"DNA Ligases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Poly(deoxyribonucleotide):poly(deoxyribonucleotide)ligases. Enzymes that catalyze the joining of preformed deoxyribonucleotides in phosphodiester linkage during genetic processes during repair of a single-stranded break in duplex DNA. The class includes both EC 6.5.1.1 (ATP) and EC 6.5.1.2 (NAD).
| Descriptor ID |
D011088
|
| MeSH Number(s) |
D08.811.074.500 D08.811.464.754.600
|
| Concept/Terms |
DNA Ligases- DNA Ligases
- Ligases, DNA
- Polydeoxyribonucleotide Ligases
- Ligases, Polydeoxyribonucleotide
- Polydeoxyribonucleotide Synthetases
- Synthetases, Polydeoxyribonucleotide
- DNA Joinases
- Joinases, DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA Ligases".
Below are MeSH descriptors whose meaning is more specific than "DNA Ligases".
This graph shows the total number of publications written about "DNA Ligases" by people in this website by year, and whether "DNA Ligases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 1 | 2 |
| 2001 | 2 | 0 | 2 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Ligases" by people in Profiles.
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Role for Artemis nuclease in the repair of radiation-induced DNA double strand breaks by alternative end joining. DNA Repair (Amst). 2015 Jul; 31:29-40.
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Analysis of the role of homology arms in gene-targeting vectors in human cells. PLoS One. 2014; 9(9):e108236.
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C-Terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin. Biochem Biophys Res Commun. 2013 Sep 20; 439(2):173-8.
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DNA ligase IV and artemis act cooperatively to suppress homologous recombination in human cells: implications for DNA double-strand break repair. PLoS One. 2013; 8(8):e72253.
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Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs. J Exp Med. 2012 May 07; 209(5):955-63.
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[Mechanisms of chromosomal DNA strand break repair in human cells]. Tanpakushitsu Kakusan Koso. 2009 Mar; 54(4 Suppl):472-8.
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Impact of non-homologous end-joining deficiency on random and targeted DNA integration: implications for gene targeting. Nucleic Acids Res. 2008 Nov; 36(19):6333-42.
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Loss of DNA ligase IV prevents recognition of DNA by double-strand break repair proteins XRCC4 and XLF. Nucleic Acids Res. 2008 Oct; 36(18):5773-86.
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Identification of recognition residues for ligation-based detection and quantitation of pseudouridine and N6-methyladenosine. Nucleic Acids Res. 2007; 35(18):6322-9.
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Simple one-week method to construct gene-targeting vectors: application to production of human knockout cell lines. Biotechniques. 2006 Sep; 41(3):311-6.