Andrew Dahl
Title | Assistant Professor |
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Institution | University of Chicago |
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Department | Medicine-Genetic Medicine |
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Address | Chicago IL 60637
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Email |  |
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vCard | Download vCard |
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Overview Our group focuses on computational approaches to discover and characterize context-specific genetic effects on complex disorders. This includes polygenic methods for gene-environment interaction, gene-gene interaction, and genetic subtypes of disease. We are particularly interested in applications to asthma, major depressive disorder, single cell omics, and cross-population portability of genetic predictions. Our long-term goal is to advance equitable precision treatment by embracing the full diversity of human contexts.
Biography Oxford | PhD | 10/2016 | Gen Med and Stats | UChicago | MS | 06/2012 | Stats | UChicago | Hon BS | 06/2012 | Math | UChicago | BA | 06/2012 | Econ |
2012 - 2016 | Clarendon Scholarship, Oxford | 2012 | Phi Beta Kappa, UChicago |
ORNG Applications Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Border R, Athanasiadis G, Buil A, Schork AJ, Cai N, Young AI, Werge T, Flint J, Kendler KS, Sankararaman S, Dahl AW, Zaitlen NA. Cross-trait assortative mating is widespread and inflates genetic correlation estimates. Science. 2022 11 18; 378(6621):754-761. PMID: 36395242.
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Sheppard B, Rappoport N, Loh PR, Sanders SJ, Zaitlen N, Dahl A. A model and test for coordinated polygenic epistasis in complex traits. Proc Natl Acad Sci U S A. 2021 04 13; 118(15). PMID: 33833052.
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Dahl A, Zaitlen N. Genetic Influences on Disease Subtypes. Annu Rev Genomics Hum Genet. 2020 08 31; 21:413-435. PMID: 32873077.
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Steinsaltz D, Dahl A, Wachter KW. On Negative Heritability and Negative Estimates of Heritability. Genetics. 2020 06; 215(2):343-357. PMID: 32291292.
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Dahl A, Nguyen K, Cai N, Gandal MJ, Flint J, Zaitlen N. A Robust Method Uncovers Significant Context-Specific Heritability in Diverse Complex Traits. Am J Hum Genet. 2020 01 02; 106(1):71-91. PMID: 31901249.
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Hernandez RD, Uricchio LH, Hartman K, Ye C, Dahl A, Zaitlen N. Ultrarare variants drive substantial cis heritability of human gene expression. Nat Genet. 2019 09; 51(9):1349-1355. PMID: 31477931.
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Dahl A, Cai N, Ko A, Laakso M, Pajukanta P, Flint J, Zaitlen N. Reverse GWAS: Using genetics to identify and model phenotypic subtypes. PLoS Genet. 2019 04; 15(4):e1008009. PMID: 30951530.
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Dahl A, Guillemot V, Mefford J, Aschard H, Zaitlen N. Adjusting for Principal Components of Molecular Phenotypes Induces Replicating False Positives. Genetics. 2019 04; 211(4):1179-1189. PMID: 30692194.
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Steinsaltz D, Dahl A, Wachter KW. Statistical properties of simple random-effects models for genetic heritability. Electron J Stat. 2018; 12(1):321-356. PMID: 30057658.
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Dahl A, Iotchkova V, Baud A, Johansson Å, Gyllensten U, Soranzo N, Mott R, Kranis A, Marchini J. A multiple-phenotype imputation method for genetic studies. Nat Genet. 2016 Apr; 48(4):466-72. PMID: 26901065.
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Year | Publications |
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2016 | 1 | 2018 | 1 | 2019 | 3 | 2020 | 3 | 2021 | 1 | 2022 | 1 |
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