"Methylnitrosourea" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nitrosourea compound with alkylating, carcinogenic, and mutagenic properties.
| Descriptor ID |
D008770
|
| MeSH Number(s) |
D02.654.692.480 D02.948.594.490
|
| Concept/Terms |
Methylnitrosourea- Methylnitrosourea
- Nitrosomethylurea
- N-Methyl-N-nitrosourea
- N Methyl N nitrosourea
|
Below are MeSH descriptors whose meaning is more general than "Methylnitrosourea".
Below are MeSH descriptors whose meaning is more specific than "Methylnitrosourea".
This graph shows the total number of publications written about "Methylnitrosourea" by people in this website by year, and whether "Methylnitrosourea" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Methylnitrosourea" by people in Profiles.
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Individual differences in pre-carcinogen cytokine and corticosterone concentrations and depressive-like behavior predict tumor onset in rats exposed to a carcinogen. Psychoneuroendocrinology. 2013 Jun; 38(6):800-7.
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In vitro carcinogenesis of hamster pancreatic duct cells: cellular and molecular alterations. Carcinogenesis. 1994 Sep; 15(9):1979-84.
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Genomic p53 mutation in a chemically induced hamster pancreatic ductal adenocarcinoma. Cancer Res. 1994 Jul 15; 54(14):3878-83.
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Experimental intravesical therapy for superficial transitional cell carcinoma in a rat bladder tumor model. J Urol. 1991 Mar; 145(3):647-53.
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Characterization of an N-methyl-N-nitrosourea-induced autochthonous rat bladder cancer model. Cancer Res. 1990 Oct 15; 50(20):6668-74.
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Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents. Carcinogenesis. 1989 Sep; 10(9):1613-9.
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Intracellular activation of cytotoxic agents: kinetic models for methylnitrosoureas and N-methyl-N'-nitro-N-nitrosoguanidine in cell culture. Chem Res Toxicol. 1989 May-Jun; 2(3):157-61.
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Sequence specificity of guanine alkylation and repair. Carcinogenesis. 1988 Nov; 9(11):2139-43.
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Extent of formation of O4-methylthymidine in calf thymus DNA methylated by N-methyl-N-nitrosourea and lack of repair of this product by rat liver O6-alkylguanine-DNA-alkyltransferase. Carcinogenesis. 1985 Nov; 6(11):1611-4.