 Penicillamine
"Penicillamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
| Descriptor ID |
D010396
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| MeSH Number(s) |
D02.886.030.786 D12.125.166.786
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| Concept/Terms |
Penicillamine- Penicillamine
- D-Penicillamine
- D Penicillamine
- beta,beta-Dimethylcysteine
- beta,beta Dimethylcysteine
- Mercaptovaline
- D-3-Mercaptovaline
- D 3 Mercaptovaline
- Dimethylcysteine
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Below are MeSH descriptors whose meaning is more general than "Penicillamine".
Below are MeSH descriptors whose meaning is more specific than "Penicillamine".
This graph shows the total number of publications written about "Penicillamine" by people in this website by year, and whether "Penicillamine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1986 | 0 | 1 | 1 | | 1997 | 0 | 2 | 2 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Penicillamine" by people in Profiles.
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Malieckal DA, Modersitzki F, Mara K, Enders FT, Asplin JR, Goldfarb DS. Effect of increasing doses of cystine-binding thiol drugs on cystine capacity in patients with cystinuria. Urolithiasis. 2019 Dec; 47(6):549-555.
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Capone K, Azzam RK. Wilson's Disease: A Review for the General Pediatrician. Pediatr Ann. 2018 Nov 01; 47(11):e440-e444.
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Bennett JA, Clarke JT, Ioffreda MD. Annular keratotic papules on the extremities. J Am Acad Dermatol. 2015 Nov; 73(5):891-3.
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Dolin DJ, Asplin JR, Flagel L, Grasso M, Goldfarb DS. Effect of cystine-binding thiol drugs on urinary cystine capacity in patients with cystinuria. J Endourol. 2005 Apr; 19(3):429-32.
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Coe FL, Clark C, Parks JH, Asplin JR. Solid phase assay of urine cystine supersaturation in the presence of cystine binding drugs. J Urol. 2001 Aug; 166(2):688-93.
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Chen JW, Eatock RA. Major potassium conductance in type I hair cells from rat semicircular canals: characterization and modulation by nitric oxide. J Neurophysiol. 2000 Jul; 84(1):139-51.
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Nakagawa Y, Coe FL. A modified cyanide-nitroprusside method for quantifying urinary cystine concentration that corrects for creatinine interference. Clin Chim Acta. 1999 Nov; 289(1-2):57-68.
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Brorson JR, Zhang H. Disrupted [Ca2+]i homeostasis contributes to the toxicity of nitric oxide in cultured hippocampal neurons. J Neurochem. 1997 Nov; 69(5):1882-9.
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Karrison TG. Use of Irwin's restricted mean as an index for comparing survival in different treatment groups--interpretation and power considerations. Control Clin Trials. 1997 Apr; 18(2):151-67.
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Key LL, Hoch S, Cairns L, Carnes D, Beyer E, Anast CS. Monocyte bone degradation: in vitro analysis of monocyte activity in patients with juvenile rheumatoid arthritis. J Pediatr. 1986 Mar; 108(3):405-9.
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