 Lipopolysaccharides
"Lipopolysaccharides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
| Descriptor ID |
D008070
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| MeSH Number(s) |
D09.400.500 D09.698.718.450 D10.494 D23.050.161.616.525 D23.946.123.329.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lipopolysaccharides".
Below are MeSH descriptors whose meaning is more specific than "Lipopolysaccharides".
This graph shows the total number of publications written about "Lipopolysaccharides" by people in this website by year, and whether "Lipopolysaccharides" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 1 | 1 | 2 | | 1990 | 0 | 1 | 1 | | 1991 | 4 | 3 | 7 | | 1992 | 1 | 0 | 1 | | 1993 | 1 | 2 | 3 | | 1994 | 0 | 3 | 3 | | 1995 | 3 | 1 | 4 | | 1996 | 0 | 2 | 2 | | 1997 | 0 | 2 | 2 | | 1998 | 0 | 6 | 6 | | 1999 | 2 | 6 | 8 | | 2000 | 0 | 5 | 5 | | 2001 | 1 | 7 | 8 | | 2002 | 2 | 8 | 10 | | 2003 | 3 | 5 | 8 | | 2004 | 3 | 5 | 8 | | 2005 | 3 | 4 | 7 | | 2006 | 0 | 6 | 6 | | 2007 | 4 | 11 | 15 | | 2008 | 2 | 3 | 5 | | 2009 | 3 | 7 | 10 | | 2010 | 4 | 3 | 7 | | 2011 | 1 | 5 | 6 | | 2012 | 3 | 7 | 10 | | 2013 | 4 | 9 | 13 | | 2014 | 4 | 8 | 12 | | 2015 | 5 | 10 | 15 | | 2016 | 2 | 6 | 8 | | 2017 | 5 | 3 | 8 | | 2018 | 5 | 3 | 8 | | 2019 | 0 | 3 | 3 | | 2020 | 1 | 4 | 5 | | 2021 | 0 | 4 | 4 | | 2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "Lipopolysaccharides" by people in Profiles.
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Sudwarts A, Ramesha S, Gao T, Ponnusamy M, Wang S, Hansen M, Kozlova A, Bitarafan S, Kumar P, Beaulieu-Abdelahad D, Zhang X, Collier L, Szekeres C, Wood LB, Duan J, Thinakaran G, Rangaraju S. BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia. Mol Neurodegener. 2022 05 07; 17(1):33.
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Ashraf KU, Nygaard R, Vickery ON, Erramilli SK, Herrera CM, McConville TH, Petrou VI, Giacometti SI, Dufrisne MB, Nosol K, Zinkle AP, Graham CLB, Loukeris M, Kloss B, Skorupinska-Tudek K, Swiezewska E, Roper DI, Clarke OB, Uhlemann AC, Kossiakoff AA, Trent MS, Stansfeld PJ, Mancia F. Structural basis of lipopolysaccharide maturation by the O-antigen ligase. Nature. 2022 04; 604(7905):371-376.
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Fu P, Epshtein Y, Ramchandran R, Mascarenhas JB, Cress AE, Jacobson J, Garcia JGN, Natarajan V. Essential role for paxillin tyrosine phosphorylation in LPS-induced mitochondrial fission, ROS generation and lung endothelial barrier loss. Sci Rep. 2021 09 02; 11(1):17546.
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Gyllenhammer LE, Entringer S, Buss C, Simhan HN, Grobman WA, Borders AE, Wadhwa PD. Racial differences across pregnancy in maternal pro-inflammatory immune responsivity and its regulation by glucocorticoids. Psychoneuroendocrinology. 2021 09; 131:105333.
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Stein MM, Conery M, Magnaye KM, Clay SM, Billstrand C, Nicolae R, Naughton K, Ober C, Thompson EE. Sex-specific differences in peripheral blood leukocyte transcriptional response to LPS are enriched for HLA region and X chromosome genes. Sci Rep. 2021 01 13; 11(1):1107.
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Russo AJ, Vasudevan SO, Méndez-Huergo SP, Kumari P, Menoret A, Duduskar S, Wang C, Pérez Sáez JM, Fettis MM, Li C, Liu R, Wanchoo A, Chandiran K, Ruan J, Vanaja SK, Bauer M, Sponholz C, Hudalla GA, Vella AT, Zhou B, Deshmukh SD, Rabinovich GA, Rathinam VA. Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin. Nat Immunol. 2021 02; 22(2):154-165.
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Gyllenhammer LE, Entringer S, Buss C, Simhan HN, Grobman WA, Adam EK, Keenan-Devlin L, Borders AE, Wadhwa PD. Prospective association of maternal immune pro-inflammatory responsivity and regulation in pregnancy with length of gestation. Am J Reprod Immunol. 2021 05; 85(5):e13366.
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Ha CWY, Martin A, Sepich-Poore GD, Shi B, Wang Y, Gouin K, Humphrey G, Sanders K, Ratnayake Y, Chan KSL, Hendrick G, Caldera JR, Arias C, Moskowitz JE, Ho Sui SJ, Yang S, Underhill D, Brady MJ, Knott S, Kaihara K, Steinbaugh MJ, Li H, McGovern DPB, Knight R, Fleshner P, Devkota S. Translocation of Viable Gut Microbiota to Mesenteric Adipose Drives Formation of Creeping Fat in Humans. Cell. 2020 10 29; 183(3):666-683.e17.
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Detter MR, Shenkar R, Benavides CR, Neilson CA, Moore T, Lightle R, Hobson N, Shen L, Cao Y, Girard R, Zhang D, Griffin E, Gallione CJ, Awad IA, Marchuk DA. Novel Murine Models of Cerebral Cavernous Malformations. Angiogenesis. 2020 11; 23(4):651-666.
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Choi JW, Withers SS, Chang H, Spanier JA, De La Trinidad VL, Panesar H, Fife BT, Sciammas R, Sparger EE, Moore PF, Kent MS, Rebhun RB, McSorley SJ. Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function. PLoS One. 2020; 15(7):e0235518.
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