"Quinine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
Descriptor ID |
D011803
|
MeSH Number(s) |
D03.132.206.719 D03.605.687.762 D03.633.100.810.762
|
Concept/Terms |
Quinine Sulfate- Quinine Sulfate
- Sulfate, Quinine
- Quinine Sulphate
- Sulphate, Quinine
|
Below are MeSH descriptors whose meaning is more general than "Quinine".
Below are MeSH descriptors whose meaning is more specific than "Quinine".
This graph shows the total number of publications written about "Quinine" by people in this website by year, and whether "Quinine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
2000 | 1 | 0 | 1 |
2001 | 1 | 0 | 1 |
2009 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Quinine" by people in Profiles.
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Gustation assessment using the NIH Toolbox. Neurology. 2013 Mar 12; 80(11 Suppl 3):S20-4.
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The number of taste buds is related to bitter taste sensitivity in layer and broiler chickens. Anim Sci J. 2010 Apr; 81(2):240-4.
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Analgesia accompanying food consumption requires ingestion of hedonic foods. J Neurosci. 2009 Oct 14; 29(41):13053-62.
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Corticotropin-releasing factor overexpression decreases ethanol drinking and increases sensitivity to the sedative effects of ethanol. Psychopharmacology (Berl). 2004 Nov; 176(3-4):386-97.
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Comparison of the osmolyte transport properties induced by trAE1 versus IClswell in Xenopus oocytes. J Membr Biol. 2002 Jan 01; 185(1):57-63.
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Volume-activated trimethylamine oxide efflux in red blood cells of spiny dogfish (Squalus acanthias). Am J Physiol Regul Integr Comp Physiol. 2001 Sep; 281(3):R803-10.
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Crystal and molecular structure of a new cobalt complex of quinine. Enantiomer. 2001; 6(4):201-10.
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Fulminant babesiosis treated with clindamycin, quinine, and whole-blood exchange transfusion. Transfusion. 2000 Mar; 40(3):375-80.
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Evolving clinical problems with Streptococcus pneumoniae: increasing resistance to antimicrobial agents, and failure of traditional optochin identification in Chicago, Illinois, between 1993 and 1996. Diagn Microbiol Infect Dis. 1997 Dec; 29(4):209-14.
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Further investigation of ionic diffusive properties and of NH4+ pathways in Xenopus laevis oocyte cell membrane. Pflugers Arch. 1996 Feb; 431(4):658-67.