"Novobiocin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189)
- Crystallinic Acid
- Novobiocin Sodium
- Sodium, Novobiocin
- Novobiocin, Monosodium Salt
- Monosodium Salt Novobiocin
Below are MeSH descriptors whose meaning is more general than "Novobiocin".
Below are MeSH descriptors whose meaning is more specific than "Novobiocin".
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Below are the most recent publications written about "Novobiocin" by people in Profiles.
The effect of topoisomerase inhibitors on the expression of differentiation markers and cell cycle progression in human K-562 leukemia cells. Exp Cell Res. 1992 Nov; 203(1):100-6.
Anaerobic regulation of nitrogen-fixation genes in Rhodopseudomonas capsulata. Proc Natl Acad Sci U S A. 1986 Sep; 83(18):6805-9.