 Serotonin Antagonists
"Serotonin Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or SEROTONIN RECEPTOR AGONISTS.
| Descriptor ID |
D012702
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| MeSH Number(s) |
D27.505.519.625.850.850 D27.505.696.577.850.850
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| Concept/Terms |
Serotonin Antagonists- Serotonin Antagonists
- Antagonists, Serotonin
- 5-Hydroxytryptamine Antagonists
- 5 Hydroxytryptamine Antagonists
- Antagonists, 5-HT
- Antagonists, 5 HT
- 5-HT Antagonists
- 5 HT Antagonists
- Antagonists, 5-Hydroxytryptamine
- Antagonists, 5 Hydroxytryptamine
- Antiserotonergic Agents
- Agents, Antiserotonergic
- Serotonin Blockaders
- Blockaders, Serotonin
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Below are MeSH descriptors whose meaning is more general than "Serotonin Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Serotonin Antagonists".
This graph shows the total number of publications written about "Serotonin Antagonists" by people in this website by year, and whether "Serotonin Antagonists" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 1 | 1 | | 1996 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 2 | 1 | 3 | | 1999 | 1 | 3 | 4 | | 2001 | 0 | 1 | 1 | | 2002 | 2 | 1 | 3 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 1 | 1 | 2 | | 2006 | 1 | 4 | 5 | | 2007 | 3 | 0 | 3 | | 2009 | 1 | 2 | 3 | | 2010 | 2 | 1 | 3 | | 2011 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Serotonin Antagonists" by people in Profiles.
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Basak S, Kumar A, Ramsey S, Gibbs E, Kapoor A, Filizola M, Chakrapani S. High-resolution structures of multiple 5-HT3AR-setron complexes reveal a novel mechanism of competitive inhibition. Elife. 2020 10 16; 9.
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Morton RA, Baptista-Hon DT, Hales TG, Lovinger DM. Agonist- and antagonist-induced up-regulation of surface 5-HT3 A receptors. Br J Pharmacol. 2015 Aug; 172(16):4066-77.
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Navari R. The current status of the use of palonosetron. Expert Opin Pharmacother. 2013 Jul; 14(10):1281-4.
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Kaushal N, Seminerio MJ, Robson MJ, McCurdy CR, Matsumoto RR. Pharmacological evaluation of SN79, a sigma (s) receptor ligand, against methamphetamine-induced neurotoxicity in vivo. Eur Neuropsychopharmacol. 2013 Aug; 23(8):960-71.
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Depuy SD, Kanbar R, Coates MB, Stornetta RL, Guyenet PG. Control of breathing by raphe obscurus serotonergic neurons in mice. J Neurosci. 2011 Feb 09; 31(6):1981-90.
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Kaushal J, Gupta MC, Kaushal V, Bhutani G, Dhankar R, Atri R, Verma S. Clinical evaluation of two antiemetic combinations palonosetron dexamethasone versus ondansetron dexamethasone in chemotherapy of head and neck cancer. Singapore Med J. 2010 Nov; 51(11):871-5.
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Avritscher EB, Shih YC, Sun CC, Gralla RJ, Grunberg SM, Xu Y, Elting LS. Cost-utility analysis of palonosetron-based therapy in preventing emesis among breast cancer patients. J Support Oncol. 2010 Nov-Dec; 8(6):242-51.
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Prasad B, Radulovacki M, Olopade C, Herdegen JJ, Logan T, Carley DW. Prospective trial of efficacy and safety of ondansetron and fluoxetine in patients with obstructive sleep apnea syndrome. Sleep. 2010 Jul; 33(7):982-9.
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Doi A, Ramirez JM. State-dependent interactions between excitatory neuromodulators in the neuronal control of breathing. J Neurosci. 2010 Jun 16; 30(24):8251-62.
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Navari RM. Palonosetron: a second generation 5-hydroxytryptamine 3 receptor antagonist. Expert Opin Drug Metab Toxicol. 2009 Dec; 5(12):1577-86.
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