"Nitrosourea Compounds" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of compounds in which the core molecule is R-NO, where R is UREA.
| Descriptor ID |
D009607
|
| MeSH Number(s) |
D02.654.692 D02.948.594
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Nitrosourea Compounds".
Below are MeSH descriptors whose meaning is more specific than "Nitrosourea Compounds".
This graph shows the total number of publications written about "Nitrosourea Compounds" by people in this website by year, and whether "Nitrosourea Compounds" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nitrosourea Compounds" by people in Profiles.
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Phase II trial of carmustine plus O(6)-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma. J Clin Oncol. 2002 May 01; 20(9):2277-83.
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Drug delivery to tumors of the central nervous system. Curr Neurol Neurosci Rep. 2001 May; 1(3):210-6.
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In vitro carcinogenesis of hamster pancreatic duct cells: cellular and molecular alterations. Carcinogenesis. 1994 Sep; 15(9):1979-84.
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Acute leukemia occurring after radiotherapy and chemotherapy with a nitrosourea, PCNU. Invest New Drugs. 1988 Jun; 6(2):121-4.
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An analysis of 1-(2-chloroethyl)-1-nitrosourea activity at the cellular level. J Med Chem. 1983 Nov; 26(11):1656-9.
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Renal and metabolic toxicities of cancer chemotherapy. Semin Oncol. 1982 Mar; 9(1):75-83.
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A randomized comparison of two dosage schedules of methyl CCNU: three-week versus six-week treatments. Cancer. 1979 Sep; 44(3):824-30.
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Hexamethylmelamine, bleomycin, and CCNU chemotherapy for patients with squamous cell carcinoma, large cell carcinoma, and adenocarcinoma of the lung unresponsive to cyclophosphamide, adriamycin, methotrexate, and procarbazine. Cancer Treat Rep. 1978 Apr; 62(4):567-9.
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The effect of autologous serum on lymphocyte response to human leukemia cells. Blood. 1974 Jun; 43(6):781-7.
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A comparison of the effects of alkylating agents 1,3-bis(2-chloroethyl)-1-nitrosourea, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea and nitrogen mustard on nuclear RNA synthesis and processing. Biochim Biophys Acta. 1974 May 31; 349(3):389-401.