High-Throughput Nucleotide Sequencing
"High-Throughput Nucleotide Sequencing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Techniques of nucleotide sequence analysis that increase the range, complexity, sensitivity, and accuracy of results by greatly increasing the scale of operations and thus the number of nucleotides, and the number of copies of each nucleotide sequenced. The sequencing may be done by analysis of the synthesis or ligation products, hybridization to preexisting sequences, etc.
| Descriptor ID |
D059014
|
| MeSH Number(s) |
E05.393.760.319
|
| Concept/Terms |
High-Throughput Nucleotide Sequencing- High-Throughput Nucleotide Sequencing
- High Throughput Nucleotide Sequencing
- Nucleotide Sequencing, High-Throughput
- Sequencing, High-Throughput Nucleotide
Massively-Parallel Sequencing- Massively-Parallel Sequencing
- Massively Parallel Sequencing
- Sequencing, Massively-Parallel
- Sequencings, Massively-Parallel
High-Throughput RNA Sequencing- High-Throughput RNA Sequencing
- High Throughput RNA Sequencing
- RNA Sequencing, High-Throughput
- Sequencing, High-Throughput RNA
Deep Sequencing- Deep Sequencing
- Deep Sequencings
- Sequencing, Deep
- Sequencings, Deep
High-Throughput DNA Sequencing- High-Throughput DNA Sequencing
- DNA Sequencing, High-Throughput
- High Throughput DNA Sequencing
- High-Throughput DNA Sequencings
- Sequencing, High-Throughput DNA
|
Below are MeSH descriptors whose meaning is more general than "High-Throughput Nucleotide Sequencing".
Below are MeSH descriptors whose meaning is more specific than "High-Throughput Nucleotide Sequencing".
This graph shows the total number of publications written about "High-Throughput Nucleotide Sequencing" by people in this website by year, and whether "High-Throughput Nucleotide Sequencing" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 3 | 4 |
| 2012 | 6 | 8 | 14 |
| 2013 | 0 | 10 | 10 |
| 2014 | 6 | 19 | 25 |
| 2015 | 10 | 26 | 36 |
| 2016 | 14 | 35 | 49 |
| 2017 | 9 | 27 | 36 |
| 2018 | 18 | 19 | 37 |
| 2019 | 13 | 28 | 41 |
| 2020 | 7 | 19 | 26 |
| 2021 | 10 | 14 | 24 |
| 2022 | 4 | 14 | 18 |
| 2023 | 2 | 15 | 17 |
| 2024 | 8 | 16 | 24 |
| 2025 | 3 | 9 | 12 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "High-Throughput Nucleotide Sequencing" by people in Profiles.
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Monogenic Type 1 Diabetes: A High Yield Pool in Which to Discover New Mechanisms and Candidate Therapeutics for Type 1 Diabetes. Cold Spring Harb Perspect Med. 2026 Feb 02; 16(2).
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Somatic Mutation Profiles of Colorectal Cancer by Birth Cohort. JCO Precis Oncol. 2025 Oct; 9:e2500717.
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Mutational signature analysis of chronic lymphocytic leukemia uncovering genomic patterns and prognostic implications. Am J Clin Pathol. 2025 Oct 04; 164(4):530-544.
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Improving the diagnosis of leptomeningeal metastases by molecular profiling of cell-free DNA from cerebrospinal fluid. Eur J Cancer. 2025 Oct 16; 229:115783.
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Detecting likely germline variants during tumor-based molecular profiling. J Clin Invest. 2025 Aug 01; 135(15).
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Analytical and clinical performance validation of HPV-SEQ, a novel NGS-based liquid biopsy platform for detection and quantification of human papilloma virus circulating tumor DNA. Oral Oncol. 2025 Aug; 167:107445.
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Automated and Decentralized Genomic Profiling of Plasma Cell-Free DNA for Identification of Targetable and Resistance Alterations in Advanced Solid Tumors. Clin Chem. 2025 Jun 03; 71(6):700-712.
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Comparative Molecular Profiling of "Mixed Endometrioid Adenocarcinoma and Adenosarcoma" of the Uterus and Ovary: A Multi-institutional Series of 14 Cases. Am J Surg Pathol. 2025 Apr 07; 49(8):789-799.
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Tutorial: guidelines for quality filtering of whole-exome and whole-genome sequencing data for population-scale association analyses. Nat Protoc. 2025 Sep; 20(9):2372-2382.
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Clinical use of measurable residual disease in adult ALL: recommendations from a panel of US experts. Blood Adv. 2025 Mar 25; 9(6):1442-1451.