"Pyridoxal Phosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
| Descriptor ID |
D011732
|
| MeSH Number(s) |
D03.383.725.676.925.500.500 D08.211.740
|
| Concept/Terms |
Pyridoxal Phosphate- Pyridoxal Phosphate
- Phosphate, Pyridoxal
- Pyridoxal-P
- Pyridoxal P
- Pyridoxal 5-Phosphate
- Pyridoxal 5 Phosphate
|
Below are MeSH descriptors whose meaning is more general than "Pyridoxal Phosphate".
Below are MeSH descriptors whose meaning is more specific than "Pyridoxal Phosphate".
This graph shows the total number of publications written about "Pyridoxal Phosphate" by people in this website by year, and whether "Pyridoxal Phosphate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2000 | 3 | 0 | 3 |
| 2002 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pyridoxal Phosphate" by people in Profiles.
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Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB. Protein Sci. 2021 09; 30(9):1904-1918.
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Pyridoxal 5?-phosphate-responsive epilepsy with novel mutations in the PNPO gene: a case report. Genet Mol Res. 2015 Oct 30; 14(4):14130-5.
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A nutritional conditional lethal mutant due to pyridoxine 5'-phosphate oxidase deficiency in Drosophila melanogaster. G3 (Bethesda). 2014 Apr 16; 4(6):1147-54.
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Identification of highly reactive sequences for PLP-mediated bioconjugation using a combinatorial peptide library. J Am Chem Soc. 2010 12 01; 132(47):16812-7.
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Improved outcomes in islet isolation and transplantation by the use of a novel hemoglobin-based O2 carrier. Am J Transplant. 2006 Dec; 6(12):2861-70.
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On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase. J Mol Biol. 2002 Dec 06; 324(4):677-90.
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Intrahepatic biliary anatomy of living adult liver donors: correlation of mangafodipir trisodium-enhanced MR cholangiography and intraoperative cholangiography. AJR Am J Roentgenol. 2002 Nov; 179(5):1281-6.
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Purinergic and adrenergic agonists synergize in stimulating vasopressin and oxytocin release. J Neurosci. 2000 Dec 01; 20(23):8868-75.
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Efficacy and safety of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. Multicenter phase III clinical trials. Efficacy of early imaging. J Magn Reson Imaging. 2000 Nov; 12(5):689-701.
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Safety and efficacy of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. multicenter phase III clinical trials (safety). J Magn Reson Imaging. 2000 Jul; 12(1):186-97.