"Ion Channel Gating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The opening and closing of ion channels due to a stimulus. The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. Gating is thought to involve conformational changes of the ion channel which alters selective permeability.
| Descriptor ID |
D015640
|
| MeSH Number(s) |
G02.111.820.400 G04.835.400 G07.265.625
|
| Concept/Terms |
Ion Channel Gating- Ion Channel Gating
- Gating, Ion Channel
- Gatings, Ion Channel
- Ion Channel Gatings
|
Below are MeSH descriptors whose meaning is more general than "Ion Channel Gating".
Below are MeSH descriptors whose meaning is more specific than "Ion Channel Gating".
This graph shows the total number of publications written about "Ion Channel Gating" by people in this website by year, and whether "Ion Channel Gating" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 8 | 11 |
| 1997 | 0 | 3 | 3 |
| 1998 | 7 | 3 | 10 |
| 1999 | 4 | 7 | 11 |
| 2000 | 3 | 2 | 5 |
| 2001 | 4 | 3 | 7 |
| 2002 | 6 | 7 | 13 |
| 2003 | 2 | 3 | 5 |
| 2004 | 9 | 5 | 14 |
| 2005 | 10 | 2 | 12 |
| 2006 | 10 | 11 | 21 |
| 2007 | 7 | 2 | 9 |
| 2008 | 6 | 5 | 11 |
| 2009 | 5 | 1 | 6 |
| 2010 | 8 | 5 | 13 |
| 2011 | 10 | 1 | 11 |
| 2012 | 8 | 1 | 9 |
| 2013 | 9 | 2 | 11 |
| 2014 | 3 | 1 | 4 |
| 2015 | 4 | 2 | 6 |
| 2016 | 0 | 3 | 3 |
| 2017 | 1 | 3 | 4 |
| 2018 | 8 | 2 | 10 |
| 2019 | 3 | 0 | 3 |
| 2020 | 3 | 0 | 3 |
| 2021 | 3 | 1 | 4 |
| 2022 | 2 | 0 | 2 |
| 2024 | 2 | 2 | 4 |
| 2025 | 3 | 5 | 8 |
| 2026 | 3 | 3 | 6 |
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Below are the most recent publications written about "Ion Channel Gating" by people in Profiles.
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Dynamical Nonequilibrium Molecular Dynamics Simulations Reveal Atomistic Steps of C-Type Inactivation in Cardiac hERG Channels. J Am Chem Soc. 2026 09 09; 148(35):37738-37750.
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Evolution of our understanding of the sodium channel fast inactivation: From Hodgkin and Huxley to the structural era. J Gen Physiol. 2026 Jul 06; 158(4).
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Human GlyRa2 pore dynamics in gating and inhibition. Structure. 2026 May 07; 34(5):798-813.e7.
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Conformational ensembles of the magnesium channel CorA reveal structural basis for channel gating. Proc Natl Acad Sci U S A. 2026 Feb 24; 123(8):e2512532123.
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Structural basis for domain coupling in heteromeric glycine receptors revealed by an atypical allosteric agonist. Sci Adv. 2026 Feb 13; 12(7):eaeb2036.
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The BK channel-NS1619 agonist complex reveals molecular insights into allosteric activation gating. Proc Natl Acad Sci U S A. 2026 Feb 03; 123(5):e2507707123.
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Conductance of a potassium channel in the limit of zero membrane potential. Biophys J. 2026 Aug 18; 125(16):4097-4102.
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Quantifying activation delay and the Cole-More shift via current derivatives. Biophys J. 2026 02 03; 125(3):688-696.
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Molecular basis of sodium channel inactivation. Nat Commun. 2025 Nov 26; 16(1):10565.
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Closed state structure of the pore revealed by uncoupled Shaker K+ channel. Nat Commun. 2025 Nov 19; 16(1):10180.