melanotic Translocation Renal Cell Carcinoma With a Novel ARID1B-TFE3 Gene Fusion. Am J Surg Pathol. 2017 Nov; 41(11):1576-1580.
-
The role of intermediate filaments in maintaining integrity and function of intestinal epithelial cells after massive bowel resection in a rat. Pediatr Surg Int. 2018 Feb; 34(2):217-225.
-
Integrated genomic and molecular characterization of cervical cancer. Nature. 2017 03 16; 543(7645):378-384.
-
Acquisition of Portal Venous Circulating Tumor Cells From Patients With Pancreaticobiliary Cancers by Endoscopic Ultrasound. Gastroenterology. 2015 Dec; 149(7):1794-1803.e4.
-
Crohn enteritis-associated small bowel adenocarcinomas exhibit gastric differentiation. Hum Pathol. 2014 Feb; 45(2):359-67.
-
Cellular pleomorphism in papillary tumors of the pineal region. Brain Tumor Pathol. 2013 Apr; 30(2):93-8.
-
Three differentiation states risk-stratify bladder cancer into distinct subtypes. Proc Natl Acad Sci U S A. 2012 Feb 07; 109(6):2078-83.