"Thiorphan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.
| Descriptor ID |
D015244
|
| MeSH Number(s) |
D02.886.030.893 D12.125.166.893 D12.125.481.700.750
|
| Concept/Terms |
Thiorphan- Thiorphan
- Tiorphan
- (3-Mercapto-2-benzylpropionyl)glycine
|
Below are MeSH descriptors whose meaning is more general than "Thiorphan".
Below are MeSH descriptors whose meaning is more specific than "Thiorphan".
This graph shows the total number of publications written about "Thiorphan" by people in this website by year, and whether "Thiorphan" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2002 | 2 | 0 | 2 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thiorphan" by people in Profiles.
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Granulocyte-colony stimulating factor attenuates oligomeric amyloid ß neurotoxicity by activation of neprilysin. PLoS One. 2014; 9(7):e103458.
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Effects of chronic neutral endopeptidase inhibition on the progression of left ventricular dysfunction and remodeling in dogs with moderate heart failure. Cardiovasc Drugs Ther. 2002 May; 16(3):209-14.
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The treatment of acute diarrhea in the third millennium: a pediatrician's perspective. Acta Gastroenterol Belg. 2002 Jan-Mar; 65(1):33-6.
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Angiotensin-converting enzyme and neutral endopeptidase modulate smokeless tobacco-induced increase in macromolecular efflux from the oral mucosa in vivo. J Lab Clin Med. 1997 Oct; 130(4):395-400.
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Neutral endopeptidase modulates VIP-induced vasodilation in hamster cheek pouch vessels in situ. Am J Physiol. 1996 Aug; 271(2 Pt 2):R393-7.