"Vitamin B 6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
VITAMIN B 6 refers to several PICOLINES (especially PYRIDOXINE; PYRIDOXAL; & PYRIDOXAMINE) that are efficiently converted by the body to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into PYRIDOXAMINE phosphate. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). Most of vitamin B6 is eventually degraded to PYRIDOXIC ACID and excreted in the urine.
Descriptor ID |
D025101
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MeSH Number(s) |
D03.383.725.676.925
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Vitamin B 6".
Below are MeSH descriptors whose meaning is more specific than "Vitamin B 6".
This graph shows the total number of publications written about "Vitamin B 6" by people in this website by year, and whether "Vitamin B 6" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2012 | 1 | 0 | 1 |
2014 | 0 | 1 | 1 |
2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Vitamin B 6" by people in Profiles.
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Drosophila carrying epilepsy-associated variants in the vitamin B6 metabolism gene PNPO display allele- and diet-dependent phenotypes. Proc Natl Acad Sci U S A. 2022 03 01; 119(9).
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A nutritional conditional lethal mutant due to pyridoxine 5'-phosphate oxidase deficiency in Drosophila melanogaster. G3 (Bethesda). 2014 Apr 16; 4(6):1147-54.
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Prediagnostic plasma pyridoxal 5'-phosphate (vitamin b6) levels and invasive breast carcinoma risk: the multiethnic cohort. Cancer Epidemiol Biomarkers Prev. 2012 Nov; 21(11):1942-8.