Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.

Stefka AT, Johnson D, Rosebeck S, Park JH, Nakamura Y, Jakubowiak AJ. Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models. Cancer Med. 2020 01; 9(1):324-334.

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subject areas

Animals
Antineoplastic Combined Chemotherapy Protocols
Apoptosis
Cell Cycle Checkpoints
Cell Line, Tumor
Drug Synergism
Female
Humans
Leukocytes, Mononuclear
Mice
Mitogen-Activated Protein Kinase Kinases
Multiple Myeloma
Primary Cell Culture
Protein Kinase Inhibitors
Quinolones
Thiophenes
Xenograft Model Antitumor Assays

authors with profiles

Andrzej Jakubowiak
Yusuke Nakamura