Methylnitronitrosoguanidine
"Methylnitronitrosoguanidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nitrosoguanidine derivative with potent mutagenic and carcinogenic properties.
| Descriptor ID |
D008769
|
| MeSH Number(s) |
D02.078.370.649.400 D02.654.567.400
|
| Concept/Terms |
Methylnitronitrosoguanidine- Methylnitronitrosoguanidine
- Nitrosonitromethylguanidine
- N-Methyl-N'-nitro-N-nitrosoguanidine
- N Methyl N' nitro N nitrosoguanidine
- Nitrosomethylnitroguanidine
- Methylnitrosonitroguanidine
- MNNG
|
Below are MeSH descriptors whose meaning is more general than "Methylnitronitrosoguanidine".
Below are MeSH descriptors whose meaning is more specific than "Methylnitronitrosoguanidine".
This graph shows the total number of publications written about "Methylnitronitrosoguanidine" by people in this website by year, and whether "Methylnitronitrosoguanidine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Methylnitronitrosoguanidine" by people in Profiles.
-
Exonuclease 1 (Exo1) is required for activating response to S(N)1 DNA methylating agents. DNA Repair (Amst). 2012 Dec 01; 11(12):951-64.
-
Vertebrate cells lacking FEN-1 endonuclease are viable but hypersensitive to methylating agents and H2O2. Nucleic Acids Res. 2002 Jul 15; 30(14):3273-7.
-
Roles of DNA fragmentation factor and poly(ADP-ribose) polymerase in an amplification phase of tumor necrosis factor-induced apoptosis. J Biol Chem. 2001 Oct 12; 276(41):38185-92.
-
Effect of O6-alkylguanine-DNA alkyltransferase on the frequency and spectrum of mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine in the HPRT gene of diploid human fibroblasts. Mutat Res. 1991 Sep-Oct; 250(1-2):397-409.
-
Use of antibodies to human O6-alkylguanine-DNA alkyltransferase to study the content of this protein in cells treated with O6-benzylguanine or N-methyl-N'-nitro-N-nitrosoguanidine. Carcinogenesis. 1991 Sep; 12(9):1679-83.
-
Positive control of a global antioxidant defense regulon activated by superoxide-generating agents in Escherichia coli. Proc Natl Acad Sci U S A. 1990 Aug; 87(16):6181-5.
-
Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents. Carcinogenesis. 1989 Sep; 10(9):1613-9.
-
Intracellular activation of cytotoxic agents: kinetic models for methylnitrosoureas and N-methyl-N'-nitro-N-nitrosoguanidine in cell culture. Chem Res Toxicol. 1989 May-Jun; 2(3):157-61.
-
Chromosomal sensitivity of lymphocytes from individuals with therapy-related acute nonlymphocytic leukemia. Mutat Res. 1989 Apr; 216(2):119-26.
-
Depletion of O6-methylguanine-DNA-methyltransferase in human fibroblasts increases the mutagenic response to N-methyl-N'-nitro-N-nitrosoguanidine. Carcinogenesis. 1985 Dec; 6(12):1823-6.