 Streptokinase
"Streptokinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Streptococcal fibrinolysin . An enzyme produced by hemolytic streptococci. It hydrolyzes amide linkages and serves as an activator of plasminogen. It is used in thrombolytic therapy and is used also in mixtures with streptodornase (STREPTODORNASE AND STREPTOKINASE). EC 3.4.-.
| Descriptor ID |
D013300
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| MeSH Number(s) |
D08.811.277.656.300.775 D12.776.124.125.662.537
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Streptokinase".
Below are MeSH descriptors whose meaning is more specific than "Streptokinase".
This graph shows the total number of publications written about "Streptokinase" by people in this website by year, and whether "Streptokinase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 1 | 0 | 1 | | 1986 | 2 | 0 | 2 | | 1988 | 0 | 1 | 1 | | 1989 | 0 | 1 | 1 | | 1995 | 2 | 0 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 2 | 0 | 2 | | 2002 | 1 | 0 | 1 |
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Below are the most recent publications written about "Streptokinase" by people in Profiles.
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Gladysheva IP, Sazonova IY, Chowdhry SA, Liu L, Turner RB, Reed GL. Chimerism reveals a role for the streptokinase Beta -domain in nonproteolytic active site formation, substrate, and inhibitor interactions. J Biol Chem. 2002 Jul 26; 277(30):26846-51.
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Gulati M, Furlong K, DeCara J, Spencer KT, Lang RM. Thrombolytic therapy of a left-sided prosthetic valve thrombosis without hemodynamic obstruction: a case report. J Am Soc Echocardiogr. 2001 Dec; 14(12):1230-4.
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Sazonova IY, Houng AK, Chowdhry SA, Robinson BR, Hedstrom L, Reed GL. The mechanism of a bacterial plasminogen activator intermediate between streptokinase and staphylokinase. J Biol Chem. 2001 Apr 20; 276(16):12609-13.
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Liu L, Sazonova IY, Turner RB, Chowdhry SA, Tsai J, Houng AK, Reed GL. Leucine 42 in the fibronectin motif of streptokinase plays a critical role in fibrin-independent plasminogen activation. J Biol Chem. 2000 Dec 01; 275(48):37686-91.
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Hill-West JL, Dunn RC, Hubbell JA. Local release of fibrinolytic agents for adhesion prevention. J Surg Res. 1995 Dec; 59(6):759-63.
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Lopez JA, Strickman NE, Jin BS, Li XG, Phan B, Zeluff BJ, Wilansky S. Successful thrombolysis for prosthetic pulmonary valve obstruction. Tex Heart Inst J. 1995; 22(2):197-9.
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Murthy MS, Summaria LJ, Miller RJ, Wyse TB, Goldschmidt RA, Scanlon EF. Inhibition of tumor implantation at sites of trauma by plasminogen activators. Cancer. 1991 Oct 15; 68(8):1724-30.
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Parent FN, Bernhard VM, Pabst TS, McIntyre KE, Hunter GC, Malone JM. Fibrinolytic treatment of residual thrombus after catheter embolectomy for severe lower limb ischemia. J Vasc Surg. 1989 Jan; 9(1):153-60.
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Novak RM, Leikin JB, Duarte B. Use of thrombolytic therapy in axillary-subclavian vein thrombosis. Am J Emerg Med. 1988 Mar; 6(2):120-3.
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Summaria L, Sandesara J, Yang G, Vagher JP, Caprini JA. In vitro comparison of fibrinolytic activity of plasminogen activators using a thrombelastographic method: in vivo evaluation of the B-chain-streptokinase complex in the dog model using pre-titered doses. Thromb Haemost. 1986 Aug 20; 56(1):71-9.
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