"Lactams" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cyclic AMIDES formed from aminocarboxylic acids by the elimination of water. Lactims are the enol forms of lactams.
Descriptor ID |
D007769
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MeSH Number(s) |
D02.065.589 D03.383.411
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lactams".
Below are MeSH descriptors whose meaning is more specific than "Lactams".
This graph shows the total number of publications written about "Lactams" by people in this website by year, and whether "Lactams" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 |
1998 | 1 | 0 | 1 |
2003 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2017 | 0 | 1 | 1 |
2019 | 0 | 1 | 1 |
2020 | 0 | 1 | 1 |
2021 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lactams" by people in Profiles.
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Lorlatinib Exposed: A Far From Optimal Dose. Clin Pharmacol Ther. 2022 06; 111(6):1195-1196.
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Spectrum of Mechanisms of Resistance to Crizotinib and Lorlatinib in ROS1 Fusion-Positive Lung Cancer. Clin Cancer Res. 2021 05 15; 27(10):2899-2909.
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Investigating the impact of a ß-lactam allergy label on preoperative antibiotic prophylaxis administration. Infect Control Hosp Epidemiol. 2021 06; 42(6):710-714.
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Structural and biochemical analysis of the metallo-ß-lactamase L1 from emerging pathogen Stenotrophomonas maltophilia revealed the subtle but distinct di-metal scaffold for catalytic activity. Protein Sci. 2020 03; 29(3):723-743.
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The accelerated path of ceritinib: Translating pre-clinical development into clinical efficacy. Cancer Treat Rev. 2017 Apr; 55:181-189.
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Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer. Cancer Discov. 2016 10; 6(10):1118-1133.
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A system for the continuous directed evolution of proteases rapidly reveals drug-resistance mutations. Nat Commun. 2014 Oct 30; 5:5352.
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Abeta40-Lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid. Biochemistry. 2005 Apr 26; 44(16):6003-14.
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Modern management of acute otitis media. Pediatr Clin North Am. 2003 Apr; 50(2):399-411.
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Ertapenem once a day versus piperacillin-tazobactam every 6 hours for treatment of acute pelvic infections: a prospective, multicenter, randomized, double-blind study. Infect Dis Obstet Gynecol. 2003; 11(1):27-37.