Gentamicins
"Gentamicins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A complex of three different closely related aminoglycoside sulfates, Gentamicins C1, C2, and C1(subA), obtained from Micromonospora purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit protein synthesis (GENETIC TRANSLATION).
Descriptor ID |
D005839
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MeSH Number(s) |
D09.408.051.374
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Gentamicins".
Below are MeSH descriptors whose meaning is more specific than "Gentamicins".
This graph shows the total number of publications written about "Gentamicins" by people in this website by year, and whether "Gentamicins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1980 | 0 | 1 | 1 | 1982 | 1 | 1 | 2 | 1983 | 1 | 0 | 1 | 1985 | 0 | 2 | 2 | 1986 | 0 | 1 | 1 | 1987 | 1 | 1 | 2 | 1988 | 1 | 1 | 2 | 1990 | 1 | 0 | 1 | 1991 | 1 | 2 | 3 | 1994 | 1 | 0 | 1 | 1995 | 0 | 1 | 1 | 1997 | 1 | 0 | 1 | 1999 | 4 | 0 | 4 | 2001 | 1 | 2 | 3 | 2005 | 0 | 1 | 1 | 2006 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2010 | 1 | 0 | 1 | 2014 | 0 | 2 | 2 | 2017 | 0 | 1 | 1 | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Gentamicins" by people in Profiles.
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Kwong A, Cogan J, Hou Y, Antaya R, Hao M, Kim G, Lincoln V, Chen Q, Woodley DT, Chen M. Gentamicin Induces Laminin 332 and Improves Wound Healing in Junctional Epidermolysis Bullosa Patients with Nonsense Mutations. Mol Ther. 2020 05 06; 28(5):1327-1338.
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Crespo M, Vilar E, Tsai SY, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJ, Witherspoon M, Gordillo M, Xiang JZ, Maxfield FR, Lipkin S, Evans T, Chen S. Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing. Nat Med. 2017 Jul; 23(7):878-884.
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Ginn AN, Wiklendt AM, Zong Z, Lin RT, Teo JW, Tambyah PA, Peterson LR, Kaul K, Partridge SR, Iredell JR. Prediction of major antibiotic resistance in Escherichia coli and Klebsiella pneumoniae in Singapore, USA and China using a limited set of gene targets. Int J Antimicrob Agents. 2014 Jun; 43(6):563-5.
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Jain-Gupta N, Contreras-Rodriguez A, Smith GP, Garg VK, Witonsky SG, Isloor S, Vemulapalli R, Boyle SM, Sriranganathan N. Immunotherapeutics to prevent the replication of Brucella in a treatment failure mouse model. Vaccine. 2014 Feb 12; 32(8):918-23.
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Lyell DJ, Pullen K, Fuh K, Zamah AM, Caughey AB, Benitz W, El-Sayed YY. Daily compared with 8-hour gentamicin for the treatment of intrapartum chorioamnionitis: a randomized controlled trial. Obstet Gynecol. 2010 Feb; 115(2 Pt 1):344-349.
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Koyner JL, Sher Ali R, Murray PT. Antioxidants. Do they have a place in the prevention or therapy of acute kidney injury? Nephron Exp Nephrol. 2008; 109(4):e109-17.
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Zaborina O, Kohler JE, Wang Y, Bethel C, Shevchenko O, Wu L, Turner JR, Alverdy JC. Identification of multi-drug resistant Pseudomonas aeruginosa clinical isolates that are highly disruptive to the intestinal epithelial barrier. Ann Clin Microbiol Antimicrob. 2006 Jun 08; 5:14.
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Walanj R, Young P, Baker HM, Baker EN, Metcalf P, Chow JW, Lerner S, Vakulenko S, Smith CA. Purification, crystallization and preliminary X-ray analysis of Enterococcus faecium aminoglycoside-2''-phosphotransferase-Ib [APH(2'')-Ib]. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Apr 01; 61(Pt 4):410-3.
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Hilbi H, Segal G, Shuman HA. Icm/dot-dependent upregulation of phagocytosis by Legionella pneumophila. Mol Microbiol. 2001 Nov; 42(3):603-17.
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Jiang W, Zhou L, Breyer B, Feng T, Cheng H, Haydon R, Ishikawa A, He TC. Tetracycline-regulated gene expression mediated by a novel chimeric repressor that recruits histone deacetylases in mammalian cells. J Biol Chem. 2001 Nov 30; 276(48):45168-74.
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