"Sulbactam" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone.
| Descriptor ID |
D013407
|
| MeSH Number(s) |
D02.065.589.099.750.812 D02.886.108.750.812 D03.633.100.300.750.812
|
| Concept/Terms |
Sulbactam- Sulbactam
- Penicillanic Acid Sulfone
- Sulfone, Penicillanic Acid
|
Below are MeSH descriptors whose meaning is more general than "Sulbactam".
Below are MeSH descriptors whose meaning is more specific than "Sulbactam".
This graph shows the total number of publications written about "Sulbactam" by people in this website by year, and whether "Sulbactam" was a major or minor topic of these publications.
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Below are the most recent publications written about "Sulbactam" by people in Profiles.
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Evolving clinical problems with Streptococcus pneumoniae: increasing resistance to antimicrobial agents, and failure of traditional optochin identification in Chicago, Illinois, between 1993 and 1996. Diagn Microbiol Infect Dis. 1997 Dec; 29(4):209-14.
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Molecular correlation between in vitro and in vivo activity of beta-lactam and beta-lactamase inhibitor combinations against methicillin-resistant Staphylococcus aureus. J Lab Clin Med. 1995 Feb; 125(2):200-11.
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Antibacterial activity of cefoperazone and cefoperazone plus sulbactam in a neutropenic site model. Diagn Microbiol Infect Dis. 1991 Mar-Apr; 14(2):147-55.
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A randomized, double-blind, placebo-controlled trial of oral antibiotic therapy following intravenous antibiotic therapy for postpartum endometritis. Obstet Gynecol. 1991 Jan; 77(1):60-2.
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Treatment evaluation of experimental staphylococcal infections: comparison of beta-lactam, lipopeptide, and glycopeptide antimicrobial therapy. J Lab Clin Med. 1990 Nov; 116(5):697-706.
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Comparative efficacy of cefoperazone, cefoperazone plus sulbactam, ciprofloxacin, clindamycin, metronidazole, and penicillin G against anaerobic bacteria in an animal model. J Lab Clin Med. 1990 Feb; 115(2):190-5.