"Puromycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.
| Descriptor ID |
D011691
|
| MeSH Number(s) |
D02.241.223.200.380 D03.633.100.759.590.138.711 D09.408.051.788 D13.570.583.138.711
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Puromycin".
Below are MeSH descriptors whose meaning is more specific than "Puromycin".
This graph shows the total number of publications written about "Puromycin" by people in this website by year, and whether "Puromycin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Puromycin" by people in Profiles.
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Puromycin-based vectors promote a ROS-dependent recruitment of PML to nuclear inclusions enriched with HSP70 and Proteasomes. BMC Cell Biol. 2009 May 01; 10:32.
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Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro. Biochemistry. 2006 Dec 19; 45(50):15111-9.
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Identification and characterization of HsIV HsIU (ClpQ ClpY) proteins involved in overall proteolysis of misfolded proteins in Escherichia coli. EMBO J. 1996 Dec 16; 15(24):6899-909.
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ADP-ribosylated elongation factor 2 (ADP-ribosyl-EF-2) is unable to promote translocation within the ribosome. FEBS Lett. 1990 Feb 26; 261(2):350-2.
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Stimulation of chondroitin sulfate proteoglycan production by chondrocytes in monolayer. Connect Tissue Res. 1975; 3(2):115-22.
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Stimulation of synthesis of free chondroitin sulfate chains by beta-D-xylosides in cultured cells. Proc Natl Acad Sci U S A. 1974 Oct; 71(10):4047-51.
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Mitochondrial protein synthesis: RNA with the properties of Eukaryotic messenger RNA. Proc Natl Acad Sci U S A. 1973 Feb; 70(2):350-3.
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Influence of metabolic inhibitors on the capacity of spleen cells to form hemolytic plaques and rosettes. Proc Soc Exp Biol Med. 1969 Jul; 131(3):835-40.
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Uracil incorporation and photopigment synthesis in Rhodospirillum rubrum. Biochim Biophys Acta. 1969 Jun 17; 182(2):322-33.
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Proteins associated with ribosomes in T4-infected E. coli. Cold Spring Harb Symp Quant Biol. 1969; 34:91-4.