"Lipopolysaccharides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
| Descriptor ID |
D008070
|
| MeSH Number(s) |
D09.400.500 D09.698.718.450 D10.494 D23.050.161.616.525 D23.946.123.329.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lipopolysaccharides".
Below are MeSH descriptors whose meaning is more specific than "Lipopolysaccharides".
This graph shows the total number of publications written about "Lipopolysaccharides" by people in this website by year, and whether "Lipopolysaccharides" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 2 | 3 |
| 1994 | 0 | 2 | 2 |
| 1995 | 3 | 1 | 4 |
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 5 | 5 |
| 1999 | 2 | 6 | 8 |
| 2000 | 0 | 5 | 5 |
| 2001 | 1 | 7 | 8 |
| 2002 | 2 | 7 | 9 |
| 2003 | 3 | 5 | 8 |
| 2004 | 3 | 4 | 7 |
| 2005 | 3 | 3 | 6 |
| 2006 | 0 | 6 | 6 |
| 2007 | 3 | 10 | 13 |
| 2008 | 2 | 3 | 5 |
| 2009 | 3 | 7 | 10 |
| 2010 | 4 | 3 | 7 |
| 2011 | 1 | 5 | 6 |
| 2012 | 3 | 7 | 10 |
| 2013 | 4 | 9 | 13 |
| 2014 | 4 | 8 | 12 |
| 2015 | 5 | 10 | 15 |
| 2016 | 2 | 7 | 9 |
| 2017 | 5 | 3 | 8 |
| 2018 | 5 | 3 | 8 |
| 2019 | 0 | 3 | 3 |
| 2020 | 1 | 5 | 6 |
| 2021 | 0 | 4 | 4 |
| 2022 | 1 | 3 | 4 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Lipopolysaccharides" by people in Profiles.
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Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE. Nature. 2023 Feb; 614(7948):530-538.
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Limosilactobacillus reuteri normalizes blood-brain barrier dysfunction and neurodevelopment deficits associated with prenatal exposure to lipopolysaccharide. Gut Microbes. 2023 Jan-Dec; 15(1):2178800.
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Different Hypothalamic Mechanisms Control Decreased Circulating Thyroid Hormone Levels in Infection and Fasting-Induced Non-Thyroidal Illness Syndrome in Male Thyroid Hormone Action Indicator Mice. Thyroid. 2023 01; 33(1):109-118.
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TLR4 activation induces inflammatory vascular permeability via Dock1 targeting and NOX4 upregulation. Biochim Biophys Acta Mol Basis Dis. 2022 12 01; 1868(12):166562.
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BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia. Mol Neurodegener. 2022 05 07; 17(1):33.
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Structural basis of lipopolysaccharide maturation by the O-antigen ligase. Nature. 2022 04; 604(7905):371-376.
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Essential role for paxillin tyrosine phosphorylation in LPS-induced mitochondrial fission, ROS generation and lung endothelial barrier loss. Sci Rep. 2021 09 02; 11(1):17546.
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Racial differences across pregnancy in maternal pro-inflammatory immune responsivity and its regulation by glucocorticoids. Psychoneuroendocrinology. 2021 09; 131:105333.
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Sex-specific differences in peripheral blood leukocyte transcriptional response to LPS are enriched for HLA region and X chromosome genes. Sci Rep. 2021 01 13; 11(1):1107.
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Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin. Nat Immunol. 2021 02; 22(2):154-165.