 Pyridoxal Phosphate
"Pyridoxal Phosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
| Descriptor ID |
D011732
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| MeSH Number(s) |
D03.383.725.676.925.500.500 D08.211.740
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| Concept/Terms |
Pyridoxal Phosphate- Pyridoxal Phosphate
- Phosphate, Pyridoxal
- Pyridoxal-P
- Pyridoxal P
- Pyridoxal 5-Phosphate
- Pyridoxal 5 Phosphate
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Below are MeSH descriptors whose meaning is more general than "Pyridoxal Phosphate".
Below are MeSH descriptors whose meaning is more specific than "Pyridoxal Phosphate".
This graph shows the total number of publications written about "Pyridoxal Phosphate" by people in this website by year, and whether "Pyridoxal Phosphate" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 2000 | 3 | 0 | 3 | | 2002 | 1 | 1 | 2 | | 2006 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pyridoxal Phosphate" by people in Profiles.
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Michalska K, Wellington S, Maltseva N, Jedrzejczak R, Selem-Mojica N, Rosas-Becerra LR, Barona-Gómez F, Hung DT, Joachimiak A. Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB. Protein Sci. 2021 09; 30(9):1904-1918.
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Veeravigrom M, Damrongphol P, Ittiwut R, Ittiwut C, Suphapeetiporn K, Shotelersuk V. Pyridoxal 5?-phosphate-responsive epilepsy with novel mutations in the PNPO gene: a case report. Genet Mol Res. 2015 Oct 30; 14(4):14130-5.
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Chi W, Zhang L, Du W, Zhuang X. A nutritional conditional lethal mutant due to pyridoxine 5'-phosphate oxidase deficiency in Drosophila melanogaster. G3 (Bethesda). 2014 Apr 16; 4(6):1147-54.
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Witus LS, Moore T, Thuronyi BW, Esser-Kahn AP, Scheck RA, Iavarone AT, Francis MB. Identification of highly reactive sequences for PLP-mediated bioconjugation using a combinatorial peptide library. J Am Chem Soc. 2010 Dec 01; 132(47):16812-7.
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Avila JG, Wang Y, Barbaro B, Gangemi A, Qi M, Kuechle J, Doubleday N, Doubleday M, Churchill T, Salehi P, Shapiro J, Philipson LH, Benedetti E, Lakey JR, Oberholzer J. Improved outcomes in islet isolation and transplantation by the use of a novel hemoglobin-based O2 carrier. Am J Transplant. 2006 Dec; 6(12):2861-70.
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Kulik V, Weyand M, Seidel R, Niks D, Arac D, Dunn MF, Schlichting I. On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase. J Mol Biol. 2002 Dec 06; 324(4):677-90.
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Kapoor V, Peterson MS, Baron RL, Patel S, Eghtesad B, Fung JJ. Intrahepatic biliary anatomy of living adult liver donors: correlation of mangafodipir trisodium-enhanced MR cholangiography and intraoperative cholangiography. AJR Am J Roentgenol. 2002 Nov; 179(5):1281-6.
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Kapoor JR, Sladek CD. Purinergic and adrenergic agonists synergize in stimulating vasopressin and oxytocin release. J Neurosci. 2000 Dec 01; 20(23):8868-75.
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Federle M, Chezmar J, Rubin DL, Weinreb J, Freeny P, Schmiedl UP, Brown JJ, Borrello JA, Lee JK, Semelka RC, Mattrey R, Dachman AH, Saini S, Harms SE, Mitchell DG, Anderson MW, Halford HH, Bennett WF, Young SW, Rifkin M, Gay SB, Ballerini R, Sherwin PF, Robison RO. Efficacy and safety of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. Multicenter phase III clinical trials. Efficacy of early imaging. J Magn Reson Imaging. 2000 Nov; 12(5):689-701.
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Federle MP, Chezmar JL, Rubin DL, Weinreb JC, Freeny PC, Semelka RC, Brown JJ, Borello JA, Lee JK, Mattrey R, Dachman AH, Saini S, Harmon B, Fenstermacher M, Pelsang RE, Harms SE, Mitchell DG, Halford HH, Anderson MW, Johnson CD, Francis IR, Bova JG, Kenney PJ, Klippenstein DL, Foster GS, Turner DA. Safety and efficacy of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: results of the U.S. multicenter phase III clinical trials (safety). J Magn Reson Imaging. 2000 Jul; 12(1):186-97.
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